$180 Cheap Flights from San Antonio (SAT) to Tupelo (TUP)

View $180 flight on Fri, Oct 31, 2025Opens in a new window

Popular airlines from San Antonio International Airport (SAT) to Tupelo, MS (TUP-Tupelo Regional)

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Cheap Flights from San Antonio to Tupelo (SAT-TUP)

Prices were available within the past 7 days and start at $180 for one-way flights and $364 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

United
Thu, Nov 27 - Tue, Dec 16
SAT
San Antonio
TUP
Tupelo
$364 Roundtrip, found 4 days ago
$364
Roundtrip
found 4 days ago
Select United flight, departing Thu, Nov 27 from San Antonio to Tupelo, returning Tue, Dec 16, priced at $364 found 4 days ago
American Airlines
Tue, Dec 2 - Thu, Dec 4
SAT
San Antonio
TUP
Tupelo
$373 Roundtrip, found 2 days ago
$373
Roundtrip
found 2 days ago
Select American Airlines flight, departing Tue, Dec 2 from San Antonio to Tupelo, returning Thu, Dec 4, priced at $373 found 2 days ago
United
Wed, Dec 3 - Sat, Dec 13
SAT
San Antonio
TUP
Tupelo
$374 Roundtrip, found 4 days ago
$374
Roundtrip
found 4 days ago
Select United flight, departing Wed, Dec 3 from San Antonio to Tupelo, returning Sat, Dec 13, priced at $374 found 4 days ago
United
Tue, Dec 2 - Fri, Dec 12
SAT
San Antonio
TUP
Tupelo
$391 Roundtrip, found 4 days ago
$391
Roundtrip
found 4 days ago
Select United flight, departing Tue, Dec 2 from San Antonio to Tupelo, returning Fri, Dec 12, priced at $391 found 4 days ago
American Airlines
Tue, Dec 2 - Thu, Dec 4
SAT
San Antonio
TUP
Tupelo
$399 Roundtrip, found 2 days ago
$399
Roundtrip
found 2 days ago
Select American Airlines flight, departing Tue, Dec 2 from San Antonio to Tupelo, returning Thu, Dec 4, priced at $399 found 2 days ago
United
Thu, Nov 27 - Thu, Dec 18
SAT
San Antonio
TUP
Tupelo
$399 Roundtrip, found 4 days ago
$399
Roundtrip
found 4 days ago
Select United flight, departing Thu, Nov 27 from San Antonio to Tupelo, returning Thu, Dec 18, priced at $399 found 4 days ago
United
Mon, Nov 24 - Sat, Dec 6
SAT
San Antonio
TUP
Tupelo
$403 Roundtrip, found 4 days ago
$403
Roundtrip
found 4 days ago
Select United flight, departing Mon, Nov 24 from San Antonio to Tupelo, returning Sat, Dec 6, priced at $403 found 4 days ago
United
Sat, Nov 15 - Thu, Dec 4
SAT
San Antonio
TUP
Tupelo
$404 Roundtrip, found 4 days ago
$404
Roundtrip
found 4 days ago
Select United flight, departing Sat, Nov 15 from San Antonio to Tupelo, returning Thu, Dec 4, priced at $404 found 4 days ago
United
Mon, Nov 24 - Thu, Dec 11
SAT
San Antonio
TUP
Tupelo
$411 Roundtrip, found 4 days ago
$411
Roundtrip
found 4 days ago
Select United flight, departing Mon, Nov 24 from San Antonio to Tupelo, returning Thu, Dec 11, priced at $411 found 4 days ago
United
Fri, Nov 7 - Mon, Nov 24
SAT
San Antonio
TUP
Tupelo
$420 Roundtrip, found 4 days ago
$420
Roundtrip
found 4 days ago
Select United flight, departing Fri, Nov 7 from San Antonio to Tupelo, returning Mon, Nov 24, priced at $420 found 4 days ago

Alternative airports near Tupelo

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Tupelo Regional TUP. Cheapest and Closest option available. Average driving time to city center is 8 minutes. Flights from $460
TUP
Tupelo Regional
CheapestClosest
Average driving time to city center8 min
Flights from $460

Frequently asked questions

How much does a flight from San Antonio Intl. Airport (SAT) to Tupelo Regional Airport (TUP) cost?
Grab a cheap one-way flight from $180 or cheap return flight from $364 from San Antonio Intl. Airport (SAT) to Tupelo Regional Airport (TUP) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from San Antonio Intl. Airport (SAT) to Tupelo Regional Airport (TUP)?
November is the most affordable month to fly from SAT to TUP. Traveling outside of peak seasons is often the key to finding better deals on flights.
What is the cheapest airline that flies from San Antonio Intl. Airport (SAT) to Tupelo Regional Airport (TUP)?
Expedia's filter tool lets you easily compare different airlines, travel time and fares all in one place. Customize the search to your preferences, then sort by "Price (lowest to highest)" to find the carrier with the cheapest SAT to TUP flight.
How many flights per day from San Antonio Intl. Airport (SAT) to Tupelo Regional Airport (TUP)?
You'll have to book a flight with a layover if you're traveling from San Antonio Intl. Airport (SAT) to Tupelo Regional Airport (TUP). There are no daily direct flights on this route. However, just filter your search to include one or two stops to find the best option for your trip.
What day of the week has the most flights from SAT to TUP?
You'll generally find Tuesday the quietest day for flights, while Fridays are often the busiest.* However this can change from season to season and during public holidays or peak travel times.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from San Antonio Intl. Airport (SAT) to Tupelo Regional Airport (TUP)?
To avoid possible delays on the San Antonio Intl. Airport (SAT) to Tupelo Regional Airport (TUP) route, aim to travel before 3 PM. Departures after this hour have a 22% higher chance of cancellation.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from San Antonio Intl. Airport (SAT) to Tupelo Regional Airport (TUP) last-minute?
Holding off until right before your break to book your flight from SAT to TUP generally means paying more. While you might find some last-minute deals, there's no guarantee. Allow some flexibility in your schedule to maximize your chances of scoring a bargain.
Is it cheaper to book a SAT to TUP flight and hotel package?
You can save money by booking a SAT to TUP flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's easy to manage it all in one place. Once you've selected your preferred accommodations and flights, consider adding extras such as tours, car rentals and activities.
Can I cancel or change the date of my flight from San Antonio Intl. Airport (SAT) to Tupelo Regional Airport (TUP)?
It's generally possible to reschedule or cancel your SAT to TUP flight. However, for bookings made more than 24 hours ago, additional fees may apply. Check your airline's policies in your itinerary to see what changes are allowed and if any costs are involved. You'll also find further details on our Customer Service portal.

Travel information

Origin airport
San Antonio Intl.
Destination airport
Tupelo Regional
Roundtrip price
$364
Distance
656 mi

Book with confidence

San Antonio to Tupelo Flights

The cheapest times to fly from San Antonio to Tupelo

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from San Antonio to Tupelo are during the month of November. You can find some of the cheapest flights from San Antonio to Tupelo with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from San Antonio to Tupelo

Sunday is one of the best days to book for cheap flights from San Antonio to Tupelo: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from San Antonio to Tupelo

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from San Antonio to Tupelo in 2025. You can also book with separate airlines for your outbound and return journeys, from $180 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap San Antonio to Tupelo flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your San Antonio to Tupelo airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

San Antonio to Tupelo Flights

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*Available to One Key members.