$603 Cheap Flights from Raleigh (RDU) to Antofagasta (ANF)

View $603 flight on Wed, Apr 22, 2026Opens in a new window

Popular airlines from Raleigh-Durham International Airport (RDU) to Antofagasta (ANF-Cerro Moreno Intl.)

Cheap Flights from Raleigh to Antofagasta (RDU-ANF)

Prices were available within the past 7 days and start at $603 for one-way flights and for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Flights from Raleigh (RDU) to Antofagasta (ANF)
Origin airport
Raleigh - Durham Intl.
Destination airport
Cerro Moreno Intl.
Distance
4134 mi

Raleigh to Antofagasta Flights

The cheapest times to fly from Raleigh to Antofagasta

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Raleigh to Antofagasta are during the month of . You can find some of the cheapest flights from Raleigh to Antofagasta with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Raleigh to Antofagasta

Sunday is one of the best days to book for cheap flights from Raleigh to Antofagasta: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Raleigh to Antofagasta

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Raleigh to Antofagasta in 2025. You can also book with separate airlines for your outbound and return journeys, from $603 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Raleigh to Antofagasta flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Raleigh to Antofagasta airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Raleigh - Durham Intl. Airport (RDU) to Cerro Moreno Intl. Airport (ANF) cost?
Get a cheap one-way flight from $603 or cheap return flight from Raleigh - Durham Intl. Airport (RDU) to Cerro Moreno Intl. Airport (ANF) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Raleigh - Durham Intl. Airport (RDU) to Cerro Moreno Intl. Airport (ANF)?
is the cheapest month to fly from RDU to ANF. Timing your trip outside of the busy season is often the key to finding better deals on flights.
What is the cheapest airline that flies from Raleigh - Durham Intl. Airport (RDU) to Cerro Moreno Intl. Airport (ANF)?
Use the filters on Expedia to compare different airlines and find the most affordable carrier that'll fly you from RDU to ANF. Then, sort your results by "Price (lowest to highest)" to snag a good deal.
How many flights per day from Raleigh - Durham Intl. Airport (RDU) to Cerro Moreno Intl. Airport (ANF)?
You'll need to hop on a flight with a layover when traveling from Raleigh - Durham Intl. Airport (RDU) to Cerro Moreno Intl. Airport (ANF). Direct flights don't operate daily on this route. However, just filter your search to include one or two stops to discover an option that works for you.
What day of the week has the most flights from RDU to ANF?
Typically you'll find the most flight options available on a Friday. Tuesdays are often the quietest.* But this can vary based on the airline, time of year and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Raleigh - Durham Intl. Airport (RDU) to Cerro Moreno Intl. Airport (ANF)?
To avoid possible delays on the Raleigh - Durham Intl. Airport (RDU) to Cerro Moreno Intl. Airport (ANF) route, aim to fly before 3 PM. Later flights are 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Raleigh - Durham Intl. Airport (RDU) to Cerro Moreno Intl. Airport (ANF) last-minute?
Holding off until just before your departure to book a flight from RDU to ANF generally means paying more. While you might find some last-minute deals, they aren't always guaranteed. Be flexible with your itinerary for the best chance of snagging a bargain.
Is it cheaper to book a RDU to ANF flight and hotel package?
You'll generally save money by booking a RDU to ANF flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it's simple to manage everything in one place. After choosing your preferred flights and accommodations, consider adding extras such as activities, car rentals and tours.
Can I cancel or change the date of my flight from Raleigh - Durham Intl. Airport (RDU) to Cerro Moreno Intl. Airport (ANF)?
In most cases, you can cancel or modify your RDU to ANF flight. However, additional charges may apply, especially if you booked more than 24 hours ago. Check your itinerary for the airline's fees and policies on flight changes, or if you'd like more information, go to our Customer Service portal.

Explore a world of travel with Expedia

*Available to One Key members.