$53 Cheap Flights from Charleston (CHS) to Indianapolis (IND)

View $53 flight on Tue, Nov 11, 2025Opens in a new window

Popular airlines from Charleston Intl. Airport (CHS) to Indianapolis Intl. Airport (IND)

Cheap Flights from Charleston to Indianapolis (CHS-IND)

Prices were available within the past 7 days and start at $53 for one-way flights and $159 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Spirit Airlines
Tue, Dec 2 - Fri, Dec 5
CHS
Charleston
IND
Indianapolis
$159 Roundtrip, found 2 days ago
$159
Roundtrip
found 2 days ago
Select Spirit Airlines flight, departing Tue, Dec 2 from Charleston to Indianapolis, returning Fri, Dec 5, priced at $159 found 2 days ago
Spirit Airlines
Mon, Nov 24 - Thu, Dec 4
CHS
Charleston
IND
Indianapolis
$174 Roundtrip, found 2 days ago
$174
Roundtrip
found 2 days ago
Select Spirit Airlines flight, departing Mon, Nov 24 from Charleston to Indianapolis, returning Thu, Dec 4, priced at $174 found 2 days ago
Spirit Airlines
Tue, Nov 18 - Mon, Nov 24
CHS
Charleston
IND
Indianapolis
$187 Roundtrip, found 2 hours ago
$187
Roundtrip
found 2 hours ago
Select Spirit Airlines flight, departing Tue, Nov 18 from Charleston to Indianapolis, returning Mon, Nov 24, priced at $187 found 2 hours ago
Spirit Airlines
Thu, Jan 8 - Sat, Jan 10
CHS
Charleston
IND
Indianapolis
$195 Roundtrip, found 6 days ago
$195
Roundtrip
found 6 days ago
Select Spirit Airlines flight, departing Thu, Jan 8 from Charleston to Indianapolis, returning Sat, Jan 10, priced at $195 found 6 days ago
Southwest Airlines
Wed, Feb 11 - Sat, Feb 14
CHS
Charleston
IND
Indianapolis
$198 Roundtrip, found 6 days ago
$198
Roundtrip
found 6 days ago
Select Southwest Airlines flight, departing Wed, Feb 11 from Charleston to Indianapolis, returning Sat, Feb 14, priced at $198 found 6 days ago
Spirit Airlines
Tue, Dec 2 - Thu, Dec 4
CHS
Charleston
IND
Indianapolis
$199 Roundtrip, found 6 days ago
$199
Roundtrip
found 6 days ago
Select Spirit Airlines flight, departing Tue, Dec 2 from Charleston to Indianapolis, returning Thu, Dec 4, priced at $199 found 6 days ago
Spirit Airlines
Tue, Nov 11 - Tue, Nov 18
CHS
Charleston
IND
Indianapolis
$201 Roundtrip, found 16 hours ago
$201
Roundtrip
found 16 hours ago
Select Spirit Airlines flight, departing Tue, Nov 11 from Charleston to Indianapolis, returning Tue, Nov 18, priced at $201 found 16 hours ago
United
Wed, Feb 11 - Sat, Feb 14
CHS
Charleston
IND
Indianapolis
$224 Roundtrip, found 6 days ago
$224
Roundtrip
found 6 days ago
Select United flight, departing Wed, Feb 11 from Charleston to Indianapolis, returning Sat, Feb 14, priced at $224 found 6 days ago
Delta
Wed, Dec 31 - Thu, Jan 1
CHS
Charleston
IND
Indianapolis
$247 Roundtrip, found 1 day ago
$247
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, Dec 31 from Charleston to Indianapolis, returning Thu, Jan 1, priced at $247 found 1 day ago
American Airlines
Tue, Dec 2 - Fri, Dec 5
CHS
Charleston
IND
Indianapolis
$261 Roundtrip, found 2 days ago
$261
Roundtrip
found 2 days ago
Select American Airlines flight, departing Tue, Dec 2 from Charleston to Indianapolis, returning Fri, Dec 5, priced at $261 found 2 days ago

Find the cheapest month to fly from Charleston (CHS) to Indianapolis (IND)

March is typically the cheapest month to fly

From $131 - $429 per traveler.

Alternative airports near Indianapolis

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Indianapolis Intl. IND. Cheapest and Closest option available. Average driving time to city center is 19 minutes. Flights from $331
IND
Indianapolis Intl.
CheapestClosest
Average driving time to city center19 min
Flights from $331

Frequently asked questions

How much does a flight from Charleston Intl. Airport (CHS) to Indianapolis Intl. Airport (IND) cost?
Lock in a cheap one-way flight from $53 or cheap return flight from $159 from Charleston Intl. Airport (CHS) to Indianapolis Intl. Airport (IND) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Charleston Intl. Airport (CHS) to Indianapolis Intl. Airport (IND)?
December is the most affordable month to fly from CHS to IND. Timing your trip outside of the busy season is often the key to landing a great deal.
What is the cheapest airline that flies from Charleston Intl. Airport (CHS) to Indianapolis Intl. Airport (IND)?
To find the cheapest airline that'll fly you from CHS to IND, use Expedia's filter tool. Customize your search based on what's important to you, such as preferred carriers and flight duration. You can then sort your results by "Price (lowest to highest)" to list the most affordable options first.
How many flights per day from Charleston Intl. Airport (CHS) to Indianapolis Intl. Airport (IND)?
There aren't any daily nonstop flights from Charleston Intl. Airport (CHS) to Indianapolis Intl. Airport (IND). But you can choose flights with layovers. Filter your search results on Expedia to include one or two stops, and you'll be cruising above the clouds before you know it.
What day of the week has the most flights from CHS to IND?
Generally you'll find the largest variety of flight choices on a Friday. Tuesdays are often the quietest.* But this can vary based on the time of year, carrier and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What airline has the least delays from CHS to IND?
With 86% of journeys typically arriving as scheduled, United Airlines has the best on-time performance for nonstop flights from Charleston Intl. Airport (CHS) to Indianapolis Intl. Airport (IND). To monitor your flight status and get notifications if anything changes, use the Expedia App.
What is the best time to fly from Charleston Intl. Airport (CHS) to Indianapolis Intl. Airport (IND)?
To avoid potential delays on the Charleston Intl. Airport (CHS) to Indianapolis Intl. Airport (IND) route, aim to travel before 3 PM. Later flights are 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Charleston Intl. Airport (CHS) to Indianapolis Intl. Airport (IND) last-minute?
Last-minute fares from CHS to IND are usually more expensive. For the best rates, start looking for flights as early as possible. That being said, if you're flexible with your travel dates, it's possible to find a cheap ticket right before you leave.
Is it cheaper to book a CHS to IND flight and hotel package?
Securing a CHS to IND flight and hotel package tends to be cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your travels in one place. Pick from our impressive range of accommodations and then add activities, car rentals and flights to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Charleston Intl. Airport (CHS) to Indianapolis Intl. Airport (IND)?
You can usually cancel or reschedule your CHS to IND flight. However, if it's been more than 24 hours since booking, additional charges may apply. Check your airline's policies in your itinerary to see what changes are possible and if any costs are involved. You'll also find more details on our Customer Service portal.

Travel information

Origin airport
Charleston Intl.
Destination airport
Indianapolis Intl.
Airlines serving
American Airlines, Delta, Southwest Airlines, United
Roundtrip price
$159
Distance
586 mi

Book with confidence

Charleston to Indianapolis Flights

The cheapest times to fly from Charleston to Indianapolis

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Charleston to Indianapolis are during the month of December. You can find some of the cheapest flights from Charleston to Indianapolis with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Charleston to Indianapolis

Sunday is one of the best days to book for cheap flights from Charleston to Indianapolis: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Charleston to Indianapolis

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Charleston to Indianapolis in 2025. You can also book with separate airlines for your outbound and return journeys, from $53 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Charleston to Indianapolis flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Charleston to Indianapolis airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Charleston to Indianapolis Flights

Explore a world of travel with Expedia

*Available to One Key members.