$109 Cheap Flights from McAllen (MFE) to Indianapolis (IND)

View $109 flight on Mon, Dec 15, 2025Opens in a new window

Popular airlines from Miller Intl. Airport (MFE) to Indianapolis Intl. Airport (IND)

Cheap Flights from McAllen to Indianapolis (MFE-IND)

Prices were available within the past 7 days and start at $109 for one-way flights and $217 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Wed, Dec 3 - Wed, Dec 10
MFE
McAllen
IND
Indianapolis
$217 Roundtrip, found 4 hours ago
$217
Roundtrip
found 4 hours ago
Select Delta flight, departing Wed, Dec 3 from McAllen to Indianapolis, returning Wed, Dec 10, priced at $217 found 4 hours ago
Delta
Mon, Jan 12 - Tue, Jan 27
MFE
McAllen
IND
Indianapolis
$217 Roundtrip, found 1 hour ago
$217
Roundtrip
found 1 hour ago
Select Delta flight, departing Mon, Jan 12 from McAllen to Indianapolis, returning Tue, Jan 27, priced at $217 found 1 hour ago
Delta
Wed, Jan 7 - Sun, Jan 18
MFE
McAllen
IND
Indianapolis
$222 Roundtrip, found 4 days ago
$222
Roundtrip
found 4 days ago
Select Delta flight, departing Wed, Jan 7 from McAllen to Indianapolis, returning Sun, Jan 18, priced at $222 found 4 days ago
Delta
Sat, Jan 17 - Tue, Jan 27
MFE
McAllen
IND
Indianapolis
$222 Roundtrip, found 1 hour ago
$222
Roundtrip
found 1 hour ago
Select Delta flight, departing Sat, Jan 17 from McAllen to Indianapolis, returning Tue, Jan 27, priced at $222 found 1 hour ago
American Airlines
Sun, Jan 25 - Sat, Jan 31
MFE
McAllen
IND
Indianapolis
$225 Roundtrip, found 5 days ago
$225
Roundtrip
found 5 days ago
Select American Airlines flight, departing Sun, Jan 25 from McAllen to Indianapolis, returning Sat, Jan 31, priced at $225 found 5 days ago
Delta
Mon, Jan 26 - Sun, Feb 15
MFE
McAllen
IND
Indianapolis
$227 Roundtrip, found 1 hour ago
$227
Roundtrip
found 1 hour ago
Select Delta flight, departing Mon, Jan 26 from McAllen to Indianapolis, returning Sun, Feb 15, priced at $227 found 1 hour ago
Delta
Sat, Jan 10 - Sun, Jan 18
MFE
McAllen
IND
Indianapolis
$227 Roundtrip, found 4 days ago
$227
Roundtrip
found 4 days ago
Select Delta flight, departing Sat, Jan 10 from McAllen to Indianapolis, returning Sun, Jan 18, priced at $227 found 4 days ago
Delta
Sun, Jan 18 - Tue, Jan 27
MFE
McAllen
IND
Indianapolis
$232 Roundtrip, found 1 hour ago
$232
Roundtrip
found 1 hour ago
Select Delta flight, departing Sun, Jan 18 from McAllen to Indianapolis, returning Tue, Jan 27, priced at $232 found 1 hour ago
Delta
Mon, Jan 12 - Fri, Jan 30
MFE
McAllen
IND
Indianapolis
$238 Roundtrip, found 1 hour ago
$238
Roundtrip
found 1 hour ago
Select Delta flight, departing Mon, Jan 12 from McAllen to Indianapolis, returning Fri, Jan 30, priced at $238 found 1 hour ago
United
Wed, Dec 17 - Thu, Jan 1
MFE
McAllen
IND
Indianapolis
$239 Roundtrip, found 5 hours ago
$239
Roundtrip
found 5 hours ago
Select United flight, departing Wed, Dec 17 from McAllen to Indianapolis, returning Thu, Jan 1, priced at $239 found 5 hours ago

Find the cheapest month to fly from McAllen (MFE) to Indianapolis (IND)

September is typically the cheapest month to fly

From $190 - $448 per traveler.

Alternative airports near Indianapolis

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Indianapolis Intl. IND. Cheapest and Closest option available. Average driving time to city center is 19 minutes. Flights from $284
IND
Indianapolis Intl.
CheapestClosest
Average driving time to city center19 min
Flights from $284
Flights from McAllen (MFE) to Indianapolis (IND)
Origin airport
Miller Intl.
Destination airport
Indianapolis Intl.
Airlines serving
American Airlines, Delta, United
Roundtrip price
$216
Distance
1161 mi

McAllen to Indianapolis Flights

The cheapest times to fly from McAllen to Indianapolis

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from McAllen to Indianapolis are during the month of December. You can find some of the cheapest flights from McAllen to Indianapolis with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from McAllen to Indianapolis

Sunday is one of the best days to book for cheap flights from McAllen to Indianapolis: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from McAllen to Indianapolis

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from McAllen to Indianapolis in 2025. You can also book with separate airlines for your outbound and return journeys, from $109 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap McAllen to Indianapolis flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your McAllen to Indianapolis airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Miller Intl. Airport (MFE) to Indianapolis Intl. Airport (IND) cost?
Grab a cheap one-way flight from $109 or cheap return flight from $217 from Miller Intl. Airport (MFE) to Indianapolis Intl. Airport (IND) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Miller Intl. Airport (MFE) to Indianapolis Intl. Airport (IND)?
December is the most affordable month to fly from MFE to IND. Avoiding peak travel times is often the key to better flight prices.
What is the cheapest airline that flies from Miller Intl. Airport (MFE) to Indianapolis Intl. Airport (IND)?
To find the cheapest airline flying from MFE to IND, use Expedia's filter tool. Tailor your search based on your travel style, such as preferred carriers and flight duration. You can then sort your results by "Price (lowest to highest)" to see the most affordable options first.
How many flights per day from Miller Intl. Airport (MFE) to Indianapolis Intl. Airport (IND)?
You'll need to take a flight with a layover if you're traveling from Miller Intl. Airport (MFE) to Indianapolis Intl. Airport (IND). Direct flights don't operate daily on this route. However, just filter your search to include one or two stops to find the best option for your trip.
What day of the week has the most flights from MFE to IND?
Friday is generally the busiest day for flights, while Tuesday tends to be the quietest.* Remember that flight schedules can vary depending on a range of factors, such as the time of year and carrier.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Miller Intl. Airport (MFE) to Indianapolis Intl. Airport (IND)?
Book a flight from Miller Intl. Airport (MFE) to Indianapolis Intl. Airport (IND) that leaves before 3 PM to reduce the risk of cancellations and delays. Departures later than this are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Miller Intl. Airport (MFE) to Indianapolis Intl. Airport (IND) last-minute?
Holding off until right before your break to book your flight from MFE to IND generally means paying more. While you might find some last-minute discounts, there's no guarantee. Keep your travel schedule open for a better chance of scoring a bargain.
Is it cheaper to book a MFE to IND flight and hotel package?
Compared with arranging hotels and flights separately, booking a MFE to IND flight and hotel package with Expedia could lead to significant savings. Better still, having everything in one place takes the hassle out of planning your trip. Simply pick your flights and choose from our extensive range of hotels, then tailor your trip with other add-ons like tours and car rentals.
Can I cancel or change the date of my flight from Miller Intl. Airport (MFE) to Indianapolis Intl. Airport (IND)?
In most cases, you're able to cancel or reschedule your MFE to IND flight. However, additional fees may apply, especially if you made your booking more than 24 hours ago. Check your itinerary for the airline's guidelines and fees on flight changes, or if you want more details, head to our Customer Service portal.

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*Available to One Key members.