Skip to main content
Beginning of main content

Cheap Flights from Des Moines to Key West $373.85

Search over 321,000 hotels worldwide and 400 airlines worldwide.
Secure incredible value with Expedia’s Price Pledge
No Expedia cancellation fee to change or cancel almost any hotel reservation.

Cheapest Flights from Des Moines to Key West (DSM to EYW)

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Interesting Facts About Flights from Des Moines to Key West (DSM to EYW)

Question : Interested in traveling in the next 30 days and want to get the lowest fare?
Answer : December 14th offers bookings (as of December 5th) that are 45% below the average price for this route. Saving on booking fees means you'll have more cash in your pocket for the trip.

Question : How many days should you spend in Key West if you're flying in from Des Moines?
Answer : Of course you're not most people, but if you were, you'd stay roughly six days.

Question : Will you do what it takes to get the absolute lowest-cost flight?
Answer : In December, Tuesday is your cheapest day to fly. Having flexibility in your travel plans means you can save, so be sure to plan ahead when possible.

Question : Do prices fluctuate more for this route than others?
Answer : Prices for this trip tend to change a lot more than others. The further out you book a route, the more likely you are to save.