$151 Cheap American Airlines flights Syracuse (SYR) to Chicago (ORD)

You'll discover affordable return American Airlines flights from $209 from SYR to ORD by organizing your results from "Price (lowest to highest)" on Expedia. Or look for bargains from $151 for a one-way journey.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Begin your search one to three months ahead of your departure date to get cheap fares on American Airlines flights from Hancock Intl. Airport (SYR) to O'Hare Intl. Airport (ORD). You can save 25% by booking your domestic flight 34 to 86 days in advance compared to last-minute reservations made 6 to 12 days out. You could also reduce costs by buying your fare on a Sunday, as it's 6% cheaper on average than a Monday, the most expensive day to book.* Nail your timing, and you can enjoy significant savings on domestic flights.*Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

The earliest American Airlines flight from SYR to ORD departs at 7:26AM UTC-5, arriving at 8:48AM UTC-6. If you prefer to set off later in the day, the last American Airlines flight leaves SYR at 12:59PM UTC-5 and touches down at ORD at 2:05PM UTC-6. Flying early is generally a smart option as morning and mid-morning flights tend to experience fewer cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.