$450 Cheap Flights from Columbia (CAE) to Brussels (BRU)

View $450 flight on Fri, Nov 28, 2025Opens in a new window

Popular airlines from Columbia Metropolitan Airport (CAE) to Brussels Airport (BRU)

Cheap Flights from Columbia to Brussels (CAE-BRU)

Prices were available within the past 7 days and start at $450 for one-way flights and $650 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Lufthansa
Fri, Nov 28 - Fri, Dec 5
CAE
Columbia
BRU
Brussels
$650 Roundtrip, just found
$650
Roundtrip
just found
Select Lufthansa flight, departing Fri, Nov 28 from Columbia to Brussels, returning Fri, Dec 5, priced at $650 just found
Lufthansa
Fri, Nov 28 - Fri, Dec 5
CAE
Columbia
BRU
Brussels
$663 Roundtrip, just found
$663
Roundtrip
just found
Select Lufthansa flight, departing Fri, Nov 28 from Columbia to Brussels, returning Fri, Dec 5, priced at $663 just found
Scandinavian Airlines
Sun, May 17 - Mon, May 25
CAE
Columbia
BRU
Brussels
$710 Roundtrip, found 4 days ago
$710
Roundtrip
found 4 days ago
Select Scandinavian Airlines flight, departing Sun, May 17 from Columbia to Brussels, returning Mon, May 25, priced at $710 found 4 days ago
Lufthansa
Fri, Nov 28 - Fri, Dec 5
CAE
Columbia
BRU
Brussels
$742 Roundtrip, just found
$742
Roundtrip
just found
Select Lufthansa flight, departing Fri, Nov 28 from Columbia to Brussels, returning Fri, Dec 5, priced at $742 just found
Lufthansa
Fri, Nov 28 - Fri, Dec 5
CAE
Columbia
BRU
Brussels
$755 Roundtrip, just found
$755
Roundtrip
just found
Select Lufthansa flight, departing Fri, Nov 28 from Columbia to Brussels, returning Fri, Dec 5, priced at $755 just found
Brussels Airlines
Fri, Nov 28 - Fri, Dec 5
CAE
Columbia
BRU
Brussels
$756 Roundtrip, just found
$756
Roundtrip
just found
Select Brussels Airlines flight, departing Fri, Nov 28 from Columbia to Brussels, returning Fri, Dec 5, priced at $756 just found
Scandinavian Airlines
Sun, May 17 - Mon, May 25
CAE
Columbia
BRU
Brussels
$760 Roundtrip, found 4 days ago
$760
Roundtrip
found 4 days ago
Select Scandinavian Airlines flight, departing Sun, May 17 from Columbia to Brussels, returning Mon, May 25, priced at $760 found 4 days ago
Lufthansa
Fri, Nov 28 - Fri, Dec 5
CAE
Columbia
BRU
Brussels
$770 Roundtrip, just found
$770
Roundtrip
just found
Select Lufthansa flight, departing Fri, Nov 28 from Columbia to Brussels, returning Fri, Dec 5, priced at $770 just found
Lufthansa
Fri, Nov 28 - Fri, Dec 5
CAE
Columbia
BRU
Brussels
$776 Roundtrip, just found
$776
Roundtrip
just found
Select Lufthansa flight, departing Fri, Nov 28 from Columbia to Brussels, returning Fri, Dec 5, priced at $776 just found
Lufthansa
Fri, Nov 28 - Fri, Dec 5
CAE
Columbia
BRU
Brussels
$781 Roundtrip, just found
$781
Roundtrip
just found
Select Lufthansa flight, departing Fri, Nov 28 from Columbia to Brussels, returning Fri, Dec 5, priced at $781 just found

Frequently asked questions

How much does a flight from Columbia Metropolitan Airport (CAE) to Brussels - National Airport (BRU) cost?
Secure a cheap one-way flight from $450 or cheap return flight from $650 from Columbia Metropolitan Airport (CAE) to Brussels - National Airport (BRU) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Columbia Metropolitan Airport (CAE) to Brussels - National Airport (BRU)?
November is the most affordable month to fly from CAE to BRU. Timing your trip outside of the busy season is often the key to scoring lower fares.
What is the cheapest airline that flies from Columbia Metropolitan Airport (CAE) to Brussels - National Airport (BRU)?
To find the cheapest airline flying from CAE to BRU, use Expedia's filter tool. Customize your search based on what's important to you, such as preferred carriers and cabin class. You can then sort your results by "Price (lowest to highest)" to discover the cheapest flight right away.
How many flights per day from Columbia Metropolitan Airport (CAE) to Brussels - National Airport (BRU)?
Direct flights from Columbia Metropolitan Airport (CAE) to Brussels - National Airport (BRU) aren't available daily, so you'll have to take a flight with a layover. Explore your options with Expedia's filters. Enter your dates and select either "1 Stop" or "2+ Stops."
What day of the week has the most flights from CAE to BRU?
Friday is generally the busiest day for flights, while Tuesday is often the quietest.* Remember that flight schedules can change depending on a range of factors, including the carrier and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Columbia Metropolitan Airport (CAE) to Brussels - National Airport (BRU)?
To avoid possible delays on the Columbia Metropolitan Airport (CAE) to Brussels - National Airport (BRU) route, aim to fly before 3 PM. Later departures have a 22% higher chance of cancellation.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Columbia Metropolitan Airport (CAE) to Brussels - National Airport (BRU) last-minute?
Last-minute bookings from CAE to BRU are typically more expensive. To lock in the cheapest rates, start looking for flights well in advance. That being said, if your travel plans are flexible, it's possible to score a cheap fare just before your departure.
Is it cheaper to book a CAE to BRU flight and hotel package?
Compared with arranging flights and hotels separately, booking a CAE to BRU flight and hotel package with Expedia could result in significant savings. What's more, having everything in one place will take the stress out of planning your trip. Simply pick your flights and select from our wide range of stays, then customize your trip with extras like activities, tours and car rentals.
Can I cancel or change the date of my flight from Columbia Metropolitan Airport (CAE) to Brussels - National Airport (BRU)?
Generally, it's possible to cancel or reschedule your CAE to BRU flight. However, if it's been more than 24 hours since booking, additional charges may apply. Check your airline's policies in your itinerary to see what changes are allowed and whether any costs are involved. You'll also find more information on our Customer Service portal.

Travel information

Origin airport
Columbia Metropolitan
Destination airport
Brussels - National
Airlines serving
Brussels Airlines, Lufthansa, Scandinavian Airlines
Roundtrip price
$650
Distance
4265 mi

Book with confidence

Columbia to Brussels Flights

The cheapest times to fly from Columbia to Brussels

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Columbia to Brussels are during the month of November. You can find some of the cheapest flights from Columbia to Brussels with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Columbia to Brussels

Sunday is one of the best days to book for cheap flights from Columbia to Brussels: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Columbia to Brussels

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Columbia to Brussels in 2025. You can also book with separate airlines for your outbound and return journeys, from $450 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Columbia to Brussels flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Columbia to Brussels airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Columbia to Brussels Flights

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*Available to One Key members.