$283 Cheap Flights from Panama City (PTY) to Mobile (MOB)

View $283 flight on Wed, Feb 18, 2026Opens in a new window

Popular airlines from Tocumen Intl. Airport (PTY) to Mobile Regional Airport (MOB)

Cheap Flights from Panama City to Mobile (PTY-MOB)

Prices were available within the past 7 days and start at $283 for one-way flights and $456 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Wed, Dec 10 - Tue, Jan 13
PTY
Panama City
MOB
Mobile
$456 Roundtrip, found 4 days ago
$456
Roundtrip
found 4 days ago
Select Delta flight, departing Wed, Dec 10 from Panama City to Mobile, returning Tue, Jan 13, priced at $456 found 4 days ago
United
Thu, May 28 - Tue, Jun 2
PTY
Panama City
MOB
Mobile
$456 Roundtrip, found 9 hours ago
$456
Roundtrip
found 9 hours ago
Select United flight, departing Thu, May 28 from Panama City to Mobile, returning Tue, Jun 2, priced at $456 found 9 hours ago
American Airlines
Wed, Dec 10 - Tue, Jan 13
PTY
Panama City
MOB
Mobile
$461 Roundtrip, found 4 days ago
$461
Roundtrip
found 4 days ago
Select American Airlines flight, departing Wed, Dec 10 from Panama City to Mobile, returning Tue, Jan 13, priced at $461 found 4 days ago
United
Thu, May 28 - Tue, Jun 2
PTY
Panama City
MOB
Mobile
$463 Roundtrip, found 9 hours ago
$463
Roundtrip
found 9 hours ago
Select United flight, departing Thu, May 28 from Panama City to Mobile, returning Tue, Jun 2, priced at $463 found 9 hours ago
United
Thu, May 28 - Tue, Jun 2
PTY
Panama City
MOB
Mobile
$471 Roundtrip, found 9 hours ago
$471
Roundtrip
found 9 hours ago
Select United flight, departing Thu, May 28 from Panama City to Mobile, returning Tue, Jun 2, priced at $471 found 9 hours ago
American Airlines
Thu, May 28 - Tue, Jun 2
PTY
Panama City
MOB
Mobile
$477 Roundtrip, found 9 hours ago
$477
Roundtrip
found 9 hours ago
Select American Airlines flight, departing Thu, May 28 from Panama City to Mobile, returning Tue, Jun 2, priced at $477 found 9 hours ago
American Airlines
Wed, Dec 10 - Sun, Jan 11
PTY
Panama City
MOB
Mobile
$482 Roundtrip, found 5 days ago
$482
Roundtrip
found 5 days ago
Select American Airlines flight, departing Wed, Dec 10 from Panama City to Mobile, returning Sun, Jan 11, priced at $482 found 5 days ago
United
Fri, May 29 - Wed, Jun 3
PTY
Panama City
MOB
Mobile
$485 Roundtrip, found 1 day ago
$485
Roundtrip
found 1 day ago
Select United flight, departing Fri, May 29 from Panama City to Mobile, returning Wed, Jun 3, priced at $485 found 1 day ago
United
Fri, May 29 - Wed, Jun 3
PTY
Panama City
MOB
Mobile
$485 Roundtrip, found 1 day ago
$485
Roundtrip
found 1 day ago
Select United flight, departing Fri, May 29 from Panama City to Mobile, returning Wed, Jun 3, priced at $485 found 1 day ago
American Airlines
Wed, Dec 10 - Sun, Jan 11
PTY
Panama City
MOB
Mobile
$490 Roundtrip, found 5 days ago
$490
Roundtrip
found 5 days ago
Select American Airlines flight, departing Wed, Dec 10 from Panama City to Mobile, returning Sun, Jan 11, priced at $490 found 5 days ago

Frequently asked questions

How much does a flight from Tocumen Intl. Airport (PTY) to Mobile Regional Airport (MOB) cost?
Secure a cheap one-way flight from $283 or cheap return flight from $456 from Tocumen Intl. Airport (PTY) to Mobile Regional Airport (MOB) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Tocumen Intl. Airport (PTY) to Mobile Regional Airport (MOB)?
The cheapest month to fly from PTY to MOB is December, when demand is low. Off-peak months are often when you'll find cheap fares for travel between these airports.
What is the cheapest airline that flies from Tocumen Intl. Airport (PTY) to Mobile Regional Airport (MOB)?
Expedia's filter tool lets you easily compare airlines, flight times and baggage options all in one place. Select your preferences, then sort by "Price (lowest to highest)" to see which carrier offers the cheapest PTY to MOB flight.
How many flights per day from Tocumen Intl. Airport (PTY) to Mobile Regional Airport (MOB)?
Nonstop flights from Tocumen Intl. Airport (PTY) to Mobile Regional Airport (MOB) aren't available daily, so you'll have to take a flight with a layover. Explore your options with Expedia's filters. Enter your dates and choose either "1 Stop" or "2+ Stops."
What day of the week has the most flights from PTY to MOB?
Generally you'll find the most flight options available on a Friday. Tuesdays are often the quietest.* But this can vary based on the airline, time of year and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Tocumen Intl. Airport (PTY) to Mobile Regional Airport (MOB)?
Book a flight from Tocumen Intl. Airport (PTY) to Mobile Regional Airport (MOB) that leaves before 3 PM to reduce the risk of cancellations. Departures later than this are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Tocumen Intl. Airport (PTY) to Mobile Regional Airport (MOB) last-minute?
Booking your ticket from PTY to MOB right before your getaway is usually more expensive. However, if there's some wiggle room with your departure times and dates, you could land a cheap last-minute fare.
Is it cheaper to book a PTY to MOB flight and hotel package?
Securing a PTY to MOB flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your trip all in one place. Select from our extensive range of accommodations and then add flights, activities and car rentals to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Tocumen Intl. Airport (PTY) to Mobile Regional Airport (MOB)?
If you booked your PTY to MOB flight in the last 24 hours, you may be able to modify or cancel it without fees. Depending on the airline and the type of ticket you purchased, additional charges may apply for changes after that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, visit our Customer Service portal if you want more information.

Travel information

Origin airport
Tocumen Intl.
Destination airport
Mobile Regional
Airlines serving
American Airlines, Delta, United
Roundtrip price
$456
Distance
1598 mi

Book with confidence

Panama City to Mobile Flights

The cheapest times to fly from Panama City to Mobile

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Panama City to Mobile are during the month of December. You can find some of the cheapest flights from Panama City to Mobile with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Panama City to Mobile

Sunday is one of the best days to book for cheap flights from Panama City to Mobile: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Panama City to Mobile

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Panama City to Mobile in 2025. You can also book with separate airlines for your outbound and return journeys, from $283 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Panama City to Mobile flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Panama City to Mobile airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Panama City to Mobile Flights

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*Available to One Key members.