$426 Cheap Flights from Quito (UIO) to Indianapolis (IND)

View $426 flight on Tue, Dec 16, 2025Opens in a new window

Popular airlines from Mariscal Sucre Intl. Airport (UIO) to Indianapolis Intl. Airport (IND)

Cheap Flights from Quito to Indianapolis (UIO-IND)

Prices were available within the past 7 days and start at $426 for one-way flights and $693 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

United
Tue, Apr 21 - Tue, Apr 28
UIO
Quito
IND
Indianapolis
$693 Roundtrip, found 5 days ago
$693
Roundtrip
found 5 days ago
Select United flight, departing Tue, Apr 21 from Quito to Indianapolis, returning Tue, Apr 28, priced at $693 found 5 days ago
United
Mon, Apr 20 - Mon, Apr 27
UIO
Quito
IND
Indianapolis
$712 Roundtrip, found 5 days ago
$712
Roundtrip
found 5 days ago
Select United flight, departing Mon, Apr 20 from Quito to Indianapolis, returning Mon, Apr 27, priced at $712 found 5 days ago
Delta
Sun, Apr 19 - Sun, Apr 26
UIO
Quito
IND
Indianapolis
$757 Roundtrip, found 5 days ago
$757
Roundtrip
found 5 days ago
Select Delta flight, departing Sun, Apr 19 from Quito to Indianapolis, returning Sun, Apr 26, priced at $757 found 5 days ago
Delta
Sun, Apr 19 - Thu, Apr 30
UIO
Quito
IND
Indianapolis
$762 Roundtrip, found 5 days ago
$762
Roundtrip
found 5 days ago
Select Delta flight, departing Sun, Apr 19 from Quito to Indianapolis, returning Thu, Apr 30, priced at $762 found 5 days ago
avianca
Fri, Apr 24 - Sat, Apr 25
UIO
Quito
IND
Indianapolis
$770 Roundtrip, found 5 days ago
$770
Roundtrip
found 5 days ago
Select avianca flight, departing Fri, Apr 24 from Quito to Indianapolis, returning Sat, Apr 25, priced at $770 found 5 days ago
American Airlines
Wed, Sep 16 - Tue, Sep 22
UIO
Quito
IND
Indianapolis
$773 Roundtrip, found 1 day ago
$773
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Sep 16 from Quito to Indianapolis, returning Tue, Sep 22, priced at $773 found 1 day ago
American Airlines
Wed, Sep 16 - Tue, Sep 22
UIO
Quito
IND
Indianapolis
$778 Roundtrip, found 1 day ago
$778
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Sep 16 from Quito to Indianapolis, returning Tue, Sep 22, priced at $778 found 1 day ago
avianca
Mon, Apr 20 - Fri, Apr 24
UIO
Quito
IND
Indianapolis
$778 Roundtrip, found 5 days ago
$778
Roundtrip
found 5 days ago
Select avianca flight, departing Mon, Apr 20 from Quito to Indianapolis, returning Fri, Apr 24, priced at $778 found 5 days ago
American Airlines
Thu, Sep 10 - Sun, Sep 13
UIO
Quito
IND
Indianapolis
$785 Roundtrip, found 4 days ago
$785
Roundtrip
found 4 days ago
Select American Airlines flight, departing Thu, Sep 10 from Quito to Indianapolis, returning Sun, Sep 13, priced at $785 found 4 days ago
Copa
Mon, Nov 3 - Fri, Nov 7
UIO
Quito
IND
Indianapolis
$807 Roundtrip, found 6 hours ago
$807
Roundtrip
found 6 hours ago
Select Copa flight, departing Mon, Nov 3 from Quito to Indianapolis, returning Fri, Nov 7, priced at $807 found 6 hours ago

Frequently asked questions

How much does a flight from Mariscal Sucre Intl. Airport (UIO) to Indianapolis Intl. Airport (IND) cost?
Get a cheap one-way flight from $426 or cheap return flight from $693 from Mariscal Sucre Intl. Airport (UIO) to Indianapolis Intl. Airport (IND) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Mariscal Sucre Intl. Airport (UIO) to Indianapolis Intl. Airport (IND)?
Planning your getaway for April is a great way to save, as it's the cheapest month for flights between UIO and IND. You'll usually find the lowest prices during off-peak months.
What is the cheapest airline that flies from Mariscal Sucre Intl. Airport (UIO) to Indianapolis Intl. Airport (IND)?
To find the cheapest airline that'll fly you from UIO to IND, use Expedia's filter tool. Customize your search based on what matters most to you, such as preferred carriers and flight duration. You can then sort your results by "Price (lowest to highest)" to see the cheapest flights first.
How many flights per day from Mariscal Sucre Intl. Airport (UIO) to Indianapolis Intl. Airport (IND)?
Direct flights from Mariscal Sucre Intl. Airport (UIO) to Indianapolis Intl. Airport (IND) aren't available daily, so you'll have to take a flight with a layover. Explore your options with Expedia's filter tool. Enter your travel dates and choose either "1 Stop" or "2+ Stops."
What day of the week has the most flights from UIO to IND?
Usually you'll find the most flight options available on a Friday. Tuesdays tend to be the quietest.* However, this can vary depending on the season, carrier and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Mariscal Sucre Intl. Airport (UIO) to Indianapolis Intl. Airport (IND)?
To avoid potential delays on the Mariscal Sucre Intl. Airport (UIO) to Indianapolis Intl. Airport (IND) route, fly before 3 PM. Later departures have a 22% higher chance of cancellation.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Mariscal Sucre Intl. Airport (UIO) to Indianapolis Intl. Airport (IND) last-minute?
Waiting until right before your break to book a ticket from UIO to IND often results in higher prices. While it's possible to find some last-minute deals, they're not always guaranteed. Be flexible with your itinerary for a better chance of snagging a bargain.
Is it cheaper to book an UIO to IND flight and hotel package?
You'll generally save money by securing an UIO to IND flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's simple to manage everything in one place. Once you've selected your ideal accommodations and flights, consider adding extras like activities, car rentals and tours.
Can I cancel or change the date of my flight from Mariscal Sucre Intl. Airport (UIO) to Indianapolis Intl. Airport (IND)?
If you booked your UIO to IND flight in the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of fare you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, go to our Customer Service portal for more information.

Travel information

Origin airport
Mariscal Sucre Intl.
Destination airport
Indianapolis Intl.
Airlines serving
American Airlines, Delta, LATAM Airlines Group, United
Roundtrip price
$692
Distance
2797 mi

Book with confidence

Quito to Indianapolis Flights

The cheapest times to fly from Quito to Indianapolis

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Quito to Indianapolis are during the month of April. You can find some of the cheapest flights from Quito to Indianapolis with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Quito to Indianapolis

Sunday is one of the best days to book for cheap flights from Quito to Indianapolis: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Quito to Indianapolis

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Quito to Indianapolis in 2025. You can also book with separate airlines for your outbound and return journeys, from $426 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Quito to Indianapolis flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Quito to Indianapolis airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Quito to Indianapolis Flights

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*Available to One Key members.