$375 Cheap Flights from Buffalo (BUF) to Brussels (BRU)

View $375 flight on Tue, Feb 3, 2026Opens in a new window

Popular airlines from Buffalo Niagara Intl. Airport (BUF) to Brussels Airport (BRU)

Cheap Flights from Buffalo to Brussels (BUF-BRU)

Prices were available within the past 7 days and start at $375 for one-way flights and $457 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Sun, Mar 8 - Tue, Mar 24
BUF
Buffalo
BRU
Brussels
$457 Roundtrip, found 23 hours ago
$457
Roundtrip
found 23 hours ago
Select Delta flight, departing Sun, Mar 8 from Buffalo to Brussels, returning Tue, Mar 24, priced at $457 found 23 hours ago
American Airlines
Tue, Feb 3 - Tue, Feb 17
BUF
Buffalo
BRU
Brussels
$472 Roundtrip, found 7 hours ago
$472
Roundtrip
found 7 hours ago
Select American Airlines flight, departing Tue, Feb 3 from Buffalo to Brussels, returning Tue, Feb 17, priced at $472 found 7 hours ago
British Airways
Tue, Feb 3 - Tue, Feb 10
BUF
Buffalo
BRU
Brussels
$473 Roundtrip, found 4 days ago
$473
Roundtrip
found 4 days ago
Select British Airways flight, departing Tue, Feb 3 from Buffalo to Brussels, returning Tue, Feb 10, priced at $473 found 4 days ago
Iberia
Tue, Jan 13 - Tue, Jan 20
BUF
Buffalo
BRU
Brussels
$488 Roundtrip, found 4 days ago
$488
Roundtrip
found 4 days ago
Select Iberia flight, departing Tue, Jan 13 from Buffalo to Brussels, returning Tue, Jan 20, priced at $488 found 4 days ago
Delta
Thu, Feb 26 - Tue, Mar 17
BUF
Buffalo
BRU
Brussels
$492 Roundtrip, found 23 hours ago
$492
Roundtrip
found 23 hours ago
Select Delta flight, departing Thu, Feb 26 from Buffalo to Brussels, returning Tue, Mar 17, priced at $492 found 23 hours ago
British Airways
Fri, Jan 16 - Fri, Jan 23
BUF
Buffalo
BRU
Brussels
$499 Roundtrip, found 1 day ago
$499
Roundtrip
found 1 day ago
Select British Airways flight, departing Fri, Jan 16 from Buffalo to Brussels, returning Fri, Jan 23, priced at $499 found 1 day ago
Delta
Sun, Mar 8 - Mon, Mar 23
BUF
Buffalo
BRU
Brussels
$507 Roundtrip, found 23 hours ago
$507
Roundtrip
found 23 hours ago
Select Delta flight, departing Sun, Mar 8 from Buffalo to Brussels, returning Mon, Mar 23, priced at $507 found 23 hours ago
Delta
Thu, Mar 12 - Tue, Mar 24
BUF
Buffalo
BRU
Brussels
$513 Roundtrip, found 23 hours ago
$513
Roundtrip
found 23 hours ago
Select Delta flight, departing Thu, Mar 12 from Buffalo to Brussels, returning Tue, Mar 24, priced at $513 found 23 hours ago
Brussels Airlines
Wed, Jan 14 - Wed, Jan 21
BUF
Buffalo
BRU
Brussels
$606 Roundtrip, found 2 days ago
$606
Roundtrip
found 2 days ago
Select Brussels Airlines flight, departing Wed, Jan 14 from Buffalo to Brussels, returning Wed, Jan 21, priced at $606 found 2 days ago
Lufthansa
Wed, Jan 14 - Wed, Jan 21
BUF
Buffalo
BRU
Brussels
$606 Roundtrip, found 2 days ago
$606
Roundtrip
found 2 days ago
Select Lufthansa flight, departing Wed, Jan 14 from Buffalo to Brussels, returning Wed, Jan 21, priced at $606 found 2 days ago

Alternative airports near Brussels

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Brussels - National BRU. Cheapest and Closest option available. Average driving time to city center is 15 minutes. Flights from $1,563
BRU
Brussels - National
CheapestClosest
Average driving time to city center15 min
Flights from $1,563
Flights from Buffalo (BUF) to Brussels (BRU)
Origin airport
Buffalo Niagara Intl.
Destination airport
Brussels - National
Airlines serving
Aer Lingus, Air Canada, Air France, American Airlines, Austrian Airlines, British Airways, Brussels Airlines, Delta, Iberia, Icelandair, JetBlue Airways, KLM, LOT-Polish Airlines, Lufthansa, Scandinavian Airlines, TAP Portugal, Turkish Airlines, United
Roundtrip price
$457
Distance
3753 mi

Buffalo to Brussels Flights

The cheapest times to fly from Buffalo to Brussels

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Buffalo to Brussels are during the month of March. You can find some of the cheapest flights from Buffalo to Brussels with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Buffalo to Brussels

Sunday is one of the best days to book for cheap flights from Buffalo to Brussels: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Buffalo to Brussels

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Buffalo to Brussels in 2026. You can also book with separate airlines for your outbound and return journeys, from $375 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Buffalo to Brussels flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Buffalo to Brussels airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Buffalo Niagara Intl. Airport (BUF) to Brussels - National Airport (BRU) cost?
Get a cheap one-way flight from $375 or cheap return flight from $457 from Buffalo Niagara Intl. Airport (BUF) to Brussels - National Airport (BRU) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Buffalo Niagara Intl. Airport (BUF) to Brussels - National Airport (BRU)?
The cheapest month to fly from BUF to BRU is March, when there's less demand. Off-peak season is typically when you'll find cheap fares for travel between these airports.
What is the cheapest airline that flies from Buffalo Niagara Intl. Airport (BUF) to Brussels - National Airport (BRU)?
Expedia's filter tool lets you easily compare travel time, airlines and fares all in one place. Choose your preferences, then sort by "Price (lowest to highest)" to see which carrier offers the cheapest BUF to BRU flight.
How many flights per day from Buffalo Niagara Intl. Airport (BUF) to Brussels - National Airport (BRU)?
There aren't any daily direct flights available from Buffalo Niagara Intl. Airport (BUF) to Brussels - National Airport (BRU). But you can opt for flights with layovers. Filter your search results on Expedia to include one or more stops, and you'll be soaring above the clouds in no time at all.
What day of the week has the most flights from BUF to BRU?
Friday is generally the busiest day for flights, while Tuesday tends to be the quietest.* Keep in mind that flight schedules can vary depending on a number of factors, including the carrier and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Buffalo Niagara Intl. Airport (BUF) to Brussels - National Airport (BRU)?
To avoid potential delays on the Buffalo Niagara Intl. Airport (BUF) to Brussels - National Airport (BRU) route, travel before 3 PM. Departures after this time have a 22% higher chance of being canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Buffalo Niagara Intl. Airport (BUF) to Brussels - National Airport (BRU) last-minute?
Last-minute fares from BUF to BRU are typically more expensive. To lock in the best prices, start searching for flights well ahead of time. That being said, if your travel plans are flexible, you may land a cheap fare just before your departure.
Is it cheaper to book a BUF to BRU flight and hotel package?
Compared with arranging hotels and flights separately, booking a BUF to BRU flight and hotel package with Expedia could result in significant savings. Better yet, having everything in one easy place will take the hassle out of travel planning. Just secure your flights and choose from our wide range of stays, then tailor your trip with other add-ons like activities and car rentals.
Can I cancel or change the date of my flight from Buffalo Niagara Intl. Airport (BUF) to Brussels - National Airport (BRU)?
Typically, it's possible to reschedule or cancel your BUF to BRU flight. However, if the booking was made more than 24 hours ago, additional fees may apply. Check your airline's policies in your itinerary to see what changes are possible and whether any costs are involved. You'll also find more details on our Customer Service portal.

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*Available to One Key members.