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$322 Cheap Flights from Chicago (ORD) to Cusco (CUZ)

View $322 flight on Sun, Nov 1, 2026Opens in a new window

Popular airlines from Chicago O'Hare Intl. Airport (ORD) to Alejandro Velasco Astete Intl. Airport (CUZ)

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Cheap Flights from Chicago to Cusco (ORD-CUZ)

Prices were available within the past 7 days and start at $322 for one-way flights and $695 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Air Canada
Sun, Nov 1 - Sat, Nov 7
ORD
Chicago
CUZ
Cusco
$695 Roundtrip, found 2 hours ago
$695
Roundtrip
found 2 hours ago
Select Air Canada flight, departing Sun, Nov 1 from Chicago to Cusco, returning Sat, Nov 7, priced at $695 found 2 hours ago
Air Canada
Sun, Nov 1 - Sun, Nov 8
ORD
Chicago
CUZ
Cusco
$712 Roundtrip, found 1 hour ago
$712
Roundtrip
found 1 hour ago
Select Air Canada flight, departing Sun, Nov 1 from Chicago to Cusco, returning Sun, Nov 8, priced at $712 found 1 hour ago
Air Canada
Sun, Oct 25 - Fri, Oct 30
ORD
Chicago
CUZ
Cusco
$715 Roundtrip, found 2 hours ago
$715
Roundtrip
found 2 hours ago
Select Air Canada flight, departing Sun, Oct 25 from Chicago to Cusco, returning Fri, Oct 30, priced at $715 found 2 hours ago
Air Canada
Sat, Nov 7 - Sat, Nov 14
ORD
Chicago
CUZ
Cusco
$717 Roundtrip, found 5 hours ago
$717
Roundtrip
found 5 hours ago
Select Air Canada flight, departing Sat, Nov 7 from Chicago to Cusco, returning Sat, Nov 14, priced at $717 found 5 hours ago
Air Canada
Thu, Nov 12 - Sun, Nov 22
ORD
Chicago
CUZ
Cusco
$717 Roundtrip, found 21 hours ago
$717
Roundtrip
found 21 hours ago
Select Air Canada flight, departing Thu, Nov 12 from Chicago to Cusco, returning Sun, Nov 22, priced at $717 found 21 hours ago
Air Canada
Sat, Nov 7 - Sat, Nov 14
ORD
Chicago
CUZ
Cusco
$720 Roundtrip, found 5 hours ago
$720
Roundtrip
found 5 hours ago
Select Air Canada flight, departing Sat, Nov 7 from Chicago to Cusco, returning Sat, Nov 14, priced at $720 found 5 hours ago
American Airlines
Mon, Aug 24 - Sun, Aug 30
ORD
Chicago
CUZ
Cusco
$1,010 Roundtrip, found 1 hour ago
$1,010
Roundtrip
found 1 hour ago
Select American Airlines flight, departing Mon, Aug 24 from Chicago to Cusco, returning Sun, Aug 30, priced at $1,010 found 1 hour ago
Delta
Tue, Aug 18 - Tue, Aug 25
ORD
Chicago
CUZ
Cusco
$1,010 Roundtrip, found 1 hour ago
$1,010
Roundtrip
found 1 hour ago
Select Delta flight, departing Tue, Aug 18 from Chicago to Cusco, returning Tue, Aug 25, priced at $1,010 found 1 hour ago
avianca
Thu, Oct 8 - Wed, Oct 21
ORD
Chicago
CUZ
Cusco
$1,011 Roundtrip, just found
$1,011
Roundtrip
just found
Select avianca flight, departing Thu, Oct 8 from Chicago to Cusco, returning Wed, Oct 21, priced at $1,011 just found
LATAM Airlines Group
Tue, Oct 6 - Sat, Oct 10
ORD
Chicago
CUZ
Cusco
$1,041 Roundtrip, just found
$1,041
Roundtrip
just found
Select LATAM Airlines Group flight, departing Tue, Oct 6 from Chicago to Cusco, returning Sat, Oct 10, priced at $1,041 just found

Alternative airports near Cusco

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Alejandro Velasco Astete Intl. CUZ. Cheapest and Closest option available. Average driving time to city center is 4 minutes. Flights from $1,048
CUZ
Alejandro Velasco Astete Intl.
CheapestClosest
Average driving time to city center4 min
Flights from $1,048

Frequently asked questions

How much does a flight from Chicago, IL (ORD-O'Hare Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.) cost?
You can find cheap one-way flights from $322 and cheap return flights from $695 Chicago, IL (ORD-O'Hare Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.) with Expedia. One-way flights usually range from $436 to $2536, and return flights typically cost between $841 and $3229. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Chicago, IL (ORD-O'Hare Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Chicago, IL (ORD-O'Hare Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.)?
The cheapest month to fly from ORD to CUZ is November when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you're able to. Use the calendar view in your search to see which months have low fares on this route.
Which airlines fly direct from Chicago, IL (ORD-O'Hare Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.)?
Enter ORD to CUZ and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Chicago, IL (ORD-O'Hare Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.)?
American Airlines is one of the cheapest airlines offering connecting flights from O'Hare Intl. (ORD) to Alejandro Velasco Astete Intl. (CUZ), with round-trip tickets starting from around $778 with a layover in Miami Intl. (MIA). Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.*Prices based on flights available on Expedia in the last year.
How do I find cheap flights from Chicago, IL (ORD-O'Hare Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.)?
To find a cheap flight from Chicago, IL (ORD-O'Hare Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Chicago, IL (ORD-O'Hare Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
What is the earliest flight from Chicago, IL (ORD-O'Hare Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.)?
The earliest flight from O'Hare Intl. (ORD) to Alejandro Velasco Astete Intl. (CUZ) typically departs at around 12:30 AM, operated by Aeromexico and LATAM Airlines Group. This flight is available in January, making it a great choice for early travelers looking to explore Cusco. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from Chicago, IL (ORD-O'Hare Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.)?
The most popular departure times for flights from Chicago O'Hare International Airport (ORD) to Cusco (CUZ) are in the late afternoon to early evening, from 3pm to 6pm. About 39% of passengers prefer this time window. Many major carriers, including Delta, American Airlines, and United Airlines, offer flights during this window. This timing works well because it allows you to arrive in Cusco with plenty of time to settle in before exploring.
How long does it take to fly from Chicago, IL (ORD-O'Hare Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.)?
A flight from ORD to CUZ with a layover takes around 12 hours, with the route covering approximately 3,968 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Chicago, IL (ORD-O'Hare Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.)?
Business class seats are offered on the ORD to CUZ route with Avianca.
How do I earn miles on a Chicago, IL (ORD-O'Hare Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.) flight with Expedia?
It's easy to earn miles on a Chicago, IL (ORD-O'Hare Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Cusco from O'Hare Intl. (ORD)?
From O'Hare Intl. (ORD), you can fly into Alejandro Velasco Astete Intl. (CUZ) to reach Cusco. Some flights may connect through major hubs like Hartsfield-Jackson Atlanta Intl. (ATL), Miami Intl. (MIA), George Bush Intercontinental (IAH) before reaching Cusco. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Chicago, IL (ORD-O'Hare Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.) at the last minute?
Typically, booking a last minute flight from Chicago, IL (ORD-O'Hare Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Chicago, IL (ORD-O'Hare Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.) flight and hotel package?
Securing a Chicago, IL (ORD-O'Hare Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.) Cusco Vacation Packages is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Chicago, IL (ORD-O'Hare Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.)?
If you booked your Chicago, IL (ORD-O'Hare Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
O'Hare Intl.
Destination airport
Alejandro Velasco Astete Intl.
Airlines serving
Aeromexico, Air Canada, American Airlines, Delta, LATAM Airlines Group, avianca
Roundtrip price
$694
Distance
3967 mi

Book with confidence

Chicago to Cusco Flights

The cheapest times to fly from Chicago to Cusco

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Chicago to Cusco are during the month of November. You can find some of the cheapest flights from Chicago to Cusco with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Chicago to Cusco

Sunday is one of the best days to book for cheap flights from Chicago to Cusco: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Chicago to Cusco

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Chicago to Cusco in 2026. You can also book with separate airlines for your outbound and return journeys, from $322 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Chicago to Cusco flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Chicago to Cusco airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Chicago to Cusco Flights

*Flight schedules are subject to change.

*Available to One Key members.

 

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