$271 Cheap American Airlines flights Manhattan (MHK) to Chicago (ORD)

Make use of the "Price (lowest to highest)" filter on Expedia to find cheap American Airlines return flights from $361 from MHK to ORD. Affordable one-way fares from $271 are also available.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Search for affordable American Airlines flights from Manhattan Regional Airport (MHK) to O'Hare Intl. Airport (ORD) one to three months before your departure date. Travelers who book domestic flights 34 to 86 days in advance can save 25% compared to those who book just 6 to 12 days ahead. No matter the fare type and journey, the best day of the week to book a domestic flight is generally Sunday and the most expensive tends to be Monday. Passengers who book on a Sunday can save 6% on average compared to those who book on a Monday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

The earliest flight from MHK to ORD with American Airlines departs at 5:00AM UTC-6. You'll touch down at 6:57AM UTC-6. The final American Airlines flight of the day takes off at 12:41PM UTC-6 and arrives at 2:20PM UTC-6. With approximately 20% fewer cancellations for departures before midday, starting your travel day early is usually the smartest option.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.