$141 Cheap American Airlines flights Harrisburg (MDT) to Chicago (ORD)

Landing cheap one-way American Airlines flights from MDT to ORD from $141 on Expedia is simple — just filter by “Price (lowest to highest).” Alternatively, check out our affordable round-trip fares from $209 for your next break.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Look for one-way or round-trip flights to Chicago in January or February. You could find lower fares with American Airlines during these quieter months.

Search for cheap American Airlines flights from Harrisburg Intl. Airport (MDT) to O’Hare Intl. Airport (ORD) one to three months prior to your departure. Travelers who book domestic flights 34 to 86 days in advance can save 25% compared to those who book just 6 to 12 days ahead. No matter the fare class and itinerary, the best day of the week to book a domestic flight is generally Sunday and the most expensive tends to be Monday. Passengers who book on a Sunday can save 6% on average compared to those who book on a Monday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC’s global airline sales database.

American Airlines operates direct flights from Harrisburg Intl. Airport (MDT) to O’Hare Intl. Airport (ORD), with 13 departures each week. Just apply the “Nonstop” and “Airline” filters during your search on Expedia to find all direct American Airlines flights to ORD.

Leave Harrisburg Intl. Airport (MDT) for O’Hare Intl. Airport (ORD) on a direct American Airlines flight, and you’ll be in the sky for around 2h 27m.

American Airlines has the most flights from Harrisburg Intl. Airport (MDT) to O’Hare Intl. Airport (ORD) on Thursday. With up to 2 daily departures, you’ll get the most options and flexibility on this day.

The first flight from MDT to ORD with American Airlines departs at 7:41AM UTC-5. You’ll land at 9:10AM UTC-6. The final American Airlines flight of the day takes off at 12:30PM UTC-5 and arrives at 1:57PM UTC-6. With approximately 20% fewer cancellations for morning and mid-morning departures, heading out early is often the smartest choice.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.

American Airlines flights from Harrisburg Intl. Airport (MDT) to Chicago touch down at O’Hare Intl. Airport (ORD). This is the main gateway here.

You’ll most likely be flying on an Embraer RJ145 for your American Airlines flight from Harrisburg Intl. Airport (MDT) to O’Hare Intl. Airport (ORD). However, you could be switched to an alternative aircraft if there are operational changes.

Depending on the type of ticket you purchased, a fee will generally apply if you cancel or change your flight more than 24 hours after it’s been confirmed. To secure flexible fares, select our “Changes included” and “No cancel fee” boxes when searching for flights. To learn more about canceling or changing your reservation, head to “Trips,” select your flight and click on “Manage Booking.”