$424 Cheap Flights from Roanoke (ROA) to Palermo (PMO)

View $424 flight on Thu, Feb 5, 2026Opens in a new window

Popular airlines from Roanoke Regional Airport (ROA) to Punta Raisi Airport (PMO)

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Cheap Flights from Roanoke to Palermo (ROA-PMO)

Prices were available within the past 7 days and start at $424 for one-way flights and $494 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

United
Sat, Jan 24 - Fri, Feb 6
ROA
Roanoke
PMO
Palermo
$494 Roundtrip, found 2 days ago
$494
Roundtrip
found 2 days ago
Select United flight, departing Sat, Jan 24 from Roanoke to Palermo, returning Fri, Feb 6, priced at $494 found 2 days ago
United
Sat, Jan 31 - Mon, Feb 16
ROA
Roanoke
PMO
Palermo
$496 Roundtrip, found 2 days ago
$496
Roundtrip
found 2 days ago
Select United flight, departing Sat, Jan 31 from Roanoke to Palermo, returning Mon, Feb 16, priced at $496 found 2 days ago
United
Sat, Jan 17 - Sat, Jan 31
ROA
Roanoke
PMO
Palermo
$497 Roundtrip, found 2 days ago
$497
Roundtrip
found 2 days ago
Select United flight, departing Sat, Jan 17 from Roanoke to Palermo, returning Sat, Jan 31, priced at $497 found 2 days ago
United
Wed, Jan 14 - Sat, Jan 31
ROA
Roanoke
PMO
Palermo
$498 Roundtrip, found 2 days ago
$498
Roundtrip
found 2 days ago
Select United flight, departing Wed, Jan 14 from Roanoke to Palermo, returning Sat, Jan 31, priced at $498 found 2 days ago
United
Fri, Jan 9 - Thu, Jan 22
ROA
Roanoke
PMO
Palermo
$509 Roundtrip, found 2 days ago
$509
Roundtrip
found 2 days ago
Select United flight, departing Fri, Jan 9 from Roanoke to Palermo, returning Thu, Jan 22, priced at $509 found 2 days ago
Lufthansa
Sat, Jan 10 - Thu, Jan 22
ROA
Roanoke
PMO
Palermo
$515 Roundtrip, found 2 days ago
$515
Roundtrip
found 2 days ago
Select Lufthansa flight, departing Sat, Jan 10 from Roanoke to Palermo, returning Thu, Jan 22, priced at $515 found 2 days ago
Lufthansa
Thu, Jan 8 - Thu, Jan 22
ROA
Roanoke
PMO
Palermo
$528 Roundtrip, found 2 days ago
$528
Roundtrip
found 2 days ago
Select Lufthansa flight, departing Thu, Jan 8 from Roanoke to Palermo, returning Thu, Jan 22, priced at $528 found 2 days ago
Air France
Sun, Feb 1 - Fri, Feb 13
ROA
Roanoke
PMO
Palermo
$566 Roundtrip, found 2 days ago
$566
Roundtrip
found 2 days ago
Select Air France flight, departing Sun, Feb 1 from Roanoke to Palermo, returning Fri, Feb 13, priced at $566 found 2 days ago
KLM
Wed, Dec 31 - Mon, Jan 19
ROA
Roanoke
PMO
Palermo
$566 Roundtrip, found 2 days ago
$566
Roundtrip
found 2 days ago
Select KLM flight, departing Wed, Dec 31 from Roanoke to Palermo, returning Mon, Jan 19, priced at $566 found 2 days ago
Delta
Wed, Jan 28 - Wed, Feb 11
ROA
Roanoke
PMO
Palermo
$583 Roundtrip, found 2 days ago
$583
Roundtrip
found 2 days ago
Select Delta flight, departing Wed, Jan 28 from Roanoke to Palermo, returning Wed, Feb 11, priced at $583 found 2 days ago

Frequently asked questions

How much does a flight from Roanoke Regional Airport (ROA) to Punta Raisi Airport (PMO) cost?
Grab a cheap one-way flight from $424 or cheap return flight from $494 from Roanoke Regional Airport (ROA) to Punta Raisi Airport (PMO) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Roanoke Regional Airport (ROA) to Punta Raisi Airport (PMO)?
January is the least expensive month to fly from ROA to PMO. Avoiding peak travel times is often the key to scoring lower fares.
What is the cheapest airline that flies from Roanoke Regional Airport (ROA) to Punta Raisi Airport (PMO)?
Expedia's filter tool lets you easily compare different airlines, flight durations and fares all in one place. Tailor the search to your trip, then sort by "Price (lowest to highest)" to find the carrier with the cheapest ROA to PMO flight.
How many flights per day from Roanoke Regional Airport (ROA) to Punta Raisi Airport (PMO)?
You'll have to hop on a flight with a layover if you're traveling from Roanoke Regional Airport (ROA) to Punta Raisi Airport (PMO). There are no daily direct flights on this route. However, just filter your search to include one or two stops to find the best option for your trip.
What day of the week has the most flights from ROA to PMO?
You'll generally find Tuesday the quietest day for flights, while Fridays are often the busiest.* However this can vary from season to season and during public holidays or peak travel times.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Roanoke Regional Airport (ROA) to Punta Raisi Airport (PMO)?
To touch down at Punta Raisi Airport (PMO) without delays, select a flight that leaves Roanoke Regional Airport (ROA) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Roanoke Regional Airport (ROA) to Punta Raisi Airport (PMO) last-minute?
Holding off until right before your break to book a ticket from ROA to PMO generally means paying more. While it's possible to find some last-minute offers, they're not always guaranteed. Be flexible with your travel plans for the best chance of landing a bargain.
Is it cheaper to book a ROA to PMO flight and hotel package?
Opting for a ROA to PMO flight and hotel package is typically cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your trip in one place. Select from our impressive range of stays and then add activities, car rentals and flights to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Roanoke Regional Airport (ROA) to Punta Raisi Airport (PMO)?
In most cases, you're able to reschedule or cancel your ROA to PMO flight. However, there may be additional fees, especially if you booked over 24 hours ago. Check your itinerary for the airline's rules and fees on flight changes, or if you need more information, go to our Customer Service portal.

Travel information

Origin airport
Roanoke Regional
Destination airport
Punta Raisi
Airlines serving
Air France, American Airlines, KLM, Lufthansa, United
Roundtrip price
$493
Distance
4839 mi

Book with confidence

Roanoke to Palermo Flights

The cheapest times to fly from Roanoke to Palermo

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Roanoke to Palermo are during the month of January. You can find some of the cheapest flights from Roanoke to Palermo with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Roanoke to Palermo

Sunday is one of the best days to book for cheap flights from Roanoke to Palermo: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Roanoke to Palermo

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Roanoke to Palermo in 2025. You can also book with separate airlines for your outbound and return journeys, from $424 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Roanoke to Palermo flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Roanoke to Palermo airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Roanoke to Palermo Flights

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*Available to One Key members.