The Vatican's St. Peter's Square with the Vatican Museums and the obelisk in the background.

$356 Cheap Flights from Des Moines (DSM) to Rome (FCO)

View $356 flight on Mon, Mar 8, 2027Opens in a new window

Popular airlines from Des Moines International Airport (DSM) to Fiumicino - Leonardo da Vinci Intl. Airport (FCO)

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Cheap Flights from Des Moines to Rome (DSM-FCO)

Prices were available within the past 7 days and start at $356 for one-way flights and $596 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Wed, Oct 28 - Thu, Nov 5
DSM
Des Moines
FCO
Rome
$596 Roundtrip, found 3 hours ago
$596
Roundtrip
found 3 hours ago
Select Delta flight, departing Wed, Oct 28 from Des Moines to Rome, returning Thu, Nov 5, priced at $596 found 3 hours ago
Delta
Wed, Oct 28 - Fri, Nov 6
DSM
Des Moines
FCO
Rome
$601 Roundtrip, found 22 hours ago
$601
Roundtrip
found 22 hours ago
Select Delta flight, departing Wed, Oct 28 from Des Moines to Rome, returning Fri, Nov 6, priced at $601 found 22 hours ago
Delta
Wed, Jan 20 - Wed, Jan 27
DSM
Des Moines
FCO
Rome
$602 Roundtrip, found 1 day ago
$602
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, Jan 20 from Des Moines to Rome, returning Wed, Jan 27, priced at $602 found 1 day ago
Delta
Wed, Jan 20 - Wed, Jan 27
DSM
Des Moines
FCO
Rome
$606 Roundtrip, found 1 day ago
$606
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, Jan 20 from Des Moines to Rome, returning Wed, Jan 27, priced at $606 found 1 day ago
Delta
Wed, Oct 28 - Fri, Nov 6
DSM
Des Moines
FCO
Rome
$616 Roundtrip, found 22 hours ago
$616
Roundtrip
found 22 hours ago
Select Delta flight, departing Wed, Oct 28 from Des Moines to Rome, returning Fri, Nov 6, priced at $616 found 22 hours ago
Delta
Wed, Jan 20 - Wed, Jan 27
DSM
Des Moines
FCO
Rome
$621 Roundtrip, found 1 day ago
$621
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, Jan 20 from Des Moines to Rome, returning Wed, Jan 27, priced at $621 found 1 day ago
KLM
Wed, Dec 2 - Wed, Dec 9
DSM
Des Moines
FCO
Rome
$643 Roundtrip, found 17 hours ago
$643
Roundtrip
found 17 hours ago
Select KLM flight, departing Wed, Dec 2 from Des Moines to Rome, returning Wed, Dec 9, priced at $643 found 17 hours ago
Air France
Wed, Jan 20 - Wed, Jan 27
DSM
Des Moines
FCO
Rome
$649 Roundtrip, found 1 day ago
$649
Roundtrip
found 1 day ago
Select Air France flight, departing Wed, Jan 20 from Des Moines to Rome, returning Wed, Jan 27, priced at $649 found 1 day ago
United
Wed, Nov 25 - Fri, Dec 4
DSM
Des Moines
FCO
Rome
$726 Roundtrip, found 3 hours ago
$726
Roundtrip
found 3 hours ago
Select United flight, departing Wed, Nov 25 from Des Moines to Rome, returning Fri, Dec 4, priced at $726 found 3 hours ago
Air Canada
Sun, Oct 25 - Tue, Nov 10
DSM
Des Moines
FCO
Rome
$731 Roundtrip, just found
$731
Roundtrip
just found
Select Air Canada flight, departing Sun, Oct 25 from Des Moines to Rome, returning Tue, Nov 10, priced at $731 just found

Alternative airports near Rome

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Fiumicino - Leonardo da Vinci Intl. FCO. Cheapest option available. Average driving time to city center is 26 minutes. Flights from $1,409
FCO
Fiumicino - Leonardo da Vinci Intl.
Cheapest
Average driving time to city center26 min
Flights from $1,409

Find the cheapest month to fly from Des Moines (DSM) to Rome (FCO)

February is typically the cheapest month to fly

From $745 - $882 per traveler.

What you need to know for your flight from Des Moines Intl. to Fiumicino - Leonardo da Vinci Intl.

Des Moines (DSM) to Rome (FCO) at a glance

Embark on an international long-haul journey from Des Moines (DSM) to Rome (FCO) with a range of airlines offering various routes. Explore options from full-service carriers to discover the itinerary that aligns with your budget, schedule, and travel plans while you take in the iconic sights and neighborhoods of Rome. Get all the essential details for flights departing from Des Moines International Airport (DSM) to Fiumicino - Leonardo da Vinci International Airport (FCO).

  • Fastest flight duration: around 10h 45m in-flight, plus roughly 2h 45m layover with one stop
  • Route distance: roughly 5,100 miles (8,210 km)
  • Flights per week: around 7 departures on average
  • Typical fares (one-way): economy tickets often range from $260–$880, depending on seasonality and how far ahead you book

Flights from Des Moines International Airport (DSM) to Fiumicino - Leonardo da Vinci International Airport (FCO)

Based on the latest traveler bookings, here are the top airlines favored by travelers flying from Des Moines to Rome, typically for one-stop and multi-stop flights. Popular layover options include O'Hare International Airport (ORD) with about a 2 hour and 45 minute layover, Hartsfield-Jackson Atlanta International Airport (ATL) with roughly a 2-hour layover, and Detroit Metropolitan Wayne County Airport (DTW) with approximately a 4-hour layover. This variety allows you to customize your itinerary by balancing price, total travel time, and cabin class.

  • Delta: As a prominent full-service airline, Delta provides both one-stop and multi-stop options. One-way ticket prices generally fall between $260 and $1195. This carrier accounts for about 30% of departures on this route, featuring an average in-flight duration of 10 hours and 45 minutes, leading to a total travel time of approximately 13 hours and 45 minutes.
  • American Airlines: Another leading full-service option, American Airlines offers one-stop and multi-stop flights, with one-way fares typically ranging from $435 to $860. This airline represents roughly 23% of departures on the route, with an in-flight time of 10 hours and 45 minutes, culminating in a total journey time of around 13 hours and 45 minutes.
  • United: United Airlines, a full-service carrier, provides one-stop and multi-stop service as well. Their one-way fares are usually between $275 and $720. They account for approximately 23% of departures on this route, with a standard in-flight duration of 10 hours and 45 minutes, leading to a total travel time close to 13 hours and 45 minutes.
  • KLM: Operating as a full-service airline, KLM primarily offers one-stop flights. Ticket prices for one-way journeys typically range from $430 to $875, contributing to about 14% of departures on this route. Passengers can expect an in-flight time of 10 hours and 45 minutes, with a total travel duration of roughly 13 hours and 45 minutes, including layovers.

Alternative route from Des Moines (DSM) to Rome (FCO)

  • Des Moines to Perugia San Francesco d'Assisi – Umbria Intl. Airport (DSM-PEG): Perugia San Francesco d'Assisi – Umbria International Airport (PEG) is located approximately 91 miles from Fiumicino - Leonardo da Vinci International Airport (FCO).

How to find the best prices for flights from Des Moines (DSM) to Rome (FCO)

Getting some of the best deals on flights from Des Moines to Rome is all about timing and flexibility. Here are some key tips to help you save:

  1. Best times to book and fly: cheaper fares are usually found when booking 2-8 weeks in advance, although most travelers tend to book at least 2 months ahead. Morning departures between 5 a.m. and 12 p.m. often offer lower prices and are the most popular flight times, while flying on Tuesday generally provides the best deals, despite Friday being the most favored travel day.
  2. Set up price alerts: stay updated on price changes by using Expedia's Price Tracker. Receive alerts when fares drop for your selected route.
  3. Bundle and save: bundle your flight and hotel to save on Expedia, or unlock a hotel deal after booking your flight.*
  4. Compare flight options: use Expedia's search tool to compare airlines, routes, direct vs. non-direct flights, and flight times. You can also sort by price to find the most affordable options.
  5. Stay flexible with dates: being open to different travel days can sometimes help you find better prices on flights and hotels.
  6. Think about luggage: nowadays, it's important to check the airline's baggage policies to find the best value. That may be paying for an additional carry-on bag or booking a ticket with checked luggage included. Either way, double-check your allowance before confirming your booking to avoid excess baggage fees at the airport.

*Members only. Savings vary and are not available on all bundles. Select hotels.

Arriving at Fiumicino - Leonardo da Vinci International Airport from Des Moines International Airport

Rome welcomes travelers from Des Moines with a range of transport options based on price, convenience, and proximity. Rome city center is approximately a 25-minute drive (covering about 19 miles) from Fiumicino - Leonardo da Vinci International Airport, depending on traffic. Here's how to reach Rome efficiently:

  • Hotel transfer: Transfers offer a convenient way to reach your hotel in Rome, with private rides that can be arranged in advance.
  • Car rental: Renting a car from Fiumicino - Leonardo da Vinci International Airport is a great option if you plan to explore and sightsee beyond the city. Browse cheap car rentals at Fiumicino - Leonardo da Vinci International Airport on Expedia.
  • Taxi/ride-hailing: Taxis and ride-hailing services may be available from designated pickup areas outside the terminal, check locally on arrival.
  • Public transportation: From Fiumicino - Leonardo da Vinci International Airport, several transport options are conveniently located nearby. Fiumicino Airport Station, a train station, is about 0.2 miles from the airport and easily accessible on foot, while Rome-da Vinci/Fiumicino Seaport, a seaport, is approximately 0.4 miles away by car. Additionally, Stella Polare Station, a metro station, is located about 5.8 miles from the airport, also reachable by car.

Frequently asked questions

How much does a flight from Des Moines, IA (DSM-Des Moines Intl.) to Rome (FCO-Fiumicino - Leonardo da Vinci Intl.) cost?
You can find cheap one-way flights from $356 and cheap return flights from $596 Des Moines, IA (DSM-Des Moines Intl.) to Rome (FCO-Fiumicino - Leonardo da Vinci Intl.) with Expedia. One-way flights typically cost between $602 and $3379, and return flights often range between $801 and $4377. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Des Moines, IA (DSM-Des Moines Intl.) to Rome (FCO-Fiumicino - Leonardo da Vinci Intl.) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Des Moines, IA (DSM-Des Moines Intl.) to Rome (FCO-Fiumicino - Leonardo da Vinci Intl.)?
November is the cheapest month to fly from Des Moines (DSM) to Rome (FCO), with average round-trip fares around $720. This price is about 28% lower than the average throughout the year, as travel demand tends to drop after the summer. Other affordable months to consider are January and May.*Averages based on flights available on Expedia in the last year.
Which airlines fly direct from Des Moines, IA (DSM-Des Moines Intl.) to Rome (FCO-Fiumicino - Leonardo da Vinci Intl.)?
Enter DSM to FCO and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Des Moines, IA (DSM-Des Moines Intl.) to Rome (FCO-Fiumicino - Leonardo da Vinci Intl.)?
Virgin Atlantic is one of the cheapest airlines offering connecting flights from Des Moines, IA (DSM) to Rome (FCO), with round-trip tickets starting from around $1,090 with a layover in Hartsfield-Jackson Atlanta Intl. (ATL). Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.*Prices based on flights available on Expedia in the last year.
How do I find cheap flights from Des Moines, IA (DSM-Des Moines Intl.) to Rome (FCO-Fiumicino - Leonardo da Vinci Intl.)?
To find a cheap flight from Des Moines, IA (DSM-Des Moines Intl.) to Rome (FCO-Fiumicino - Leonardo da Vinci Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Des Moines, IA (DSM-Des Moines Intl.) to Rome (FCO-Fiumicino - Leonardo da Vinci Intl.)?
The best time to fly from Des Moines (DSM) to Rome (FCO) is in November or January. November features an average price of about $720, making it a reasonable choice for travelers. January is also a popular month, providing good flight options. These months offer a nice balance of affordability and enjoyable travel conditions.*Prices based on flights available on Expedia in the last year.
What is the earliest flight from Des Moines, IA (DSM-Des Moines Intl.) to Rome (FCO-Fiumicino - Leonardo da Vinci Intl.)?
The earliest flight from Des Moines International Airport (DSM) to Fiumicino - Leonardo da Vinci International Airport (FCO) usually departs at 5:00 AM. This seasonal service operates in April, June, July, August, and November, giving you a head start on your adventures in Rome. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from Des Moines, IA (DSM-Des Moines Intl.) to Rome (FCO-Fiumicino - Leonardo da Vinci Intl.)?
The most popular departure times for flights from Des Moines (DSM) to Rome (FCO) are from noon to 3pm. About 31% of passengers prefer this time window. Many major carriers, including American Airlines and British Airways, offer flights during this window. This timing is favored as it allows you to maximize your morning before traveling.
How long does it take to fly from Des Moines, IA (DSM-Des Moines Intl.) to Rome (FCO-Fiumicino - Leonardo da Vinci Intl.)?
Flights from DSM to FCO with one stop typically take around 13 hours 30 minutes, covering approximately 5,058 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Des Moines, IA (DSM-Des Moines Intl.) to Rome (FCO-Fiumicino - Leonardo da Vinci Intl.)?
Business class is available on flights from DSM to FCO. Airlines that offer business class service on this route include:

  • United Airlines
  • Delta Air Lines
  • American Airlines

How do I earn miles on a Des Moines, IA (DSM-Des Moines Intl.) to Rome (FCO-Fiumicino - Leonardo da Vinci Intl.) flight with Expedia?
It's easy to earn miles on a Des Moines, IA (DSM-Des Moines Intl.) to Rome (FCO-Fiumicino - Leonardo da Vinci Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Rome from Des Moines Intl. (DSM)?
If you're planning to travel to Rome from Des Moines Intl. (DSM), you can fly into Fiumicino - Leonardo da Vinci Intl. (FCO) Some flights may connect through major hubs like O'Hare Intl. (ORD), Detroit Metropolitan Wayne County (DTW), Hartsfield-Jackson Atlanta Intl. (ATL) before reaching Rome. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Des Moines, IA (DSM-Des Moines Intl.) to Rome (FCO-Fiumicino - Leonardo da Vinci Intl.) at the last minute?
Typically, booking a last minute flight from Des Moines, IA (DSM-Des Moines Intl.) to Rome (FCO-Fiumicino - Leonardo da Vinci Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Des Moines, IA (DSM-Des Moines Intl.) to Rome (FCO-Fiumicino - Leonardo da Vinci Intl.) flight and hotel package?
Securing a Des Moines, IA (DSM-Des Moines Intl.) to Rome (FCO-Fiumicino - Leonardo da Vinci Intl.) Rome Vacation Packages is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Des Moines, IA (DSM-Des Moines Intl.) to Rome (FCO-Fiumicino - Leonardo da Vinci Intl.)?
If you booked your Des Moines, IA (DSM-Des Moines Intl.) to Rome (FCO-Fiumicino - Leonardo da Vinci Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Des Moines Intl.
Destination airport
Fiumicino - Leonardo da Vinci Intl.
Airlines serving
Aer Lingus, Air Canada, Air France, American Airlines, British Airways, Delta, Finnair, Iberia, KLM, Lufthansa, Scandinavian Airlines, United
Roundtrip price
$596
Distance
5057 mi

Book with confidence

Des Moines to Rome Flights

The cheapest times to fly from Des Moines to Rome

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Des Moines to Rome are during the month of October. You can find some of the cheapest flights from Des Moines to Rome with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Des Moines to Rome

Sunday is one of the best days to book for cheap flights from Des Moines to Rome: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Des Moines to Rome

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Des Moines to Rome in 2026. You can also book with separate airlines for your outbound and return journeys, from $356 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Des Moines to Rome flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Des Moines to Rome airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Des Moines to Rome Flights

*Flight schedules are subject to change.

*Available to One Key members.

 

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