$169 Cheap Delta flights St. Louis (STL) to Roanoke (ROA)

View $169 flight on Wed, Aug 27, 2025Opens in a new window

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$169 Cheap Delta flights St. Louis (STL) to Roanoke (ROA)

Prices were available within the past 7 days and start at $169 for one-way flights and $249 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Thu, Aug 28 - Sun, Aug 31
STL
St. Louis
ROA
Roanoke
$249 Roundtrip, just found
$249
Roundtrip
just found
Select Delta flight, departing Thu, Aug 28 from St. Louis to Roanoke, returning Sun, Aug 31, priced at $249 just found
Delta
Thu, Jul 17 - Tue, Jul 22
STL
St. Louis
ROA
Roanoke
$259 Roundtrip, found 17 hours ago
$259
Roundtrip
found 17 hours ago
Select Delta flight, departing Thu, Jul 17 from St. Louis to Roanoke, returning Tue, Jul 22, priced at $259 found 17 hours ago
Delta
Sun, Oct 12 - Tue, Oct 21
STL
St. Louis
ROA
Roanoke
$279 Roundtrip, found 1 hour ago
$279
Roundtrip
found 1 hour ago
Select Delta flight, departing Sun, Oct 12 from St. Louis to Roanoke, returning Tue, Oct 21, priced at $279 found 1 hour ago
Delta
Fri, Jul 18 - Tue, Jul 22
STL
St. Louis
ROA
Roanoke
$284 Roundtrip, found 17 hours ago
$284
Roundtrip
found 17 hours ago
Select Delta flight, departing Fri, Jul 18 from St. Louis to Roanoke, returning Tue, Jul 22, priced at $284 found 17 hours ago
Delta
Wed, Nov 19 - Wed, Nov 26
STL
St. Louis
ROA
Roanoke
$297 Roundtrip, found 2 days ago
$297
Roundtrip
found 2 days ago
Select Delta flight, departing Wed, Nov 19 from St. Louis to Roanoke, returning Wed, Nov 26, priced at $297 found 2 days ago
Delta
Tue, Oct 7 - Fri, Oct 10
STL
St. Louis
ROA
Roanoke
$304 Roundtrip, found 1 hour ago
$304
Roundtrip
found 1 hour ago
Select Delta flight, departing Tue, Oct 7 from St. Louis to Roanoke, returning Fri, Oct 10, priced at $304 found 1 hour ago
Flights from St. Louis (STL) to Roanoke (ROA)
Origin airport
Lambert-St. Louis Intl.
Destination airport
Roanoke Regional
Airlines serving
American Airlines, Delta, United
Popular airline
American Airlines
Distance
573 mi

Frequently asked questions

How much is a Delta Air Lines flight from Lambert-St. Louis Intl. Airport (STL) to Roanoke Regional Airport (ROA)?
Landing cheap one-way Delta Air Lines flights from STL to ROA from $169 on Expedia is a cinch --- just filter by "Price (lowest to highest)." Or check out our affordable return fares from $249 for your next adventure.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.
What is the cheapest month to fly from STL to ROA with Delta Air Lines?
Search for one-way or round-trip flights to Roanoke in January or February. You could find an affordable fare with Delta Air Lines during these off-peak travel months.
What is the cheapest time to book flights from Lambert-St. Louis Intl. Airport (STL) to Roanoke Regional Airport (ROA) with Delta Air Lines?
Search for cheap Delta Air Lines flights from Lambert-St. Louis Intl. Airport (STL) to Roanoke Regional Airport (ROA) one to three months prior to your day of departure. Travelers who book domestic flights 34 to 86 days in advance can save 25% compared to those who book just 6 to 12 days ahead. No matter the fare class and journey, the ideal day to book a domestic flight is usually Sunday and the most expensive is typically Monday. Passengers who book on a Sunday can save 6% on average compared to those who book their travel on a Monday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.
Does Delta Air Lines fly nonstop from Lambert-St. Louis Intl. Airport (STL) to Roanoke Regional Airport (ROA)?
Use our "Nonstop" filter when browsing for direct Delta Air Lines flights from STL to ROA. It's also an easy way to compare other carriers offering the same nonstop trip.
What is the earliest Delta Air Lines flight from STL to ROA?
To find the earliest departures from STL to ROA with Delta Air Lines, filter your results by "Early Morning" and "Morning." Booking an early flight usually means you'll experience fewer cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports does Delta Air Lines fly into in Roanoke?
Hop on a Delta Air Lines flight from Lambert-St. Louis Intl. Airport (STL) to Roanoke, and you're most likely to touch down at Roanoke Regional Airport (ROA). This is the airline's primary hub here.
Why fly with Delta Air Lines from STL to ROA?
Traveling from STL to ROA with Delta Air Lines means enjoying plenty of perks, such as an excellent in-flight experience and a rewarding loyalty program. Plus, when booking through Expedia, One Key™ members can collect OneKeyCash™* to redeem on select future travel purchases. That's in addition to the Delta SkyMiles points you can earn with Delta Air Lines.*OneKeyCash™ disclaimer - OneKeyCash™ is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
Can I change or cancel my Delta Air Lines flight from Lambert-St. Louis Intl. Airport (STL) to Roanoke Regional Airport (ROA)?
You can usually cancel or reschedule your flight, although additional charges may apply if you booked over 24 hours ago. Need flexible options? Make use of Expedia's "Changes included" and "No cancel fee" filters to find flights that won't charge extra if you have to revise your plans. To make modifications, visit "Trips," select your flight and click on "Manage Booking" for more information.

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