$142 Cheap Delta flights Key West (EYW) to Detroit (DTW)

Grab affordable round-trip Delta Air Lines flights from $306 from EYW to DTW by organizing your results from "Price (lowest to highest)" on Expedia. Or search for options from $142 for a one-way journey.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Start searching one to three months before your departure to find cheap fares on Delta Air Lines flights from Key West Intl. Airport (EYW) to Detroit Metropolitan Wayne County Airport (DTW). You can save 25% by booking your domestic flight 34 to 86 days in advance compared to last-minute reservations made 6 to 12 days out. You could also cut costs by buying your fare on a Sunday, as it's 6% cheaper on average than a Monday, the most expensive day to book.* Get your timing spot on, and you can enjoy significant savings on domestic trips.*Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

Filter your results by "Early Morning" and "Morning" to see the earliest flights from EYW to DTW. Jetting off early means you're 20% less likely to experience cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.

Delta Air Lines makes flying from EYW to DTW more comfortable with a rewarding loyalty program and an excellent in-flight experience. You could even start collecting points with Delta SkyMiles. Be sure to sign up to Expedia's free One Key™ rewards program to earn OneKeyCash™*, which can be redeemed on future trips.*OneKeyCash™ disclaimer - OneKeyCash™ is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.