
Popular airlines from Palo Alto to San Diego
- Alaska Airlines
Alaska Airlines
- American Airlines
American Airlines
- Frontier Airlines
Frontier Airlines
- Spirit Airlines
Spirit Airlines
- Delta
Delta
- Southwest Airlines
Southwest Airlines
- United
United
- Plan, book, fly with confidence
trending down icon Be in the knowGet alerts if flight prices drop or rise*bex rewards loyalty icon Book smarterSave up to 30% on select hotels after you book a flight*one key icon
Today's featured flight deals from Palo Alto to San Diego
Nonstop
Carry-on included
Lower price than typical
- San Jose (SJC) to San Diego (SAN).Southwest Airlines, nonstop.Departing on Thu, Aug 28 at 6:30am from San Jose, arriving at 8:00am in San Diego.Returning on Mon, Sep 1 at 6:20am from San Diego, arriving at 10:11am in San Jose.Select Southwest Airlines flight departing on Thu, Aug 28 at 6:30am from San Jose, returning on Mon, Sep 1 at 6:20am from San Diego priced at $18860% less than typical$188
- San Jose (SJC) to San Diego (SAN).Alaska Airlines, nonstop.Departing on Fri, Aug 8 at 6:15am from San Jose, arriving at 7:55am in San Diego.Returning on Sun, Aug 17 at 6:20am from San Diego, arriving at 10:34am in San Jose.Select Alaska Airlines flight departing on Fri, Aug 8 at 6:15am from San Jose, returning on Sun, Aug 17 at 6:20am from San Diego priced at $31045% less than typical$310
- San Jose (SJC) to San Diego (SAN).Alaska Airlines, nonstop.Departing on Fri, Aug 8 at 3:17pm from San Jose, arriving at 4:52pm in San Diego.Returning on Sun, Aug 17 at 6:20am from San Diego, arriving at 10:34am in San Jose.Select Alaska Airlines flight departing on Fri, Aug 8 at 3:17pm from San Jose, returning on Sun, Aug 17 at 6:20am from San Diego priced at $31045% less than typical$310
- San Jose (SJC) to San Diego (SAN).Southwest Airlines, nonstop.Departing on Wed, Aug 13 at 8:30pm from San Jose, arriving at 9:50pm in San Diego.Returning on Sun, Aug 17 at 6:20am from San Diego, arriving at 10:34am in San Jose.Select Southwest Airlines flight departing on Wed, Aug 13 at 8:30pm from San Jose, returning on Sun, Aug 17 at 6:20am from San Diego priced at $30540% less than typical$305
- San Francisco (SFO) to San Diego (SAN).Frontier Airlines, nonstop.Departing on Mon, Aug 4 at 10:37am from San Francisco, arriving at 12:17pm in San Diego.Returning on Fri, Aug 8 at 7:35pm from San Diego, arriving at 11:11pm in San Francisco.Select Frontier Airlines flight departing on Mon, Aug 4 at 10:37am from San Francisco, returning on Fri, Aug 8 at 7:35pm from San Diego priced at $17455% less than typical$174
- San Francisco (SFO) to San Diego (SAN).Frontier Airlines, nonstop.Departing on Mon, Aug 4 at 10:37am from San Francisco, arriving at 12:17pm in San Diego.Returning on Sat, Aug 9 at 12:50pm from San Diego, arriving at 8:01pm in San Francisco.Select Frontier Airlines flight departing on Mon, Aug 4 at 10:37am from San Francisco, returning on Sat, Aug 9 at 12:50pm from San Diego priced at $17355% less than typical$173
- San Francisco (SFO) to San Diego (SAN).Alaska Airlines, nonstop.Departing on Sun, Aug 10 at 7:20am from San Francisco, arriving at 9:02am in San Diego.Returning on Sun, Aug 17 at 6:30am from San Diego, arriving at 8:10am in San Francisco.Select Alaska Airlines flight departing on Sun, Aug 10 at 7:20am from San Francisco, returning on Sun, Aug 17 at 6:30am from San Diego priced at $19350% less than typical$193
- San Francisco (SFO) to San Diego (SAN).Alaska Airlines, nonstop.Departing on Sun, Aug 10 at 7:20am from San Francisco, arriving at 9:02am in San Diego.Returning on Mon, Aug 18 at 5:53pm from San Diego, arriving at 7:39pm in San Francisco.Select Alaska Airlines flight departing on Sun, Aug 10 at 7:20am from San Francisco, returning on Mon, Aug 18 at 5:53pm from San Diego priced at $16855% less than typical$168
- San Francisco (SFO) to San Diego (SAN).Alaska Airlines, nonstop.Departing on Sun, Aug 10 at 6:00am from San Francisco, arriving at 7:42am in San Diego.Returning on Mon, Aug 18 at 5:53pm from San Diego, arriving at 7:39pm in San Francisco.Select Alaska Airlines flight departing on Sun, Aug 10 at 6:00am from San Francisco, returning on Mon, Aug 18 at 5:53pm from San Diego priced at $16855% less than typical$168
Cheap Flights from Palo Alto to San Diego (SJC-SAN)
Prices were available within the past 7 days and start at $29 for one-way flights and $58 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Aug 23 - Mon, Aug 25
OAK
Oakland
SAN
San Diego
$58 Roundtrip, just found
$58
Roundtrip
just found

Fri, Sep 12 - Mon, Sep 15
OAK
Oakland
SAN
San Diego
$65 Roundtrip, just found
$65
Roundtrip
just found

Sat, Aug 9 - Thu, Aug 21
SFO
San Francisco
SAN
San Diego
$87 Roundtrip, found 3 hours ago
$87
Roundtrip
found 3 hours ago

Tue, Sep 16 - Fri, Sep 19
OAK
Oakland
SAN
San Diego
$93 Roundtrip, found 12 hours ago
$93
Roundtrip
found 12 hours ago

Wed, Sep 17 - Sat, Sep 20
SFO
San Francisco
SAN
San Diego
$97 Roundtrip, just found
$97
Roundtrip
just found

Tue, Aug 26 - Sat, Sep 6
SJC
San Jose
SAN
San Diego
$97 Roundtrip, found 17 hours ago
$97
Roundtrip
found 17 hours ago
Find the cheapest month to fly from San Francisco (SFO) to San Diego (SAN)
September is typically the cheapest month to fly
From $48 - $87 per traveler.
Graph displaying average flight prices per month
Alternative airports near San Diego
Prices were available within the past 7 days. Prices and availability are subject to change.
Explore a world of travel with Expedia
- San Diego County Hotels
- Cheap Hotels in San Diego County
- Hotels near Downtown San Diego
- Beach Hotels in San Diego County
- Hotels near Gaslamp Quarter
- Oceanfront Hotels in San Diego County
- Hotels near San Diego Convention Center
- Pet-friendly Hotels in San Diego County
- Hotels near Petco Park
- Family Hotels in San Diego County
- Casino Hotels in San Diego County
- Motels in San Diego County
- All-inclusive Resorts in San Diego County
- Hotels with Waterslides in San Diego County
- Cabin Rentals in San Diego County
- Resorts & Hotels with Spas in San Diego County
- RV Parks in San Diego County
- Hotels with a Lazy River in San Diego County
- Hotels near San Diego Zoo
- Golf Hotels in San Diego County
- Houseboats in San Diego County
- Cheap Hotels in Downtown San Diego
- Resorts in San Diego County
- Honeymoon Resorts & in San Diego County
- Hotels with an Indoor Pool in San Diego County
- Historic Hotels in San Diego County
- Luxury Hotels in San Diego County
- Hotels with a Swim-up Bar in San Diego County
- Hotels with Free Airport Shuttle in San Diego County
- Hotels with a Pool in San Diego County
- Aparthotels in San Diego County
- Hotels with Early Check-in in San Diego County
- Hotels with smoking rooms in San Diego County
- Hotels on the Lake in San Diego County
- Waterpark Hotels in San Diego County
- Hotels near San Diego Intl.
- Winery Hotels in San Diego County
- Condo Resorts in San Diego County
- Hotels with Kitchenettes in San Diego County
- Romantic Hotels in San Diego County
- Business Hotels in San Diego County
- Boutique Hotels in San Diego County
- Adults Only Resorts & in San Diego County
- Hotels with Suites in San Diego County
- B&B in San Diego County
- Ski Hotels in San Diego County
- Farmstay in San Diego County
- Condo Rentals in San Diego County
- Hotels with Childcare in San Diego County
- Ranches in San Diego County
- Hotels with Connecting Rooms in San Diego County
- Hotels with Fireplaces in San Diego County
- Apartments in San Diego County
- Cottages in San Diego County
- Hotels with Room Service in San Diego County
- Villas in San Diego County
- Hotel Wedding Venues Hotels in San Diego County
- Hostels in San Diego County
- Flights from San Francisco (SFO) to San Diego (SAN)
- Flights from Seattle (SEA) to San Diego (SAN)
- Flights from Phoenix (PHX) to San Diego (SAN)
- Flights from New York (JFK) to San Diego (SAN)
- Flights from Las Vegas (LAS) to San Diego (SAN)
- Flights from Chicago (ORD) to San Diego (SAN)
- Flights from Dallas (DFW) to San Diego (SAN)
- Flights from San Jose (SJC) to San Diego (SAN)
- Flights from Los Angeles (LAX) to San Diego (SAN)
- Flights from Denver (DEN) to San Diego (SAN)
- Flights from Portland (PDX) to San Diego (SAN)
- Flights from Boston (BOS) to San Diego (SAN)
- Flights from Sacramento (SMF) to San Diego (SAN)
- Flights from Houston (IAH) to San Diego (SAN)
- Flights from Salt Lake City (SLC) to San Diego (SAN)
- Flights from Fresno (FAT) to San Diego (SAN)
- Flights from Minneapolis (MSP) to San Diego (SAN)
- Flights from Atlanta (ATL) to San Diego (SAN)
- Flights from Philadelphia (PHL) to San Diego (SAN)
- Flights from Detroit (DTW) to San Diego (SAN)
- Flights to San Diego County
- Flights from Washington (IAD) to San Diego (SAN)
- Flights from San Diego Intl.
- Flights from Orlando (MCO) to San Diego (SAN)
- Flights from Honolulu (HNL) to San Diego (SAN)
- Flights from Oakland (OAK) to San Diego (SAN)
- Flights from Austin (AUS) to San Diego (SAN)
- Flights from Charlotte (CLT) to San Diego (SAN)
- Flights from San Diego County
- Car rental San Diego Airport (SAN)
- Car rentals near San Diego County
- Car rentals near Downtown San Diego
- Convertible Car Rentals in San Diego County
- Van Car Rentals in San Diego County
- Fullsize Car Rentals in San Diego County
- Europcar Rental Cars in San Diego County
- Minivan Car Rentals in San Diego County
*Available to One Key members.