$239 Cheap American Airlines flights Des Moines (DSM) to Chattanooga (CHA)

You'll find affordable return American Airlines flights from $249 from DSM to CHA by filtering your results from "Price (lowest to highest)" on Expedia. Or look for bargains from $239 for a one-way trip.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Look for cheap American Airlines flights from Des Moines Intl. Airport (DSM) to Chattanooga Metropolitan Airport (CHA) one to three months before your departure. Travelers who book domestic flights 34 to 86 days in advance can save 25% compared to those who book just 6 to 12 days ahead. No matter the fare class and itinerary, the best day to book a domestic flight is usually Sunday and the most expensive tends to be Monday. Passengers who book on a Sunday can save 6% on average compared to those who book their travel on a Monday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

Sort your results by "Morning" and "Early Morning" to find the earliest flights from DSM to CHA. Taking off early means you're less likely to experience cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.