A panoramic view of a historic city with a river, prominent domed buildings, and a bridge.

Florence Vacation Rentals

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Check prices for these dates

In two weeks
Jul 10 - Jul 12
In two months
Aug 21 - Aug 23
In three months
Sep 18 - Sep 20
In four months
Oct 16 - Oct 18

Our top choices for Florence vacation rentals

Microwave, oven, stovetop, dishwasher

Charming 2-bedroom apartment MINUTES from Darlington Raceway with pond views

Charming 2-bedroom apartment MINUTES from Darlington Raceway with pond views
Hartsville
10.0 out of 10, Exceptional, (12 reviews)
"Very clean, stayed here for work. Would definitely book again if in the area. "
United States
Kacey
$150 nightly
The price is $164
Jul 7 - Jul 8
Total with taxes and fees
Charming 2-bedroom apartment MINUTES from Darlington Raceway with pond views
1 bedroom, iron/ironing board, travel crib, free WiFi

Charming Cottage with easy access to local attractions-pet and kid friendly

Charming Cottage with easy access to local attractions-pet and kid friendly
Sellers
9.6 out of 10, Exceptional, (28 reviews)
"A great place to stay with our two dogs. We will be back again soon."
United States
Marianne P.
$181 nightly
The price is $197
Jun 30 - Jul 1
Total with taxes and fees
Charming Cottage with easy access to local attractions-pet and kid friendly
1 bedroom, free WiFi, bed sheets

imperial motel

imperial motel
Mullins
$97 nightly
The price is $106
Jun 29 - Jun 30
Total with taxes and fees
imperial motel
Exterior

In 1840 Burn Cottage

In 1840 Burn Cottage
Society Hill
9.6 out of 10, Exceptional, (35 reviews)
"Nice historic house provided authentic late-1800s three night stay. Enjoyed our stay."
United States
Ansel C.
$188 nightly
The price is $205
Jul 1 - Jul 2
Total with taxes and fees
In 1840 Burn Cottage
Smart TV, books

Peaceful Farm Getaway

Peaceful Farm Getaway
Mullins
10.0 out of 10, Exceptional, (36 reviews)
"Awesome location near family for the holiday. I can’t wait to book again "
United States
sheliars1 ..
$195 nightly
The price is $213
Jun 28 - Jun 29
Total with taxes and fees
Peaceful Farm Getaway
2 bedrooms, WiFi, bed sheets

Lakeside 2-bedroom RV in charming Hartsville with AC, WiFi

Lakeside 2-bedroom RV in charming Hartsville with AC, WiFi
Hartsville
8.0 out of 10, Very Good, (1 review)
"The stay was fine , with no problems."
United States
Mark H.
$138 nightly
The price is $150
Jun 28 - Jun 29
Total with taxes and fees
Lakeside 2-bedroom RV in charming Hartsville with AC, WiFi
Interior

Walking distance from one of South Carolina's top Medical centers.

Walking distance from one of South Carolina's top Medical centers.
Florence
9.8 out of 10, Exceptional, (53 reviews)
"Our third time staying at this home and always have had a great experience. Such a comfy home and very well stocked. Great hosts!"
United States
Kelly W.
Walking distance from one of South Carolina's top Medical centers.
Dining

Beautiful 1-bedroom apartment perfect for traveling professionals.

Beautiful 1-bedroom apartment perfect for traveling professionals.
Bishopville
$124 nightly
The price is $138
Jul 3 - Jul 4
Total with taxes and fees
Beautiful 1-bedroom apartment perfect for traveling professionals.
Fridge, microwave, oven, stovetop

The Pinecone Retreat - Only 1 mile from i95

The Pinecone Retreat - Only 1 mile from i95
Latta
10.0 out of 10, Exceptional, (2 reviews)
"So comfy and cozy but plenty of room for our family of four!"
United States
Nita S.
$140 nightly
The price is $153
Jun 28 - Jun 29
Total with taxes and fees
The Pinecone Retreat - Only 1 mile from i95
Dining

Charming 3-bedroom, 2.5 bath townhome. Largest with accommodations in Florence.

Charming 3-bedroom, 2.5 bath townhome. Largest with accommodations in Florence.
Florence
8.6 out of 10, Excellent, (4 reviews)
"Convenient location"
United States
Bonney W.
$451 nightly
The price is $505
Jun 28 - Jun 29
Total with taxes and fees
Charming 3-bedroom, 2.5 bath townhome. Largest with accommodations in Florence.
Interior

Secret SC Cabin on 100 acres Hot Tub Large Pond

Secret SC Cabin on 100 acres Hot Tub Large Pond
Marion
9.6 out of 10, Exceptional, (184 reviews)
"Great location and house and the host was excellent!"
United States
Josh R.
$432 nightly
The price is $470
Jun 28 - Jun 29
Total with taxes and fees
Secret SC Cabin on 100 acres Hot Tub Large Pond
Interior

Wonderful 2-bedroom house charming ranch style home

Wonderful 2-bedroom house charming ranch style home
Florence
$151 nightly
The price is $169
Jul 1 - Jul 2
Total with taxes and fees
Wonderful 2-bedroom house charming ranch style home
Dining

Located in Marion. Only 1 hour from Myrtle Beach, 35 minutes from Florence!

Located in Marion. Only 1 hour from Myrtle Beach, 35 minutes from Florence!
Marion
9.0 out of 10, Wonderful, (6 reviews)
"It was a great place. "
United States
Cindy N.
$547 nightly
The price is $596
Jun 27 - Jun 28
Total with taxes and fees
Located in Marion. Only 1 hour from Myrtle Beach, 35 minutes from Florence!
Interior

Take a rest in Florence .Ideal for i95 traveler and Florence Center and Buc-ee's

Take a rest in Florence .Ideal for i95 traveler and Florence Center and Buc-ee's
Florence
10.0 out of 10, Exceptional, (56 reviews)
"Great place, always clean and a top notch stay!"
United States
K H.
$249 nightly
The price is $279
Jul 12 - Jul 13
Total with taxes and fees
Take a rest in Florence .Ideal for i95 traveler and Florence Center and Buc-ee's
Interior

Perfect Stop • Near I-95, Downtown & Civic Center and Darlington

Perfect Stop • Near I-95, Downtown & Civic Center and Darlington
Florence
10.0 out of 10, Exceptional, (11 reviews)
$255 nightly
The price is $286
Jun 29 - Jun 30
Total with taxes and fees
Perfect Stop • Near I-95, Downtown & Civic Center and Darlington
Property grounds

The Perfect Home Base to Explore The Carolinas, See Family, or Find Quiet

The Perfect Home Base to Explore The Carolinas, See Family, or Find Quiet
Bennettsville
9.8 out of 10, Exceptional, (30 reviews)
"Far from the Madding Crowd, this farm property is hidden in a field surrounded by trees. Very quiet."
United States
Anand
$71 nightly
The price is $79
Jun 29 - Jun 30
Total with taxes and fees
The Perfect Home Base to Explore The Carolinas, See Family, or Find Quiet
Fridge, microwave, oven, stovetop

Camden Cottage

Camden Cottage
Camden
10.0 out of 10, Exceptional, (64 reviews)
"The location really is the highlight and the bed is excellent. "
United States
Paul C.
$159 nightly
The price is $178
Jul 6 - Jul 7
Total with taxes and fees
Camden Cottage
Smart TV, books

Charming 2-bedroom house with AC, WiFi in the heart of Pembroke

Charming 2-bedroom house with AC, WiFi in the heart of Pembroke
Pembroke
9.8 out of 10, Exceptional, (6 reviews)
"Great location and so much better then staying in a hotel!"
United States
Teresa G.
$326 nightly
The price is $368
Jun 27 - Jun 28
Total with taxes and fees
Charming 2-bedroom house with AC, WiFi in the heart of Pembroke
Interior

Queen Bed Non-Smoking

Queen Bed Non-Smoking
Chesterfield, SC
$110 nightly
The price is $122
Jun 27 - Jun 28
Total with taxes and fees
Queen Bed Non-Smoking
Property grounds

Cozy 1-bedroom apartment at Greenleaf Villa. Downtown Camden, SC.

Cozy 1-bedroom apartment at Greenleaf Villa. Downtown Camden, SC.
Camden
10.0 out of 10, Exceptional, (11 reviews)
$134 nightly
The price is $150
Jul 5 - Jul 6
Total with taxes and fees
Cozy 1-bedroom apartment at Greenleaf Villa. Downtown Camden, SC.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Florence Hotel Reviews

La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence

8/10 Good
"It was okay. Pet area improved since last visit."
Gary 1-night trip
Posted less than an hour ago
La Quinta Inn & Suites by Wyndham Florence

Find out more about Florence

Everything you need to know about Florence vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Florence vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Florence vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Florence vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Florence. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Florence in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $79 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Florence rentals

At Expedia, we put the best Florence vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Florence rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Florence vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Florence. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Explore a world of travel with Expedia

Frequently asked questions

Can I find vacation rentals in Florence?

Yes, we have vacation rentals in Florence close to Eastern Carolina Agricultural Fairgrounds, or you can choose a secluded option if you'd like a relaxing place to stay. Tourists like the array of shops and top-notch restaurants in Florence. You can also check out the entertainment venues while you're visiting.

What are some of the best vacation rentals in Florence?

Charming 3-bedroom, 2.5 bath townhome. Largest with accommodations in Florence.: Visitors give good reviews to this Florence vacation home rental, which has air-conditioning and laundry facilities to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a dishwasher, a fridge, and a stovetop. Our travelers also rate Walking distance from one of South Carolina's top Medical centers. as a favorite home for rent in Florence.

How many vacation rentals will I find in Florence?

Choose from 37 Expedia vacation rentals in Florence for a memorable vacation.

What can I see and do in Florence?

Palmetto Shores Lake and Florence Veterans Park are a couple of scenic spots to enjoy the outdoors, whereas Florence Museum is one of the cultural attractions. Other places in town to visit include Magnolia Mall and Florence Civic Center.

What are vacation rentals like in Florence?

Vacation rentals are privately owned accommodations you can reserve for a couple days or more in Florence. Vacation rentals offer extras such as hot tubs, fire pits, and patios so you'll have a home away from home. If you're concerned about cleanliness, a vacation rental can provide a sense of privacy away from public hotel elevators and busy concierge desks while still allowing you to travel. You'll also get more space in a vacation rental than in a traditional hotel, which is another reason why a vacation rental is a popular choice for a family trip or a small group gathering.