$130 Cheap American Airlines flights San Antonio (SAT) to Key West (EYW)

Finding cheap one-way American Airlines flights from SAT to EYW from $130 on Expedia is a cinch — just filter by “Price (lowest to highest).” Alternatively, check out our budget-friendly round-trip fares from $191 for your next exciting vacation.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

September is one of the least expensive months to fly to Key West with American Airlines. You could also find great deals on one-way and return fares in August.

To find cheap American Airlines fares from San Antonio Intl. Airport (SAT) to Key West Intl. Airport (EYW), start searching one to three months before your intended departure. Securing domestic flights 34 to 86 days in advance could save you 25% compared to booking just 6 to 12 days ahead. The day you book can also influence the cost. Sunday is typically the most affordable, while Monday is often the most expensive for domestic flights. You can save 6% on average by booking your trip on a Sunday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC’s global airline sales database.

Use the “Nonstop” filter when searching for direct American Airlines flights from SAT to EYW. It’s also an easy way to compare other airlines offering the same direct route.

Find American Airlines’s earliest flights from SAT to EYW by checking our “Morning” and “Early Morning” filters. Not only will you arrive at your destination sooner, early departures also have a 20% less chance of being canceled.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.

American Airlines flights from San Antonio Intl. Airport (SAT) to Key West land at Key West Intl. Airport (EYW). This is the main gateway to this city.

Changes are typically free within 24 hours of making a booking, but your airline may add a charge after that. For further information about altering your reservation, check out your “Trips,” select your flight and click on “Manage Booking.” If you’d like the flexibility to make changes without being charged, apply the “No cancel fee” or “Changes included” filter when organizing your next trip.