$414 Cheap American Airlines flights Detroit (DTW) to Manchester (MAN)

Scoring cheap one-way American Airlines flights from DTW to MAN from $414 on Expedia couldn't be easier — just filter by "Price (lowest to highest)." Alternatively, check out our budget-friendly round-trip fares from $634 for your next adventure.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Landing the best American Airlines deals from DTW to MAN often comes down to timing. You can save 17% on international flights when you book 18 to 29 days before takeoff instead of four to five months ahead. Better yet, you can pocket 17% on average by buying your fare on a Sunday compared to a Friday, which is usually the most expensive day to book.* It's a good idea to start searching for flights about one month before your departure date.*Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

Search American Airlines's earliest flights from DTW to MAN by selecting our "Morning" and "Early Morning" filters. Not only will you get to where you're going sooner, early departures are also 20% less likely to be canceled.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.