$394 Cheap Flights from Denver (DEN) to Cusco (CUZ)

View $394 flight on Sat, Oct 24, 2026Opens in a new window

Popular airlines from Denver Intl. Airport (DEN) to Alejandro Velasco Astete Intl. Airport (CUZ)

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Cheap Flights from Denver to Cusco (DEN-CUZ)

Prices were available within the past 7 days and start at $394 for one-way flights and $749 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

United
Wed, Feb 3 - Wed, Feb 17
DEN
Denver
CUZ
Cusco
$749 Roundtrip, found 1 day ago
$749
Roundtrip
found 1 day ago
Select United flight, departing Wed, Feb 3 from Denver to Cusco, returning Wed, Feb 17, priced at $749 found 1 day ago
United
Fri, Oct 30 - Wed, Nov 4
DEN
Denver
CUZ
Cusco
$759 Roundtrip, found 5 hours ago
$759
Roundtrip
found 5 hours ago
Select United flight, departing Fri, Oct 30 from Denver to Cusco, returning Wed, Nov 4, priced at $759 found 5 hours ago
United
Sat, Oct 24 - Sat, Oct 31
DEN
Denver
CUZ
Cusco
$787 Roundtrip, found 1 hour ago
$787
Roundtrip
found 1 hour ago
Select United flight, departing Sat, Oct 24 from Denver to Cusco, returning Sat, Oct 31, priced at $787 found 1 hour ago
United
Fri, Oct 30 - Wed, Nov 4
DEN
Denver
CUZ
Cusco
$802 Roundtrip, found 5 hours ago
$802
Roundtrip
found 5 hours ago
Select United flight, departing Fri, Oct 30 from Denver to Cusco, returning Wed, Nov 4, priced at $802 found 5 hours ago
United
Wed, Mar 17 - Thu, Mar 25
DEN
Denver
CUZ
Cusco
$834 Roundtrip, found 3 days ago
$834
Roundtrip
found 3 days ago
Select United flight, departing Wed, Mar 17 from Denver to Cusco, returning Thu, Mar 25, priced at $834 found 3 days ago
United
Sat, Oct 24 - Sat, Oct 31
DEN
Denver
CUZ
Cusco
$847 Roundtrip, found 1 hour ago
$847
Roundtrip
found 1 hour ago
Select United flight, departing Sat, Oct 24 from Denver to Cusco, returning Sat, Oct 31, priced at $847 found 1 hour ago
American Airlines
Sun, Nov 1 - Sun, Nov 15
DEN
Denver
CUZ
Cusco
$860 Roundtrip, just found
$860
Roundtrip
just found
Select American Airlines flight, departing Sun, Nov 1 from Denver to Cusco, returning Sun, Nov 15, priced at $860 just found
Delta
Sat, Oct 24 - Sat, Oct 31
DEN
Denver
CUZ
Cusco
$861 Roundtrip, found 1 hour ago
$861
Roundtrip
found 1 hour ago
Select Delta flight, departing Sat, Oct 24 from Denver to Cusco, returning Sat, Oct 31, priced at $861 found 1 hour ago
LATAM Airlines Group
Sat, Oct 24 - Sat, Oct 31
DEN
Denver
CUZ
Cusco
$895 Roundtrip, found 1 hour ago
$895
Roundtrip
found 1 hour ago
Select LATAM Airlines Group flight, departing Sat, Oct 24 from Denver to Cusco, returning Sat, Oct 31, priced at $895 found 1 hour ago
avianca
Sat, Oct 31 - Sun, Nov 8
DEN
Denver
CUZ
Cusco
$1,143 Roundtrip, found 4 days ago
$1,143
Roundtrip
found 4 days ago
Select avianca flight, departing Sat, Oct 31 from Denver to Cusco, returning Sun, Nov 8, priced at $1,143 found 4 days ago

Alternative airports near Cusco

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Alejandro Velasco Astete Intl. CUZ. Cheapest and Closest option available. Average driving time to city center is 4 minutes. Flights from $1,240
CUZ
Alejandro Velasco Astete Intl.
CheapestClosest
Average driving time to city center4 min
Flights from $1,240

What you need to know for your flight from Denver Intl. to Alejandro Velasco Astete Intl.

Denver (DEN) to Cusco (CUZ) at a glance

Travel to Cusco (CUZ) from Denver (DEN) with a range of airlines on this international long-haul route. Compare choices among full-service carriers to discover the itinerary that aligns with your budget, schedule, and travel preferences as you prepare to explore Cusco's renowned landmarks and neighborhoods. Here are the essential details for flights departing from Denver International Airport (DEN) to Alejandro Velasco Astete International Airport (CUZ).

  • Fastest flight duration: around 11 hours in-flight, plus roughly 5 hours total layover with two or more stops
  • Route distance: roughly 4,200 miles (6,760 km)
  • Flights per week: around 8 departures on average
  • Typical fares (one-way): economy tickets often range from $265–$770, depending on seasonality and how far ahead you book

Flights from Denver International Airport (DEN) to Alejandro Velasco Astete International Airport (CUZ)

Based on the latest traveler bookings, here are the top airlines favored for flights from Denver to Cusco, particularly those offering multi-stop options. Common layovers include Jorge Chávez International Airport (LIM) with a 2h 30m stop, Hartsfield-Jackson Atlanta International Airport (ATL) at around 1h 45m, and El Dorado International Airport (BOG) with a 2h 45m layover. This flexibility allows you to balance price, overall travel time, and cabin class to create the ideal itinerary.

  • Delta: This full-service airline provides multi-stop options, with one-way prices generally falling between $295 and $840. Delta makes up about 41% of flights on this route, featuring an in-flight duration of 11 hours and a total travel time of approximately 16 hours, including layovers.
  • United: As a full-service carrier, United offers multi-stop service with one-way fares usually ranging from $265 to $675. Representing around 26% of departures on this route, the airline's flight time is 11 hours, and the overall journey takes about 16 hours, including layovers.
  • LATAM Airlines Group: LATAM is a full-service airline that provides multi-stop routes, with one-way ticket prices typically between $330 and $815. Accounting for roughly 21% of departures on this route, the flight duration is 11 hours, resulting in a total travel time of around 16 hours, including layovers.
  • American Airlines: This full-service carrier also offers multi-stop services, with one-way fares that usually range from $360 to $575. American Airlines makes up approximately 10% of flights on this route, featuring an in-flight time of 11 hours and a total journey duration of about 16 hours, including layovers.

Best time to fly from Denver (DEN) to Cusco (CUZ)

The most popular months for travelers flying from Denver to Cusco are January, March, and April, when peak temperatures in Cusco reach up to 50.2°F in January. If you prefer quieter travel, consider February, the least busy time to visit with temperatures around 50°F and typically the lowest average one-way fare (around $297). Flight availability peaks in September, with approximately 11 flights per week, making it easier to find convenient departure times.

  • Cheapest time to fly: February usually offers good deals with average one-way fare around $297, roughly 36% cheaper than the yearly average.
  • Most flight options: September has the highest number of flights from Denver to Cusco, with approximately 11 flights per week, giving you more flexibility in scheduling your trip.
calendar iconMonthtemperature iconTemperaturecrowd level iconDemandflights iconWeekly Flightsprice iconAverage one-way Fare
January50.2°F (10.1°C)High7$421
February50.0°F (10.0°C)Low7$297
March49.8°F (9.9°C)High9$517
April49.6°F (9.8°C)High8$397
May48.6°F (9.2°C)Average8$557
June47.7°F (8.7°C)Average7$462
July47.8°F (8.8°C)Average9$627
August49.5°F (9.7°C)Average9$416
September51.1°F (10.6°C)Average11$465
October52.2°F (11.2°C)Average8$449
November52.5°F (11.4°C)Low10$433
December51.1°F (10.6°C)Low7$584

*Average one-way fare is based on Expedia flight booking data from January 2025 to April 2026 for the specified route and travel class and may change depending on availability, dates, and demand.

Alternative routes from Denver (DEN) to Cusco (CUZ)

  • Denver to Cusco (APA-CUZ): Centennial Airport (APA) is located approximately 21 miles from Denver International Airport (DEN).
  • Boulder to Cusco (WBU-CUZ): Boulder Municipal Airport (WBU) lies around 32 miles from Denver International Airport (DEN).
  • Colorado Springs to Cusco (COS-CUZ): Colorado Springs Airport (COS) is about 73 miles distant from Denver International Airport (DEN).

How to find the best prices for flights from Denver (DEN) to Cusco (CUZ)

Getting some of the best deals on flights from Denver to Cusco is all about timing and flexibility. Here are some key tips to help you save:

  1. Best times to book and fly: cheaper fares are typically available when booking within two weeks, although most travelers tend to book at least two months in advance. Afternoon departures, between 12 p.m. and 6 p.m., usually offer lower prices and are the most popular times to fly. Additionally, flying on Monday generally provides cheaper options, while Friday remains the busiest travel day.
  2. Set up price alerts: stay updated on price changes by using Expedia's Price Tracker. Receive alerts when fares drop for your selected route.
  3. Bundle and save: bundle your flight and hotel to save on Expedia, or unlock a hotel deal after booking your flight.* Find Cusco hotel and flight deals.
  4. Compare flight options: use Expedia's search tool to compare airlines, routes, direct vs. non-direct flights, and flight times. You can also sort by price to find the most affordable options.
  5. Stay flexible with dates: being open to different travel days can sometimes help you find better prices on flights and hotels.
  6. Think about luggage: nowadays, it's important to check the airline's baggage policies to find the best value. That may be paying for an additional carry-on bag or booking a ticket with checked luggage included. Either way, double-check your allowance before confirming your booking to avoid excess baggage fees at the airport.

*Members only. Savings vary and are not available on all bundles. Select hotels.

Arriving at Alejandro Velasco Astete International Airport from Denver International Airport

Cusco welcomes travelers from Denver with a range of transport options based on price, convenience, and proximity. Here's how to reach Cusco efficiently:

  • Hotel transfer: Transfers offer a convenient way to reach your hotel in Cusco, with options including free hotel shuttles and private rides, which can be arranged in advance with your hotel.
  • Car rental: Renting a car from Alejandro Velasco Astete International Airport is a great option if you plan to explore and sightsee beyond the city. Browse cheap car rentals at Alejandro Velasco Astete International Airport on Expedia.
  • Taxi/ride-hailing: Taxis and ride-hailing services may be available from designated pickup areas outside the terminal, check locally on arrival.
  • Public transportation: From Alejandro Velasco Astete International Airport, Cusco Bus Station (a bus station) is located about 1.6 miles away by car, while Cusco Wanchaq Station (a train station) is approximately 2.5 miles away by car. For those needing to travel by sea, Cusco Seaport (a seaport) is around 3.2 miles from the airport, typically reached by car.

Frequently asked questions

How much does a flight from Denver, CO (DEN-Denver Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.) cost?
You can find cheap one-way flights from $394 and cheap return flights from $749 Denver, CO (DEN-Denver Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.) with Expedia. One-way flights generally range between $340 and $2491, and roundtrip flights usually range from $768 to $4077. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Denver, CO (DEN-Denver Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Denver, CO (DEN-Denver Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.)?
February is the cheapest month to fly from Denver, CO (DEN) to Cusco (CUZ), with average round-trip fares around $681. This is about 31% lower than the average price throughout the year, as February often sees reduced travel demand. Other budget-friendly months include January and November.*Averages based on flights available on Expedia in the last year.
Which airlines fly direct from Denver, CO (DEN-Denver Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.)?
Enter DEN to CUZ and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Denver, CO (DEN-Denver Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.)?
JetBlue Airways is one of the cheapest airlines offering connecting flights from Denver, CO (DEN) to Cusco (CUZ), with round-trip tickets starting from around $786 with a layover in John F. Kennedy Intl. (JFK). Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.*Prices based on flights available on Expedia in the last year.
How do I find cheap flights from Denver, CO (DEN-Denver Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.)?
To find a cheap flight from Denver, CO (DEN-Denver Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Denver, CO (DEN-Denver Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.)?
For flights from Denver, CO (DEN) to Cusco (CUZ), February and January are the best months to travel. Return flights during these months average around $681. January is great for those looking to escape the winter, while February offers a chance to experience Cusco's vibrant culture before the peak tourist season.*Prices based on flights available on Expedia in the last year.
What is the earliest flight from Denver, CO (DEN-Denver Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.)?
The earliest flight from Denver (DEN) to Cusco (CUZ) typically leaves at 12:15 AM, operated by American Airlines. This seasonal service is available in November, allowing you to maximize your time exploring the wonders of Peru. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from Denver, CO (DEN-Denver Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.)?
The most popular departure times for flights from Denver, CO (DEN) to Cusco (CUZ) are in the late afternoon, from 3pm to 6pm. About 48% of passengers prefer this time window. Many major carriers, including Delta and United Airlines, offer flights during this period. This timing is popular because it allows you to travel after the day's activities, making for a more relaxed journey.
How long does it take to fly from Denver, CO (DEN-Denver Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.)?
A flight from DEN to CUZ with a layover takes around 20 hours, with the route covering approximately 4,246 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Denver, CO (DEN-Denver Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.)?
Select the "Business class" and "First class" filters when looking for DEN to CUZ flights on Expedia. This is the easiest way to compare prices, routes and flight times for your trip.
How do I earn miles on a Denver, CO (DEN-Denver Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.) flight with Expedia?
It's easy to earn miles on a Denver, CO (DEN-Denver Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Cusco from Denver Intl. (DEN)?
If you're planning to travel to Cusco from Denver Intl. (DEN), you can fly typically into Alejandro Velasco Astete Intl. (CUZ) Some flights may connect through major hubs like Hartsfield-Jackson Atlanta Intl. (ATL), Miami Intl. (MIA), George Bush Intercontinental (IAH) before reaching Cusco. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Denver, CO (DEN-Denver Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.) at the last minute?
Typically, booking a last minute flight from Denver, CO (DEN-Denver Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Denver, CO (DEN-Denver Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.) flight and hotel package?
Securing a Denver, CO (DEN-Denver Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.) Cusco Vacation Packages is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Denver, CO (DEN-Denver Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.)?
If you booked your Denver, CO (DEN-Denver Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Denver Intl.
Destination airport
Alejandro Velasco Astete Intl.
Roundtrip price
$749
Distance
4245 mi

Book with confidence

Denver to Cusco Flights

The cheapest times to fly from Denver to Cusco

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Denver to Cusco are during the month of February. You can find some of the cheapest flights from Denver to Cusco with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Denver to Cusco

Sunday is one of the best days to book for cheap flights from Denver to Cusco: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Denver to Cusco

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Denver to Cusco in 2026. You can also book with separate airlines for your outbound and return journeys, from $394 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Denver to Cusco flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Denver to Cusco airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Denver to Cusco Flights

*Flight schedules are subject to change.

*Available to One Key members.

 

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