$125 Cheap American Airlines flights Minneapolis (MSP) to Houston (HOU)

Set the “Price (lowest to highest)” filter on Expedia to search for cheap American Airlines return flights from $234 from MSP to HOU. Affordable one-way tickets from $125 are available as well.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

American Airlines flights to Houston tend to be more affordable in the quieter months of November and February. Whether you need a one-way or a return ticket, you could find a better deal then.

Look for cheap American Airlines flights from Minneapolis - St. Paul Intl. Airport (MSP) to William P. Hobby Airport (HOU) one to three months prior to your departure. Travelers who book domestic flights 34 to 86 days in advance can save 25% compared to those who book just 6 to 12 days ahead. Regardless of fare type and journey, the best day to book a domestic flight is usually Sunday and the most expensive day is typically Monday. Passengers who book on a Sunday can save 6% on average compared to those who book on a Monday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC’s global airline sales database.

Simply enter your dates, hit search and check the “Nonstop” filter on Expedia to browse any direct flights from MSP to HOU with American Airlines or other carriers.

Browse American Airlines’s earliest flights from MSP to HOU by using the “Early Morning” and “Morning” filters. Not only will you get to where you’re going sooner, early departures also have a 20% less chance of being canceled.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.

Take an American Airlines flight from Minneapolis - St. Paul Intl. Airport (MSP) to Houston, and you’re most likely to touch down at William P. Hobby Airport (HOU). This is the airline’s main hub here.

Depending on the type of fare you purchased, a fee is typically charged if you cancel or change your flight more than 24 hours after confirmation. To secure flexible fares, select our “Changes included” and “No cancel fee” boxes while looking for flights. For more details on modifying or canceling your reservation, go to “Trips,” select your flight and click on “Manage Booking.”