$327 Cheap Flights from Denver (DEN) to Roanoke (ROA)

Denver (DEN) to Roanoke (ROA) at a glance

Travel from Denver (DEN) to Roanoke (ROA) with a selection of airlines on this domestic short-haul route. Explore various options for flights from Denver International Airport to Roanoke Regional Airport, comparing itineraries from full-service carriers that suit your budget and schedule. Whether you’re visiting Roanoke’s iconic attractions or charming neighborhoods, you’ll find the flight prices that align with your travel plans.

• Fastest flight duration: around 4h 30m in-flight, plus roughly 1h 15m layover with one stop
• Route distance: roughly 1,300 miles (2,090 km)
• Flights per week: around 11 departures on average
• Typical fares (one-way): economy tickets often range from $125–$470, depending on seasonality and how far ahead you book

Flights from Denver International Airport (DEN) to Roanoke Regional Airport (ROA)

Based on the latest traveler bookings, here are the top airlines flying from Denver to Roanoke, commonly selected for their one-stop services. Popular layover options include Charlotte-Douglas International Airport (CLT) with an approximately 1 hour and 15 minute layover, Washington Dulles International Airport (IAD) at about 1 hour and 30 minutes, and Hartsfield-Jackson Atlanta International Airport (ATL) with a layover of roughly 1 hour and 15 minutes. These choices allow you to balance price, total travel time, and cabin class for the ideal itinerary.

• American Airlines: This full-service airline operates one-stop flights, with one-way ticket prices generally between $125 and $440. It makes up about 51% of the departures on this route, featuring an in-flight duration of 4 hours and 30 minutes and a total travel time of approximately 6 hours, including the layover.
• United: Offering one-stop service, United is a full-service carrier with one-way fares usually ranging from $125 to $485. It represents around 28% of the flights on this route, with an in-flight time of 4 hours and 30 minutes and an overall journey duration of roughly 6 hours, including layover time.
• Delta: As a full-service airline providing one-stop service, Delta's one-way fares typically fall between $125 and $490. It accounts for about 20% of the departures along this route, with a flight duration of 4 hours and 30 minutes and a total travel time of about 6 hours, factoring in the layover.

Travelers flying from Denver to Roanoke have the option to upgrade their flight, as Delta provides premium economy class service on this route.

Best time to fly from Denver (DEN) to Roanoke (ROA)

The most popular months for travelers flying from Denver to Roanoke are March, April, and May, when peak temperatures in Roanoke reach up to 63.3°F in May. If you prefer quieter travel, consider February, the least busy and relatively cheaper time to visit with fewer crowds and temperatures around 37.8°F. For better deals, August usually offers the lowest average one-way fare around $200. Flight availability peaks in May, September, November, and December, with approximately 12 flights per week, making it easier to find convenient departure times. January has the fewest flights, with approximately 9 flights per week.

• Cheapest time to fly: August usually offers good deals with average one-way fare around $200, roughly 18% cheaper than the yearly average.
• Another budget-friendly time to fly: September typically offers an average one-way fare of around $219.
• Most flight options: May, September, November, and December have the highest number of flights from Denver to Roanoke, with approximately 12 flights per week, giving you more flexibility in scheduling your trip.

*Average one-way fare is based on Expedia flight booking data from January 2025 to April 2026 for the specified route and travel class and may change depending on availability, dates, and demand.

Alternative routes from Denver (DEN) to Roanoke (ROA)

• Colorado Springs to Roanoke (COS-ROA): Located approximately 73 miles from Denver International Airport (DEN), Colorado Springs Airport (COS) serves this route. One-way economy tickets generally fall within the range of $135 to $515, influenced by the time of year and how far in advance you book. Flights typically feature both one-stop and multi-stop options, with common layover points at O'Hare International Airport (ORD) and Hartsfield-Jackson Atlanta International Airport (ATL). Major airlines operating on this route include United and Delta, and first-class service is also available.
• Denver to Lynchburg (DEN-LYH): Lynchburg Regional Airport (LYH) is about 43 miles from Roanoke Regional Airport (ROA). One-way economy fares on this route usually span from $185 to $455, depending on seasonality and booking timing. The flights are generally one-stop, featuring popular layovers at Charlotte-Douglas International Airport (CLT) and O'Hare International Airport (ORD). Leading airlines for this route consist of American Airlines and United.
• Denver to Greensboro (DEN-GSO): Piedmont Triad International Airport (GSO) is roughly 84 miles distant from Roanoke Regional Airport (ROA). One-way economy prices on this route typically range from $125 to $520, influenced by the season and advance booking. Travelers can find both one-stop and non-stop options, with frequent layovers at Charlotte-Douglas International Airport (CLT) and Hartsfield-Jackson Atlanta International Airport (ATL). United and American Airlines are the primary carriers for this route, and first-class service is offered as well.

How to find the best prices for flights from Denver (DEN) to Roanoke (ROA)

Getting some of the best deals on flights from Denver to Roanoke is all about timing and flexibility. Here are some key tips to help you save:

1. Best times to book and fly: cheaper fares are usually available when booking 2-8 weeks in advance, which coincides with when most travelers make their reservations. Early morning departures (12 am-5 am) often offer lower prices, while morning flights (5 am-12 pm) are more popular. Additionally, flying on Wednesday typically results in cheaper fares, although Thursday is the busiest travel day.
2. Set up price alerts: stay updated on price changes by using Expedia's Price Tracker. Receive alerts when fares drop for your selected route.
3. Bundle and save: bundle your flight and hotel to save on Expedia, or unlock a hotel deal after booking your flight.* Find Roanoke hotel and flight deals.
4. Compare flight options: use Expedia's search tool to compare airlines, routes, direct vs. non-direct flights, and flight times. You can also sort by price to find the most affordable options.
5. Stay flexible with dates: being open to different travel days can sometimes help you find better prices on flights and hotels.
6. Think about luggage: nowadays, it's important to check the airline's baggage policies to find the best value. That may be paying for an additional carry-on bag or booking a ticket with checked luggage included. Either way, double-check your allowance before confirming your booking to avoid excess baggage fees at the airport.

*Members only. Savings vary and are not available on all bundles. Select hotels.

Arriving at Roanoke Regional Airport from Denver International Airport

Roanoke welcomes travelers from Denver with a range of transport options based on price, convenience, and proximity. Here's how to reach Roanoke efficiently:

• Hotel transfer: Transfers offer a convenient way to reach your hotel in Roanoke, with options including free hotel shuttles and private rides, which can be arranged in advance with your hotel.
• Car rental: Renting a car from Roanoke Regional Airport is a great option if you plan to explore and sightsee beyond the city. Browse cheap car rentals at Roanoke Regional Airport on Expedia.
• Taxi/ride-hailing: Taxis and ride-hailing services may be available from designated pickup areas outside the terminal, check locally on arrival.
• Public transportation: From Roanoke Regional Airport, Roanoke Station, a train station, is located about 5.7 miles away by car.

Denver to Roanoke Flights

The cheapest times to fly from Denver to Roanoke

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Denver to Roanoke are during the month of September. You can find some of the cheapest flights from Denver to Roanoke with Expedia's search tool and vast selection of airlines.

The best time to book a flight from Denver to Roanoke

Sunday is one of the best days to book for cheap flights from Denver to Roanoke: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

How to find cheap round-trip tickets from Denver to Roanoke

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Denver to Roanoke in 2026. You can also book with separate airlines for your outbound and return journeys, from $327 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Denver to Roanoke flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

You could also save big by booking one of Expedia's vacation packages. Bundling together your Denver to Roanoke airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

*Terms apply.

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.