$239 Cheap Flights from Columbia (CAE) to Key West (EYW)

View $239 flight on Wed, Oct 15, 2025Opens in a new window

Popular airlines from Columbia Metropolitan Airport (CAE) to Key West Intl. Airport (EYW)

  • Plan, book, fly with confidence

  • trending down icon

    Be in the know

    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon

    Book smarter

    Save up to 30% on select hotels after you book a flight*
  • one key icon

    Earn twice

    Earn your airline miles on top of our OneKeyCash
    Learn about One Key

Cheap Flights from Columbia to Key West (CAE-EYW)

Prices were available within the past 7 days and start at $239 for one-way flights and $249 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Tue, Jan 27 - Tue, Feb 3
CAE
Columbia
EYW
Key West
$249 Roundtrip, found 1 hour ago
$249
Roundtrip
found 1 hour ago
Select American Airlines flight, departing Tue, Jan 27 from Columbia to Key West, returning Tue, Feb 3, priced at $249 found 1 hour ago
Delta
Tue, Sep 30 - Thu, Oct 9
CAE
Columbia
EYW
Key West
$254 Roundtrip, found 2 days ago
$254
Roundtrip
found 2 days ago
Select Delta flight, departing Tue, Sep 30 from Columbia to Key West, returning Thu, Oct 9, priced at $254 found 2 days ago
American Airlines
Tue, Jan 27 - Tue, Feb 3
CAE
Columbia
EYW
Key West
$266 Roundtrip, found 1 hour ago
$266
Roundtrip
found 1 hour ago
Select American Airlines flight, departing Tue, Jan 27 from Columbia to Key West, returning Tue, Feb 3, priced at $266 found 1 hour ago
Delta
Tue, Sep 30 - Wed, Oct 15
CAE
Columbia
EYW
Key West
$271 Roundtrip, found 2 days ago
$271
Roundtrip
found 2 days ago
Select Delta flight, departing Tue, Sep 30 from Columbia to Key West, returning Wed, Oct 15, priced at $271 found 2 days ago
Delta
Mon, Jan 26 - Thu, Feb 12
CAE
Columbia
EYW
Key West
$274 Roundtrip, found 2 days ago
$274
Roundtrip
found 2 days ago
Select Delta flight, departing Mon, Jan 26 from Columbia to Key West, returning Thu, Feb 12, priced at $274 found 2 days ago
Delta
Mon, Sep 22 - Thu, Oct 9
CAE
Columbia
EYW
Key West
$279 Roundtrip, found 2 days ago
$279
Roundtrip
found 2 days ago
Select Delta flight, departing Mon, Sep 22 from Columbia to Key West, returning Thu, Oct 9, priced at $279 found 2 days ago
Delta
Tue, Feb 3 - Wed, Feb 11
CAE
Columbia
EYW
Key West
$283 Roundtrip, found 3 days ago
$283
Roundtrip
found 3 days ago
Select Delta flight, departing Tue, Feb 3 from Columbia to Key West, returning Wed, Feb 11, priced at $283 found 3 days ago
Delta
Wed, Jan 28 - Fri, Feb 6
CAE
Columbia
EYW
Key West
$291 Roundtrip, found 2 days ago
$291
Roundtrip
found 2 days ago
Select Delta flight, departing Wed, Jan 28 from Columbia to Key West, returning Fri, Feb 6, priced at $291 found 2 days ago
Delta
Tue, Jan 27 - Tue, Feb 3
CAE
Columbia
EYW
Key West
$294 Roundtrip, found 1 hour ago
$294
Roundtrip
found 1 hour ago
Select Delta flight, departing Tue, Jan 27 from Columbia to Key West, returning Tue, Feb 3, priced at $294 found 1 hour ago
United
Wed, Feb 11 - Thu, Feb 26
CAE
Columbia
EYW
Key West
$433 Roundtrip, found 5 days ago
$433
Roundtrip
found 5 days ago
Select United flight, departing Wed, Feb 11 from Columbia to Key West, returning Thu, Feb 26, priced at $433 found 5 days ago

Find the cheapest month to fly from Columbia (CAE) to Key West (EYW)

May is typically the cheapest month to fly

From $248 - $608 per traveler.
Flights from Columbia (CAE) to Key West (EYW)
Origin airport
Columbia Metropolitan
Destination airport
Key West Intl.
Airlines serving
American Airlines, Delta, United
Roundtrip price
$248
Distance
650 mi

Columbia to Key West Flights

The cheapest times to fly from Columbia to Key West

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Columbia to Key West are during the month of January. You can find some of the cheapest flights from Columbia to Key West with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Columbia to Key West

Sunday is one of the best days to book for cheap flights from Columbia to Key West: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Columbia to Key West

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Columbia to Key West in 2025. You can also book with separate airlines for your outbound and return journeys, from $239 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Columbia to Key West flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Columbia to Key West airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Columbia Metropolitan Airport (CAE) to Key West Intl. Airport (EYW) cost?
Snag a cheap one-way flight from $239 or cheap return flight from $249 from Columbia Metropolitan Airport (CAE) to Key West Intl. Airport (EYW) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Columbia Metropolitan Airport (CAE) to Key West Intl. Airport (EYW)?
January is the cheapest month to fly from CAE to EYW. Planning your trip for the off-season is often the key to scoring lower fares.
What is the cheapest airline that flies from Columbia Metropolitan Airport (CAE) to Key West Intl. Airport (EYW)?
To find the cheapest airline that'll fly you from CAE to EYW, use Expedia's filter tool. Customize your search based on what's important to you, such as preferred carriers and seat class. You can then sort your results by "Price (lowest to highest)" to see the most affordable options first.
How many flights per day from Columbia Metropolitan Airport (CAE) to Key West Intl. Airport (EYW)?
You'll need to catch a flight with a layover if you're traveling from Columbia Metropolitan Airport (CAE) to Key West Intl. Airport (EYW). There are no daily direct flights on this route. However, just filter your search to include one or more stops to find an option that works for you.
What day of the week has the most flights from CAE to EYW?
Friday is generally the busiest day for flights, while Tuesday tends to be the quietest.* Keep in mind that flight schedules can change based on various factors, such as the airline and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Columbia Metropolitan Airport (CAE) to Key West Intl. Airport (EYW)?
Opt for a flight from Columbia Metropolitan Airport (CAE) to Key West Intl. Airport (EYW) that leaves before 3 PM to reduce the risk of cancellations. Later departures have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Columbia Metropolitan Airport (CAE) to Key West Intl. Airport (EYW) last-minute?
Booking your ticket from CAE to EYW just before your getaway is generally more expensive. However, if you're flexible with your departure dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a CAE to EYW flight and hotel package?
Compared with arranging flights and hotels separately, booking a CAE to EYW flight and hotel package with Expedia could lead to significant savings. Better still, managing everything in one place takes the hassle out of travel planning. Just secure your flights and choose from our wide range of hotels, then customize your trip with other add-ons like activities and car rentals.
Can I cancel or change the date of my flight from Columbia Metropolitan Airport (CAE) to Key West Intl. Airport (EYW)?
Typically, you can cancel or reschedule your CAE to EYW flight. However, there may be additional fees, especially if you made your booking over 24 hours ago. Double-check your itinerary for the airline's fees and rules on flight changes, or if you'd like further information, go to our Customer Service portal.

Explore a world of travel with Expedia

*Available to One Key members.