$131 Cheap flights from Hartsville, SC

View $131 flight on Tue, Dec 8, 2026

Popular airlines from Hartsville

  • Be in the know

    Get alerts if flight prices drop or rise*

  • Book smarter

    Save up to 30% on select hotels after you book a flight*

  • Earn twice

    Earn your airline miles on top of our OneKeyCash

    Learn about One Key

  • Cheapest flights from Hartsville

    Prices were available within the past 7 days and start at $131 for one-way flights and $261 for roundtrip, for the period specified. Prices and availability are subject to change.

    All deals

    One way

    Roundtrip

    Select American Airlines flight, departing Wed, Jan 13 from Florence to Memphis, returning Tue, Jan 19, priced at $261 Found 1 day ago

    Wed, Jan 13 - Tue, Jan 19 · FLO · MEM · Roundtrip

    Select American Airlines flight, departing Sat, Dec 12 from Florence to Boston, returning Tue, Dec 15, priced at $261 Found 1 day ago

    Sat, Dec 12 - Tue, Dec 15 · FLO · BOS · Roundtrip

    Select American Airlines flight, departing Tue, Jan 5 from Florence to Fort Lauderdale, returning Sat, Jan 16, priced at $289 Found 3 days ago

    Tue, Jan 5 - Sat, Jan 16 · FLO · FLL · Roundtrip

    Select American Airlines flight, departing Fri, Jan 22 from Florence to New York, returning Tue, Feb 2, priced at $311 Found 1 day ago

    Fri, Jan 22 - Tue, Feb 2 · FLO · JFK · Roundtrip

    Select American Airlines flight, departing Sat, Feb 27 from Florence to New York, returning Wed, Mar 3, priced at $316 Found 4 days ago

    Sat, Feb 27 - Wed, Mar 3 · FLO · JFK · Roundtrip

    Select American Airlines flight, departing Fri, Jan 22 from Florence to New York, returning Mon, Feb 1, priced at $361 Found 5 hours ago

    Fri, Jan 22 - Mon, Feb 1 · FLO · JFK · Roundtrip

    Select American Airlines flight, departing Tue, Dec 8 from Florence to Memphis, returning Tue, Dec 15, priced at $367 Found 1 day ago

    Tue, Dec 8 - Tue, Dec 15 · FLO · MEM · Roundtrip

    Select American Airlines flight, departing Sat, Dec 12 from Florence to New York, returning Tue, Dec 15, priced at $371 Found 1 day ago

    Sat, Dec 12 - Tue, Dec 15 · FLO · LGA · Roundtrip

    Select American Airlines flight, departing Mon, Feb 15 from Florence to Boston, returning Wed, Feb 24, priced at $375 Found 18 hours ago

    Mon, Feb 15 - Wed, Feb 24 · FLO · BOS · Roundtrip

    Select American Airlines flight, departing Sat, Dec 12 from Florence to Boston, returning Tue, Dec 15, priced at $376 Found 5 days ago

    Sat, Dec 12 - Tue, Dec 15 · FLO · BOS · Roundtrip

    How to Find Cheap Flights from Hartsville, SC

    How much is a flight from Hartsville?

    This week, flights from Hartsville are available between $261 – $376.

    How to find cheap flights from Hartsville?

    Expedia makes it easy to compare cheap flights from Hartsville to many destinations. Check out excellent deals on domestic and international flights from Hartsville. Once you select an offer, use our filters and sort by “Price (Lowest)” to see some of the cheapest and suitable options.

    How can I get the best deal on flights from Hartsville?

    On Expedia, you have some of best airline ticket deals at your fingertips. Whether it’s a beach escape with your partner, a family vacation with your kids, or business trip with colleagues, these low airline ticket prices mean more savings for you. An excellent strategy for finding some of the best deals on flights from Hartsville is to be flexible with your dates. Within each offer, you can compare prices for similar timeframes using our “Show flexible dates” feature. Depending on your destination, direct flights from Hartsville may be more expensive. Airlines with strict bag policies or fees can also impact your costs.

    What is the best airline to fly from Hartsville?

    At Expedia, we give you all the available options from our reputable partners. Select the airline that best suits your preferences and membership loyalties. You can fly from Hartsville with: American Airlines.

    What is the best month to fly from Hartsville?

    One of the cheapest times to fly from Hartsville airport(s) is January, based on the current list of flights available now. Prices on plane tickets vary considerably throughout the year due to availability and seasonal demand.

    Are there any last-minute flights from Hartsville?

    Expedia is the place to find last-minute flights from Hartsville, making it easy for you to compare prices on flights in the near future for different combinations of travel dates and from multiple airlines. We source some of the best deals for you and display some of the best offers available over the next 2 weeks.

    Why book your ticket with Expedia?

    Booking flights from Hartsville with Expedia is the obvious choice to get low prices, save money, and see more value from every dollar spent. We show you some of the best deals happening right now and provide a vast inventory of airlines and flight routes to choose from, so you can find some of the cheapest flights from Hartsville. You can customize your journey to your timeline, route preferences, budget, rewards programs, and more.

    Can I change/cancel my flight?

    Some flights can be changed or canceled, but fees and refunds will depend on the unique terms of your flight agreement. Airlines have different rules and restrictions for exchanging or refunding flights. For more information, go to your itinerary or visit our customer service portal. We recommend choosing flights with no change fees for the most flexibility. Filter by “Flexible change policies” to see flights with no change fees.

    Travel information

    Origin city nameFlorence
    Origin airportFlorence, SC
    Origin airport IATA codeFLO
    Airlines servingAmerican Airlines
    Popular airlineAmerican Airlines
    Roundtrip price$261

    Explore a world of travel with Expedia

    *Available to One Key members.