Machu Picchu, an ancient Incan city, nestled in a mountainous valley with terraced fields and steep cliffs.

$365 Cheap Flights from Chicago (ORD) to Cusco (CUZ)

View $365 flight on Wed, Nov 25, 2026Opens in a new window

Popular airlines from Chicago O'Hare Intl. Airport (ORD) to Alejandro Velasco Astete Intl. Airport (CUZ)

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Cheap Flights from Chicago to Cusco (ORD-CUZ)

Prices were available within the past 7 days and start at $365 for one-way flights and $755 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Air Canada
Thu, Nov 26 - Mon, Nov 30
ORD
Chicago
CUZ
Cusco
$755 Roundtrip, found 1 day ago
$755
Roundtrip
found 1 day ago
Select Air Canada flight, departing Thu, Nov 26 from Chicago to Cusco, returning Mon, Nov 30, priced at $755 found 1 day ago
Air Canada
Thu, Nov 26 - Mon, Nov 30
ORD
Chicago
CUZ
Cusco
$760 Roundtrip, found 1 day ago
$760
Roundtrip
found 1 day ago
Select Air Canada flight, departing Thu, Nov 26 from Chicago to Cusco, returning Mon, Nov 30, priced at $760 found 1 day ago
Air Canada
Tue, Dec 1 - Mon, Dec 14
ORD
Chicago
CUZ
Cusco
$761 Roundtrip, found 1 day ago
$761
Roundtrip
found 1 day ago
Select Air Canada flight, departing Tue, Dec 1 from Chicago to Cusco, returning Mon, Dec 14, priced at $761 found 1 day ago
Air Canada
Sat, Nov 21 - Sun, Nov 29
ORD
Chicago
CUZ
Cusco
$768 Roundtrip, found 2 hours ago
$768
Roundtrip
found 2 hours ago
Select Air Canada flight, departing Sat, Nov 21 from Chicago to Cusco, returning Sun, Nov 29, priced at $768 found 2 hours ago
Air Canada
Sun, Nov 1 - Sun, Nov 8
ORD
Chicago
CUZ
Cusco
$770 Roundtrip, found 11 hours ago
$770
Roundtrip
found 11 hours ago
Select Air Canada flight, departing Sun, Nov 1 from Chicago to Cusco, returning Sun, Nov 8, priced at $770 found 11 hours ago
Air Canada
Sun, Nov 15 - Sat, Nov 21
ORD
Chicago
CUZ
Cusco
$773 Roundtrip, found 1 day ago
$773
Roundtrip
found 1 day ago
Select Air Canada flight, departing Sun, Nov 15 from Chicago to Cusco, returning Sat, Nov 21, priced at $773 found 1 day ago
American Airlines
Thu, Feb 25 - Sat, Mar 6
ORD
Chicago
CUZ
Cusco
$940 Roundtrip, found 11 hours ago
$940
Roundtrip
found 11 hours ago
Select American Airlines flight, departing Thu, Feb 25 from Chicago to Cusco, returning Sat, Mar 6, priced at $940 found 11 hours ago
Delta
Tue, Aug 18 - Thu, Aug 27
ORD
Chicago
CUZ
Cusco
$940 Roundtrip, just found
$940
Roundtrip
just found
Select Delta flight, departing Tue, Aug 18 from Chicago to Cusco, returning Thu, Aug 27, priced at $940 just found
LATAM Airlines Group
Wed, Aug 26 - Wed, Sep 2
ORD
Chicago
CUZ
Cusco
$971 Roundtrip, just found
$971
Roundtrip
just found
Select LATAM Airlines Group flight, departing Wed, Aug 26 from Chicago to Cusco, returning Wed, Sep 2, priced at $971 just found
avianca
Sat, Sep 5 - Fri, Sep 18
ORD
Chicago
CUZ
Cusco
$1,011 Roundtrip, just found
$1,011
Roundtrip
just found
Select avianca flight, departing Sat, Sep 5 from Chicago to Cusco, returning Fri, Sep 18, priced at $1,011 just found

Alternative airports near Cusco

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Alejandro Velasco Astete Intl. CUZ. Cheapest and Closest option available. Average driving time to city center is 4 minutes. Flights from $940
CUZ
Alejandro Velasco Astete Intl.
CheapestClosest
Average driving time to city center4 min
Flights from $940

Find the cheapest month to fly from Chicago (ORD) to Cusco (CUZ)

November is typically the cheapest month to fly

From $697 - $1,093 per traveler.

What you need to know for your flight from O'Hare Intl. to Alejandro Velasco Astete Intl.

Chicago (ORD) to Cusco (CUZ) at a glance

Explore a variety of airlines offering flights from Chicago O'Hare International Airport (ORD) to Alejandro Velasco Astete International Airport (CUZ) on this international long-haul journey. Compare options from both full-service carriers and budget-friendly airlines to find the best itinerary that aligns with your travel plans, budget, and schedule as you prepare to discover Cusco's iconic landmarks and vibrant neighborhoods. Get ready for an unforgettable adventure!

  • Fastest flight duration: around 9h 30m in-flight, plus roughly 2h 30m layover with one stop
  • Route distance: roughly 4,000 miles (6,440 km)
  • Flights per week: around 9 departures on average
  • Typical fares (one-way): economy tickets often range from $280–$690, depending on seasonality and how far ahead you book

Flights from O'Hare International Airport (ORD) to Alejandro Velasco Astete International Airport (CUZ)

According to the latest traveler bookings, here are the top airlines favored for flights from Chicago to Cusco, particularly for multi-stop and one-stop journeys. Popular layover airports include Jorge Chávez International Airport (LIM) with an approximate 2h 30m layover, Hartsfield-Jackson Atlanta International Airport (ATL) at about 2h 15m, and Miami International Airport (MIA), also around 2h 15m. This variety allows you to explore different combinations of price, total travel time, and cabin class to create the ideal travel itinerary.

  • Avianca: This full-service airline provides a convenient one-stop option, with one-way fares generally falling between $280 and $910. It represents about 42% of flights on this route, featuring an in-flight duration of 9 hours and 30 minutes, and a total travel time of approximately 12 hours, including layover.
  • Delta: As a full-service airline offering multi-stop itineraries, Delta's one-way fares typically range from $375 to $690. It accounts for around 25% of departures along this route, with an in-flight time of 10 hours and 15 minutes, leading to a total journey time of about 15 hours and 15 minutes, including layovers.
  • LATAM Airlines Group: This full-service carrier provides multi-stop services with one-way fares usually between $340 and $715. LATAM holds a share of approximately 14% of departures on this route, featuring an in-flight duration of 10 hours and 15 minutes, with a total travel time of roughly 15 hours and 15 minutes, including layovers.
  • American Airlines: Operating as a full-service airline with multi-stop options, American Airlines offers one-way fares typically ranging from $365 to $755. It covers about 11% of departures on this route, with a flight time of 10 hours and 15 minutes, resulting in an overall journey time of around 15 hours and 15 minutes, inclusive of layovers.
  • United: A full-service carrier providing multi-stop services, United's one-way fares generally range from $295 to $455. Representing approximately 7% of departures on this route, travelers can expect 10 hours and 15 minutes of flight time, with a total travel duration of about 15 hours and 15 minutes, including layovers.

Travelers flying from Chicago to Cusco can opt for an upgrade to business class, as Avianca provides premium service on this route.

Best time to fly from Chicago (ORD) to Cusco (CUZ)

The most popular months for travelers flying from Chicago to Cusco are January, March, and May, when peak temperatures in Cusco reach up to 50.2°F in January. If you prefer quieter travel, consider February, the least busy and relatively cheaper time to visit with fewer crowds and temperatures around 50°F. For better deals, September usually offers the lowest average one-way fare around $404. Flight availability peaks in March and May, with approximately 10 flights per week, making it easier to find convenient departure times. November and December have the fewest flights, with approximately 7 flights per week.

  • Cheapest time to fly: September usually offers good deals with average one-way fare around $404, roughly 17% cheaper than the yearly average.
  • More budget-friendly months to fly: February and January typically offer average one-way fares of around $430.
  • Most flight options: March and May have the highest number of flights from Chicago to Cusco, with approximately 10 flights per week, giving you more flexibility in scheduling your trip.
calendar iconMonthtemperature iconTemperaturecrowd level iconDemandflights iconWeekly Flightsprice iconAverage one-way Fare
January50.2°F (10.1°C)High8$435
February50.0°F (10.0°C)Low9$425
March49.8°F (9.9°C)High10$459
April49.6°F (9.8°C)Average9$520
May48.6°F (9.2°C)High10$472
June47.7°F (8.7°C)Average8$521
July47.8°F (8.8°C)Average8$505
August49.5°F (9.7°C)Average9$563
September51.1°F (10.6°C)Average8$404
October52.2°F (11.2°C)Low9$587
November52.5°F (11.4°C)Low7$491
December51.1°F (10.6°C)Average7$513

*Average one-way fare is based on Expedia flight booking data from January 2025 to April 2026 for the specified route and travel class and may change depending on availability, dates, and demand.

Alternative route from Chicago (ORD) to Cusco (CUZ)

  • Chicago to Cusco (MDW-CUZ): Midway International Airport (MDW) is located approximately 16 miles from O'Hare International Airport (ORD).

How to find the best prices for flights from Chicago (ORD) to Cusco (CUZ)

Getting some of the best deals on flights from Chicago to Cusco is all about timing and flexibility. Here are some key tips to help you save:

  1. Best times to book and fly: cheaper fares are usually available when booking at least two months in advance, which coincides with when most travelers make their reservations. Afternoon departures, between 12 p.m. and 6 p.m., tend to be more affordable and are also popular. Additionally, flying on Wednesdays often provides lower prices, while Fridays are the busiest travel days.
  2. Set up price alerts: stay updated on price changes by using Expedia's Price Tracker. Receive alerts when fares drop for your selected route.
  3. Bundle and save: bundle your flight and hotel to save on Expedia, or unlock a hotel deal after booking your flight.* Find Cusco hotel and flight deals.
  4. Compare flight options: use Expedia's search tool to compare airlines, routes, direct vs. non-direct flights, and flight times. You can also sort by price to find the most affordable options.
  5. Stay flexible with dates: being open to different travel days can sometimes help you find better prices on flights and hotels.
  6. Think about luggage: nowadays, it's important to check the airline's baggage policies to find the best value. That may be paying for an additional carry-on bag or booking a ticket with checked luggage included. Either way, double-check your allowance before confirming your booking to avoid excess baggage fees at the airport.

*Members only. Savings vary and are not available on all bundles. Select hotels.

Arriving at Alejandro Velasco Astete International Airport from O'Hare International Airport

Cusco welcomes travelers from Chicago with a range of transport options based on price, convenience, and proximity. Here's how to reach Cusco efficiently:

  • Hotel transfer: Transfers offer a convenient way to reach your hotel in Cusco, with options including free hotel shuttles and private rides, which can be arranged in advance with your hotel.
  • Car rental: Renting a car from Alejandro Velasco Astete International Airport is a great option if you plan to explore and sightsee beyond the city. Browse cheap car rentals at Alejandro Velasco Astete International Airport on Expedia.
  • Taxi/ride-hailing: Taxis and ride-hailing services may be available from designated pickup areas outside the terminal, check locally on arrival.
  • Public transportation: From Alejandro Velasco Astete International Airport, several transport options are conveniently located within a short drive. Cusco Bus Station, a bus station, is about 1.6 miles away by car, while Cusco Wanchaq Station, a train station, is approximately 2.5 miles from the airport. Additionally, if you're headed to the water, Cusco Seaport, a seaport, is around 3.2 miles away by car.

Frequently asked questions

How much does a flight from Chicago, IL (ORD-O'Hare Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.) cost?
You can find cheap one-way flights from $365 and cheap return flights from $755 Chicago, IL (ORD-O'Hare Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.) with Expedia. One-way flights usually range from $436 to $2536, and return flights typically cost between $841 and $3229. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Chicago, IL (ORD-O'Hare Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Chicago, IL (ORD-O'Hare Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.)?
The cheapest month to fly from ORD to CUZ is November when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you're able to. Use the calendar view in your search to see which months have low fares on this route.
Which airlines fly direct from Chicago, IL (ORD-O'Hare Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.)?
Enter ORD to CUZ and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Chicago, IL (ORD-O'Hare Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.)?
American Airlines is one of the cheapest airlines offering connecting flights from O'Hare Intl. (ORD) to Alejandro Velasco Astete Intl. (CUZ), with round-trip tickets starting from around $778 with a layover in Miami Intl. (MIA). Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.*Prices based on flights available on Expedia in the last year.
How do I find cheap flights from Chicago, IL (ORD-O'Hare Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.)?
To find a cheap flight from Chicago, IL (ORD-O'Hare Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Chicago, IL (ORD-O'Hare Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
What is the earliest flight from Chicago, IL (ORD-O'Hare Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.)?
The earliest flight from O'Hare Intl. (ORD) to Alejandro Velasco Astete Intl. (CUZ) typically departs at around 12:30 AM, operated by Aeromexico and LATAM Airlines Group. This flight is available in January, making it a great choice for early travelers looking to explore Cusco. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from Chicago, IL (ORD-O'Hare Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.)?
The most popular departure times for flights from Chicago O'Hare International Airport (ORD) to Cusco (CUZ) are in the late afternoon to early evening, from 3pm to 6pm. About 39% of passengers prefer this time window. Many major carriers, including Delta, American Airlines, and United Airlines, offer flights during this window. This timing works well because it allows you to arrive in Cusco with plenty of time to settle in before exploring.
How long does it take to fly from Chicago, IL (ORD-O'Hare Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.)?
A flight from ORD to CUZ with a layover takes around 12 hours, with the route covering approximately 3,968 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Chicago, IL (ORD-O'Hare Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.)?
Business class seats are offered on the ORD to CUZ route with Avianca.
How do I earn miles on a Chicago, IL (ORD-O'Hare Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.) flight with Expedia?
It's easy to earn miles on a Chicago, IL (ORD-O'Hare Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Cusco from O'Hare Intl. (ORD)?
From O'Hare Intl. (ORD), you can fly into Alejandro Velasco Astete Intl. (CUZ) to reach Cusco. Some flights may connect through major hubs like Hartsfield-Jackson Atlanta Intl. (ATL), Miami Intl. (MIA), George Bush Intercontinental (IAH) before reaching Cusco. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Chicago, IL (ORD-O'Hare Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.) at the last minute?
Typically, booking a last minute flight from Chicago, IL (ORD-O'Hare Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Chicago, IL (ORD-O'Hare Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.) flight and hotel package?
Securing a Chicago, IL (ORD-O'Hare Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.) Cusco Vacation Packages is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Chicago, IL (ORD-O'Hare Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.)?
If you booked your Chicago, IL (ORD-O'Hare Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
O'Hare Intl.
Destination airport
Alejandro Velasco Astete Intl.
Airlines serving
Aeromexico, Air Canada, American Airlines, Delta, LATAM Airlines Group, avianca
Roundtrip price
$755
Distance
3967 mi

Book with confidence

Chicago to Cusco Flights

The cheapest times to fly from Chicago to Cusco

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Chicago to Cusco are during the month of November. You can find some of the cheapest flights from Chicago to Cusco with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Chicago to Cusco

Sunday is one of the best days to book for cheap flights from Chicago to Cusco: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Chicago to Cusco

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Chicago to Cusco in 2026. You can also book with separate airlines for your outbound and return journeys, from $365 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Chicago to Cusco flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Chicago to Cusco airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Chicago to Cusco Flights

*Flight schedules are subject to change.

*Available to One Key members.

 

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