$119 Cheap American Airlines flights St. Louis (STL) to Amarillo (AMA)

Scoring cheap one-way American Airlines flights from STL to AMA from $119 on Expedia is simple --- just filter by "Price (lowest to highest)." Or check out our affordable round-trip fares from $236 for your next exciting getaway.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Look for cheap American Airlines flights from Lambert-St. Louis Intl. Airport (STL) to Rick Husband Amarillo Intl. Airport (AMA) one to three months prior to your day of departure. Travelers who book domestic flights 34 to 86 days in advance can save 25% compared to those who book just 6 to 12 days ahead. No matter the fare type and itinerary, the best day of the week to book a domestic flight is usually Sunday and the most expensive day is typically Monday. Passengers who book on a Sunday can save 6% on average compared to those who book on a Monday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

To find the earliest departures from STL to AMA with American Airlines, filter your search by "Morning" and "Early Morning." Booking an early flight generally means you'll experience fewer cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.