$117 Cheap American Airlines flights Minneapolis (MSP) to Indianapolis (IND)

Landing cheap one-way American Airlines flights from MSP to IND from $117 on Expedia is a cinch --- just filter by "Price (lowest to highest)." Or check out our affordable round-trip fares from $181 for your next exciting adventure.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Look for cheap American Airlines flights from Minneapolis - St. Paul Intl. Airport (MSP) to Indianapolis Intl. Airport (IND) one to three months prior to your day of departure. Travelers who book domestic flights 34 to 86 days in advance can save 25% compared to those who book just 6 to 12 days ahead. No matter the fare class and journey, the ideal day to book a domestic flight is usually Sunday and the most expensive tends to be Monday. Passengers who book on a Sunday can save 6% on average compared to those who book their travel on a Monday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

Find American Airlines's earliest flights from MSP to IND by using the "Early Morning" and "Morning" filters. Not only will you arrive sooner, early departures also have a 20% less chance of being canceled.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.