$161 Cheap American Airlines flights Minneapolis (MSP) to Harrisburg (MDT)

You can discover budget-friendly return American Airlines flights from $249 from MSP to MDT by filtering your results from "Price (lowest to highest)" on Expedia. Or search for options from $161 for a one-way trip.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Begin your search one to three months ahead of your travel date to find cheaper fares on American Airlines flights from Minneapolis - St. Paul Intl. Airport (MSP) to Harrisburg Intl. Airport (MDT). You can save 25% by booking your domestic flight 34 to 86 days in advance compared to last-minute reservations made 6 to 12 days out. You could also reduce costs by buying your fare on a Sunday, as it's 6% cheaper on average than a Monday, the most expensive day to book.* Nail your timing, and you can enjoy significant savings on domestic flights.*Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

Sort your results by "Morning" and "Early Morning" to find the earliest flights from MSP to MDT. Taking off early means flight cancellations are less likely.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.