$181 Cheap Flights from Missoula (MSO) to Key West (EYW)

View $181 flight on Tue, Nov 18, 2025Opens in a new window

Popular airlines from Missoula Intl. Airport (MSO) to Key West Intl. Airport (EYW)

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Cheap Flights from Missoula to Key West (MSO-EYW)

Prices were available within the past 7 days and start at $181 for one-way flights and $359 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Sat, Nov 15 - Thu, Dec 4
MSO
Missoula
EYW
Key West
$359 Roundtrip, found 3 days ago
$359
Roundtrip
found 3 days ago
Select Delta flight, departing Sat, Nov 15 from Missoula to Key West, returning Thu, Dec 4, priced at $359 found 3 days ago
Delta
Tue, Nov 11 - Wed, Nov 19
MSO
Missoula
EYW
Key West
$374 Roundtrip, found 2 days ago
$374
Roundtrip
found 2 days ago
Select Delta flight, departing Tue, Nov 11 from Missoula to Key West, returning Wed, Nov 19, priced at $374 found 2 days ago
Delta
Sun, Nov 16 - Thu, Dec 4
MSO
Missoula
EYW
Key West
$394 Roundtrip, found 3 days ago
$394
Roundtrip
found 3 days ago
Select Delta flight, departing Sun, Nov 16 from Missoula to Key West, returning Thu, Dec 4, priced at $394 found 3 days ago
Delta
Sun, Nov 16 - Wed, Dec 10
MSO
Missoula
EYW
Key West
$399 Roundtrip, found 4 days ago
$399
Roundtrip
found 4 days ago
Select Delta flight, departing Sun, Nov 16 from Missoula to Key West, returning Wed, Dec 10, priced at $399 found 4 days ago
Delta
Wed, Nov 19 - Thu, Dec 4
MSO
Missoula
EYW
Key West
$404 Roundtrip, found 3 days ago
$404
Roundtrip
found 3 days ago
Select Delta flight, departing Wed, Nov 19 from Missoula to Key West, returning Thu, Dec 4, priced at $404 found 3 days ago
American Airlines
Wed, Feb 18 - Wed, Feb 25
MSO
Missoula
EYW
Key West
$409 Roundtrip, found 2 hours ago
$409
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Wed, Feb 18 from Missoula to Key West, returning Wed, Feb 25, priced at $409 found 2 hours ago
American Airlines
Tue, Nov 18 - Tue, Dec 9
MSO
Missoula
EYW
Key West
$414 Roundtrip, found 3 days ago
$414
Roundtrip
found 3 days ago
Select American Airlines flight, departing Tue, Nov 18 from Missoula to Key West, returning Tue, Dec 9, priced at $414 found 3 days ago
Delta
Sat, Jan 10 - Tue, Jan 13
MSO
Missoula
EYW
Key West
$421 Roundtrip, found 4 days ago
$421
Roundtrip
found 4 days ago
Select Delta flight, departing Sat, Jan 10 from Missoula to Key West, returning Tue, Jan 13, priced at $421 found 4 days ago
Delta
Tue, Feb 17 - Tue, Feb 24
MSO
Missoula
EYW
Key West
$423 Roundtrip, found 2 hours ago
$423
Roundtrip
found 2 hours ago
Select Delta flight, departing Tue, Feb 17 from Missoula to Key West, returning Tue, Feb 24, priced at $423 found 2 hours ago
United
Sat, Feb 21 - Mon, Mar 2
MSO
Missoula
EYW
Key West
$757 Roundtrip, found 2 hours ago
$757
Roundtrip
found 2 hours ago
Select United flight, departing Sat, Feb 21 from Missoula to Key West, returning Mon, Mar 2, priced at $757 found 2 hours ago

Alternative airports near Key West

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Key West Intl. EYW. Cheapest and Closest option available. Average driving time to city center is 8 minutes. Flights from $652
EYW
Key West Intl.
CheapestClosest
Average driving time to city center8 min
Flights from $652

Frequently asked questions

How much does a flight from Missoula Intl. Airport (MSO) to Key West Intl. Airport (EYW) cost?
Grab a cheap one-way flight from $181 or cheap return flight from $359 from Missoula Intl. Airport (MSO) to Key West Intl. Airport (EYW) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Missoula Intl. Airport (MSO) to Key West Intl. Airport (EYW)?
November is the cheapest month to fly from MSO to EYW. Planning your trip for the off-season is often the key to finding better fares.
What is the cheapest airline that flies from Missoula Intl. Airport (MSO) to Key West Intl. Airport (EYW)?
To find the cheapest airline that'll fly you from MSO to EYW, use Expedia's filter tool. Tailor your search based on what matters most to you, such as preferred carriers and seat class. You can then sort your results by "Price (lowest to highest)" to see the most affordable options first.
How many flights per day from Missoula Intl. Airport (MSO) to Key West Intl. Airport (EYW)?
There aren't any daily direct flights from Missoula Intl. Airport (MSO) to Key West Intl. Airport (EYW). But you can choose flights with layovers. Filter your search results on Expedia to include one or more stops, and you'll be on your way in no time.
What day of the week has the most flights from MSO to EYW?
Friday is typically the busiest day for flights, while Tuesday is often the quietest.* Remember that flight schedules can change depending on a range of factors, including the time of year and carrier.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Missoula Intl. Airport (MSO) to Key West Intl. Airport (EYW)?
To reach Key West Intl. Airport (EYW) on schedule, opt for a flight that leaves Missoula Intl. Airport (MSO) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Missoula Intl. Airport (MSO) to Key West Intl. Airport (EYW) last-minute?
Waiting until right before your break to book a ticket from MSO to EYW often results in higher prices. While you may come across some last-minute discounts, they aren't always guaranteed. Keep your travel schedule open for a better chance of getting a bargain.
Is it cheaper to book a MSO to EYW flight and hotel package?
You'll generally save money by booking a MSO to EYW flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's easy to manage it all in one convenient place. Once you've chosen your ideal flights and accommodations, you can add extras like activities, car rentals and tours.
Can I cancel or change the date of my flight from Missoula Intl. Airport (MSO) to Key West Intl. Airport (EYW)?
You can usually cancel or reschedule your MSO to EYW flight. However, if it's been more than 24 hours since booking, additional fees may apply. Refer to your airline's policies in your itinerary to see what changes are allowed and if any costs are involved. You'll also find more information on our Customer Service portal.

Travel information

Origin airport
Missoula Intl.
Destination airport
Key West Intl.
Airlines serving
American Airlines, Delta, United
Roundtrip price
$359
Distance
2353 mi

Book with confidence

Missoula to Key West Flights

The cheapest times to fly from Missoula to Key West

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Missoula to Key West are during the month of November. You can find some of the cheapest flights from Missoula to Key West with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Missoula to Key West

Sunday is one of the best days to book for cheap flights from Missoula to Key West: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Missoula to Key West

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Missoula to Key West in 2025. You can also book with separate airlines for your outbound and return journeys, from $181 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Missoula to Key West flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Missoula to Key West airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Missoula to Key West Flights

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*Available to One Key members.