$328 Cheap Flights from Charlotte (CLT) to Tupelo (TUP)

View $328 flight on Wed, Nov 12, 2025Opens in a new window

Popular airlines from Charlotte-Douglas Intl. Airport (CLT) to Tupelo, MS (TUP-Tupelo Regional)

Cheap Flights from Charlotte to Tupelo (CLT-TUP)

Prices were available within the past 7 days and start at $328 for one-way flights and $287 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Sat, Dec 6 - Thu, Jan 1
CLT
Charlotte
TUP
Tupelo
$287 Roundtrip, found 1 day ago
$287
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sat, Dec 6 from Charlotte to Tupelo, returning Thu, Jan 1, priced at $287 found 1 day ago
American Airlines
Thu, Jan 15 - Sun, Jan 18
CLT
Charlotte
TUP
Tupelo
$326 Roundtrip, found 3 days ago
$326
Roundtrip
found 3 days ago
Select American Airlines flight, departing Thu, Jan 15 from Charlotte to Tupelo, returning Sun, Jan 18, priced at $326 found 3 days ago
American Airlines
Sat, Dec 6 - Thu, Jan 1
CLT
Charlotte
TUP
Tupelo
$335 Roundtrip, found 1 day ago
$335
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sat, Dec 6 from Charlotte to Tupelo, returning Thu, Jan 1, priced at $335 found 1 day ago
American Airlines
Thu, Jan 15 - Sun, Jan 18
CLT
Charlotte
TUP
Tupelo
$342 Roundtrip, found 3 days ago
$342
Roundtrip
found 3 days ago
Select American Airlines flight, departing Thu, Jan 15 from Charlotte to Tupelo, returning Sun, Jan 18, priced at $342 found 3 days ago
American Airlines
Fri, Feb 6 - Sun, Feb 8
CLT
Charlotte
TUP
Tupelo
$360 Roundtrip, found 1 hour ago
$360
Roundtrip
found 1 hour ago
Select American Airlines flight, departing Fri, Feb 6 from Charlotte to Tupelo, returning Sun, Feb 8, priced at $360 found 1 hour ago
American Airlines
Fri, Dec 12 - Sun, Dec 14
CLT
Charlotte
TUP
Tupelo
$376 Roundtrip, found 22 hours ago
$376
Roundtrip
found 22 hours ago
Select American Airlines flight, departing Fri, Dec 12 from Charlotte to Tupelo, returning Sun, Dec 14, priced at $376 found 22 hours ago
United
Tue, Dec 9 - Sat, Dec 13
CLT
Charlotte
TUP
Tupelo
$383 Roundtrip, found 22 hours ago
$383
Roundtrip
found 22 hours ago
Select United flight, departing Tue, Dec 9 from Charlotte to Tupelo, returning Sat, Dec 13, priced at $383 found 22 hours ago
United
Sun, Dec 14 - Mon, Dec 15
CLT
Charlotte
TUP
Tupelo
$396 Roundtrip, found 22 hours ago
$396
Roundtrip
found 22 hours ago
Select United flight, departing Sun, Dec 14 from Charlotte to Tupelo, returning Mon, Dec 15, priced at $396 found 22 hours ago
United
Tue, Feb 3 - Tue, Feb 10
CLT
Charlotte
TUP
Tupelo
$397 Roundtrip, found 1 hour ago
$397
Roundtrip
found 1 hour ago
Select United flight, departing Tue, Feb 3 from Charlotte to Tupelo, returning Tue, Feb 10, priced at $397 found 1 hour ago
United
Tue, Feb 3 - Mon, Feb 9
CLT
Charlotte
TUP
Tupelo
$408 Roundtrip, found 1 hour ago
$408
Roundtrip
found 1 hour ago
Select United flight, departing Tue, Feb 3 from Charlotte to Tupelo, returning Mon, Feb 9, priced at $408 found 1 hour ago

Alternative airports near Tupelo

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Tupelo Regional TUP. Cheapest and Closest option available. Average driving time to city center is 8 minutes. Flights from $546
TUP
Tupelo Regional
CheapestClosest
Average driving time to city center8 min
Flights from $546

Frequently asked questions

How much does a flight from Charlotte-Douglas Intl. Airport (CLT) to Tupelo Regional Airport (TUP) cost?
Snag a cheap one-way flight from $328 or cheap return flight from $287 from Charlotte-Douglas Intl. Airport (CLT) to Tupelo Regional Airport (TUP) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Charlotte-Douglas Intl. Airport (CLT) to Tupelo Regional Airport (TUP)?
Planning your getaway for December is a great way to save, as it's the cheapest month for flights between CLT and TUP. You'll usually find the lowest prices during off-peak months.
What is the cheapest airline that flies from Charlotte-Douglas Intl. Airport (CLT) to Tupelo Regional Airport (TUP)?
Expedia's filter tool lets you easily compare different airlines, departure times and fares all in one place. Customize the search to your preferences, then sort by "Price (lowest to highest)" to see which carrier offers the cheapest CLT to TUP flight.
How many flights per day from Charlotte-Douglas Intl. Airport (CLT) to Tupelo Regional Airport (TUP)?
There are no daily direct flights from Charlotte-Douglas Intl. Airport (CLT) to Tupelo Regional Airport (TUP). But you can book flights with layovers. Filter your search on Expedia to include one or two stops, and you'll be cruising above the clouds in no time at all.
What day of the week has the most flights from CLT to TUP?
Generally you'll find the most flight options available on a Friday. Tuesdays are often the quietest.* However, this can change based on the airline, season and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Charlotte-Douglas Intl. Airport (CLT) to Tupelo Regional Airport (TUP)?
To touch down at Tupelo Regional Airport (TUP) on schedule, book a flight that takes off from Charlotte-Douglas Intl. Airport (CLT) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Charlotte-Douglas Intl. Airport (CLT) to Tupelo Regional Airport (TUP) last-minute?
Last-minute fares from CLT to TUP are typically more expensive. To secure the best rates, start looking for flights ahead of time. That said, if you can play around with your travel dates, you may land a cheap fare just before your departure.
Is it cheaper to book a CLT to TUP flight and hotel package?
Compared with arranging hotels and flights separately, booking a CLT to TUP flight and hotel package with Expedia could result in significant savings. Better yet, having it all in one place will take the stress out of planning your trip. Simply secure your flights and choose from our extensive range of stays, then tailor your trip with other add-ons like tours, car rentals and activities.
Can I cancel or change the date of my flight from Charlotte-Douglas Intl. Airport (CLT) to Tupelo Regional Airport (TUP)?
If you reserved your CLT to TUP flight in the last 24 hours, you may be able to cancel or modify it without any fees. Depending on the airline and the type of ticket you purchased, additional charges may apply for changes beyond that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal for further details.

Travel information

Origin airport
Charlotte-Douglas Intl.
Destination airport
Tupelo Regional
Roundtrip price
$287
Distance
448 mi

Book with confidence

Charlotte to Tupelo Flights

The cheapest times to fly from Charlotte to Tupelo

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Charlotte to Tupelo are during the month of December. You can find some of the cheapest flights from Charlotte to Tupelo with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Charlotte to Tupelo

Sunday is one of the best days to book for cheap flights from Charlotte to Tupelo: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Charlotte to Tupelo

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Charlotte to Tupelo in 2025. You can also book with separate airlines for your outbound and return journeys, from $328 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Charlotte to Tupelo flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Charlotte to Tupelo airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Charlotte to Tupelo Flights

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*Available to One Key members.