$172 Cheap American Airlines flights Tucson (TUS) to Jacksonville (JAX)

Finding cheap one-way American Airlines flights from TUS to JAX from $172 on Expedia couldn't be simpler --- just filter by "Price (lowest to highest)." Or check out our affordable round-trip fares from $343 for your next exciting adventure.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Look for affordable American Airlines flights from Tucson Intl. Airport (TUS) to Jacksonville Intl. Airport (JAX) one to three months before your departure day. Travelers who book domestic flights 34 to 86 days in advance can save 25% compared to those who book just 6 to 12 days ahead. No matter the fare type and journey, the best day to book a domestic flight is generally Sunday and the most expensive is typically Monday. Passengers who book on a Sunday can save 6% on average compared to those who book their travel on a Monday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

To find the earliest departure from TUS to JAX with American Airlines, filter your search by "Early Morning" and "Morning." Choosing an early flight usually means cancellations are less likely.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.