Cheap Flights from Knoxville (TYS) to Mesa (AZA)

Popular airlines from McGhee Tyson Airport (TYS) to Phoenix - Mesa Gateway Airport (AZA)

Alternative airports near Mesa

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Sky Harbor Intl. PHX. Cheapest option available. Average driving time to city center is 18 minutes. Flights from $359
PHX
Sky Harbor Intl.
Cheapest
Average driving time to city center18 min
Flights from $359

Frequently asked questions

How much does a flight from McGhee Tyson Airport (TYS) to Phoenix - Mesa Gateway Airport (AZA) cost?
Get a cheap one-way flight or cheap return flight from McGhee Tyson Airport (TYS) to Phoenix - Mesa Gateway Airport (AZA) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from McGhee Tyson Airport (TYS) to Phoenix - Mesa Gateway Airport (AZA)?
Planning your trip for is a good way to save, as it's the cheapest month for flights between TYS and AZA. You'll usually find the lowest fares during the off-season.
What is the cheapest airline that flies from McGhee Tyson Airport (TYS) to Phoenix - Mesa Gateway Airport (AZA)?
To find the cheapest airline flying from TYS to AZA, use Expedia's filter tool. Customize your search based on what's important to you, such as preferred carriers and cabin class. You can then sort your results by "Price (lowest to highest)" to see the cheapest fares upfront.
How many flights per day from McGhee Tyson Airport (TYS) to Phoenix - Mesa Gateway Airport (AZA)?
Nonstop flights from McGhee Tyson Airport (TYS) to Phoenix - Mesa Gateway Airport (AZA) aren't available daily, so you'll need to take a flight with a layover. Explore your options with our filter tool. Enter your travel dates and choose either "1 Stop" or "2+ Stops."
What day of the week has the most flights from TYS to AZA?
Typically you'll have the most choice when it comes to flights on a Friday. Tuesdays are often the quietest.* But this can vary based on the season, airline and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from McGhee Tyson Airport (TYS) to Phoenix - Mesa Gateway Airport (AZA)?
To avoid potential delays on the McGhee Tyson Airport (TYS) to Phoenix - Mesa Gateway Airport (AZA) route, fly before 3 PM. Flights after this time have a 22% higher chance of cancellation.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for Phoenix from McGhee Tyson Airport (TYS)?
Explore your flight options from McGhee Tyson Airport (TYS) to Sky Harbor Intl. Airport (PHX). This is the only Phoenix airport you can touch down at if you're taking a direct flight.
Is it cheaper to buy a plane ticket from McGhee Tyson Airport (TYS) to Phoenix - Mesa Gateway Airport (AZA) last-minute?
Waiting until just before your departure to book your flight from TYS to AZA often results in higher prices. Although you may find some last-minute offers, they're not always guaranteed. Be flexible with your travel plans to maximize your chances of scoring a bargain.
Is it cheaper to book a TYS to AZA flight and hotel package?
You'll generally save money by booking a TYS to AZA flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it's easy to manage everything in one convenient place. After selecting your ideal flights and accommodations, consider adding extras including car rentals, activities and tours.
Can I cancel or change the date of my flight from McGhee Tyson Airport (TYS) to Phoenix - Mesa Gateway Airport (AZA)?
Generally, it's possible to cancel or reschedule your TYS to AZA flight. However, if it's been more than 24 hours since booking, additional charges may apply. Check your airline's policies in your itinerary to see what changes are possible and whether any costs are involved. You'll also find more information on our Customer Service portal.

Travel information

Origin airport
McGhee Tyson
Destination airport
Phoenix - Mesa Gateway
Distance
1579 mi

Book with confidence

Knoxville to Mesa Flights

The cheapest times to fly from Knoxville to Mesa

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Knoxville to Mesa are during the month of . You can find some of the cheapest flights from Knoxville to Mesa with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Knoxville to Mesa

Sunday is one of the best days to book for cheap flights from Knoxville to Mesa: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Knoxville to Mesa

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Knoxville to Mesa in 2025. You can also book with separate airlines for your outbound and return journeys, from one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Knoxville to Mesa flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Knoxville to Mesa airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Knoxville to Mesa Flights

Explore a world of travel with Expedia

*Available to One Key members.