$395 Cheap Flights from Des Moines (DSM) to Rome (FCO)

View $395 flight on Wed, Dec 3, 2025Opens in a new window

Popular airlines from Des Moines International Airport (DSM) to Fiumicino - Leonardo da Vinci Intl. Airport (FCO)

Cheap Flights from Des Moines to Rome (DSM-FCO)

Prices were available within the past 7 days and start at $395 for one-way flights and $471 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Air Canada
Mon, Jan 19 - Mon, Jan 26
DSM
Des Moines
FCO
Rome
$471 Roundtrip, found 1 day ago
$471
Roundtrip
found 1 day ago
Select Air Canada flight, departing Mon, Jan 19 from Des Moines to Rome, returning Mon, Jan 26, priced at $471 found 1 day ago
Air Canada
Sat, Jan 17 - Sun, Jan 25
DSM
Des Moines
FCO
Rome
$477 Roundtrip, found 1 day ago
$477
Roundtrip
found 1 day ago
Select Air Canada flight, departing Sat, Jan 17 from Des Moines to Rome, returning Sun, Jan 25, priced at $477 found 1 day ago
Air Canada
Thu, Dec 4 - Wed, Dec 17
DSM
Des Moines
FCO
Rome
$483 Roundtrip, found 3 hours ago
$483
Roundtrip
found 3 hours ago
Select Air Canada flight, departing Thu, Dec 4 from Des Moines to Rome, returning Wed, Dec 17, priced at $483 found 3 hours ago
Air Canada
Mon, Jan 19 - Mon, Jan 26
DSM
Des Moines
FCO
Rome
$483 Roundtrip, found 1 day ago
$483
Roundtrip
found 1 day ago
Select Air Canada flight, departing Mon, Jan 19 from Des Moines to Rome, returning Mon, Jan 26, priced at $483 found 1 day ago
Air Canada
Thu, Dec 4 - Wed, Dec 17
DSM
Des Moines
FCO
Rome
$489 Roundtrip, found 3 hours ago
$489
Roundtrip
found 3 hours ago
Select Air Canada flight, departing Thu, Dec 4 from Des Moines to Rome, returning Wed, Dec 17, priced at $489 found 3 hours ago
Lufthansa
Mon, Jan 19 - Mon, Jan 26
DSM
Des Moines
FCO
Rome
$491 Roundtrip, found 1 day ago
$491
Roundtrip
found 1 day ago
Select Lufthansa flight, departing Mon, Jan 19 from Des Moines to Rome, returning Mon, Jan 26, priced at $491 found 1 day ago
Air Canada
Mon, Jan 19 - Mon, Jan 26
DSM
Des Moines
FCO
Rome
$493 Roundtrip, found 1 day ago
$493
Roundtrip
found 1 day ago
Select Air Canada flight, departing Mon, Jan 19 from Des Moines to Rome, returning Mon, Jan 26, priced at $493 found 1 day ago
United
Tue, Jan 13 - Fri, Feb 13
DSM
Des Moines
FCO
Rome
$502 Roundtrip, found 7 hours ago
$502
Roundtrip
found 7 hours ago
Select United flight, departing Tue, Jan 13 from Des Moines to Rome, returning Fri, Feb 13, priced at $502 found 7 hours ago
American Airlines
Fri, Dec 5 - Mon, Dec 8
DSM
Des Moines
FCO
Rome
$502 Roundtrip, found 2 days ago
$502
Roundtrip
found 2 days ago
Select American Airlines flight, departing Fri, Dec 5 from Des Moines to Rome, returning Mon, Dec 8, priced at $502 found 2 days ago
Delta
Sat, Dec 6 - Wed, Dec 17
DSM
Des Moines
FCO
Rome
$506 Roundtrip, found 1 day ago
$506
Roundtrip
found 1 day ago
Select Delta flight, departing Sat, Dec 6 from Des Moines to Rome, returning Wed, Dec 17, priced at $506 found 1 day ago

Find the cheapest month to fly from Des Moines (DSM) to Rome (FCO)

January is typically the cheapest month to fly

From $532 - $1,560 per traveler.

Alternative airports near Rome

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Fiumicino - Leonardo da Vinci Intl. FCO. Cheapest option available. Average driving time to city center is 26 minutes. Flights from $1,021
FCO
Fiumicino - Leonardo da Vinci Intl.
Cheapest
Average driving time to city center26 min
Flights from $1,021

Frequently asked questions

How much does a flight from Des Moines Intl. Airport (DSM) to Fiumicino - Leonardo da Vinci Intl. Airport (FCO) cost?
Secure a cheap one-way flight from $395 or cheap return flight from $471 from Des Moines Intl. Airport (DSM) to Fiumicino - Leonardo da Vinci Intl. Airport (FCO) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Des Moines Intl. Airport (DSM) to Fiumicino - Leonardo da Vinci Intl. Airport (FCO)?
January is the most affordable month to fly from DSM to FCO. Avoiding peak travel times is often the key to finding better deals on flights.
What is the cheapest airline that flies from Des Moines Intl. Airport (DSM) to Fiumicino - Leonardo da Vinci Intl. Airport (FCO)?
To find the cheapest airline that'll fly you from DSM to FCO, use Expedia's filter tool. Tailor your search based on what's important to you, such as preferred carriers and number of stops. You can then sort your results by "Price (lowest to highest)" to list the most affordable options first.
How many flights per day from Des Moines Intl. Airport (DSM) to Fiumicino - Leonardo da Vinci Intl. Airport (FCO)?
There aren't any daily nonstop flights departing from Des Moines Intl. Airport (DSM) to Fiumicino - Leonardo da Vinci Intl. Airport (FCO). But you can choose flights with layovers. Filter your search on Expedia to include one or more stops, and you'll be cruising above the clouds in no time.
What day of the week has the most flights from DSM to FCO?
Typically you'll have the most choice when it comes to flights on a Friday. Tuesdays are often the quietest.* However, this can vary based on the season, airline and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Des Moines Intl. Airport (DSM) to Fiumicino - Leonardo da Vinci Intl. Airport (FCO)?
To avoid possible delays on the Des Moines Intl. Airport (DSM) to Fiumicino - Leonardo da Vinci Intl. Airport (FCO) route, fly before 3 PM. Departures after this hour have a 22% higher chance of being canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Des Moines Intl. Airport (DSM) to Fiumicino - Leonardo da Vinci Intl. Airport (FCO) last-minute?
Booking your plane ticket from DSM to FCO shortly before your trip is typically more expensive. But if you're flexible with your departure times and dates, you could land a cheap last-minute fare.
Is it cheaper to book a DSM to FCO flight and hotel package?
Booking a DSM to FCO flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your trip in one place. Choose from our impressive range of accommodations and then add car rentals, flights and activities to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Des Moines Intl. Airport (DSM) to Fiumicino - Leonardo da Vinci Intl. Airport (FCO)?
In most instances, you can cancel or reschedule your DSM to FCO flight. However, additional fees may apply, especially if you made your booking over 24 hours ago. Double-check your itinerary for the airline's rules and fees on flight changes, or if you'd like further information, head to our Customer Service portal.

Travel information

Origin airport
Des Moines Intl.
Destination airport
Fiumicino - Leonardo da Vinci Intl.
Airlines serving
Aer Lingus, Air Canada, Air France, American Airlines, British Airways, Delta, Finnair, Iberia, KLM, Lufthansa, Scandinavian Airlines, United
Roundtrip price
$470
Distance
5057 mi

Book with confidence

Des Moines to Rome Flights

The cheapest times to fly from Des Moines to Rome

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Des Moines to Rome are during the month of January. You can find some of the cheapest flights from Des Moines to Rome with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Des Moines to Rome

Sunday is one of the best days to book for cheap flights from Des Moines to Rome: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Des Moines to Rome

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Des Moines to Rome in 2025. You can also book with separate airlines for your outbound and return journeys, from $395 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Des Moines to Rome flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Des Moines to Rome airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Des Moines to Rome Flights

Explore a world of travel with Expedia

*Available to One Key members.