$1,372 Cheap Flights from Pisa (PSA) to Santiago (SCL)

View $1,372 flight on Tue, Oct 21, 2025Opens in a new window

Popular airlines from Galileo Galilei Airport (PSA) to Santiago Intl. Airport (SCL)

    notification illustration

    Be in the know

    Get alerts if flight prices drop or rise*
    deals illustration

    Book smarter

    Save up to 30% on select hotels after you book a flight*
    trophy illustration

    Earn twice

    Earn your airline miles on top of our OneKeyCash
    Learn about One Key

Cheap Flights from Pisa to Santiago (PSA-SCL)

Prices were available within the past 7 days and start at $1,372 for one-way flights and for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frequently asked questions

How much does a flight from Galileo Galilei Airport (PSA) to Arturo Merino Benitez Airport (SCL) cost?
Snag a cheap one-way flight from $1,372 or cheap return flight from Galileo Galilei Airport (PSA) to Arturo Merino Benitez Airport (SCL) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Galileo Galilei Airport (PSA) to Arturo Merino Benitez Airport (SCL)?
is the least expensive month to fly from PSA to SCL. Traveling during quieter months is often the key to finding better fares.
What is the cheapest airline that flies from Galileo Galilei Airport (PSA) to Arturo Merino Benitez Airport (SCL)?
Expedia's filter tool lets you easily compare different airlines, flight durations and fares all in one place. Select your preferences, then sort by "Price (lowest to highest)" to see which carrier offers the cheapest PSA to SCL flight.
How many flights per day from Galileo Galilei Airport (PSA) to Arturo Merino Benitez Airport (SCL)?
Direct flights from Galileo Galilei Airport (PSA) to Arturo Merino Benitez Airport (SCL) aren't available daily, so you'll need to take a flight with a layover. Explore your options with Expedia's filters. Enter your travel dates and click on either "1 Stop" or "2+ Stops."
What day of the week has the most flights from PSA to SCL?
Friday is generally the busiest day for flights, while Tuesday is often the quietest.* Keep in mind that flight schedules can change depending on a number of factors, including the time of year and airline.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Galileo Galilei Airport (PSA) to Arturo Merino Benitez Airport (SCL)?
Select a flight from Galileo Galilei Airport (PSA) to Arturo Merino Benitez Airport (SCL) that takes off before 3 PM to reduce the risk of cancellations. Departures later than this are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Galileo Galilei Airport (PSA) to Arturo Merino Benitez Airport (SCL) last-minute?
Last-minute fares from PSA to SCL are usually more expensive. To lock in the cheapest rates, start searching for flights ahead of time. That being said, if you're flexible with your travel plans, you may find a cheap fare right before your journey.
Is it cheaper to book a PSA to SCL flight and hotel package?
Opting for a PSA to SCL flight and hotel package is generally cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your travels all in one place. Pick from our wide range of hotels and then add car rentals, activities and flights to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Galileo Galilei Airport (PSA) to Arturo Merino Benitez Airport (SCL)?
In most instances, you're able to cancel or reschedule your PSA to SCL flight. However, additional fees may apply, especially if your booking was made over 24 hours ago. Check your itinerary for the airline's guidelines and fees on flight changes, or if you want further details, go to our Customer Service portal.

Travel information

Origin airport
Galileo Galilei
Destination airport
Arturo Merino Benitez
Distance
7374 mi

Book with confidence

Pisa to Santiago Flights

The cheapest times to fly from Pisa to Santiago

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Pisa to Santiago are during the month of . You can find some of the cheapest flights from Pisa to Santiago with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Pisa to Santiago

Sunday is one of the best days to book for cheap flights from Pisa to Santiago: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Pisa to Santiago

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Pisa to Santiago in 2025. You can also book with separate airlines for your outbound and return journeys, from $1,372 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Pisa to Santiago flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Pisa to Santiago airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Pisa to Santiago Flights

Explore a world of travel with Expedia

*Available to One Key members.