$140 Cheap Flights from Panama City (ECP) to Chicago (MDW)

View $140 flight on Wed, Oct 8, 2025Opens in a new window

Popular airlines from Northwest Florida Beaches Intl. Airport (ECP) to Chicago Midway Airport (MDW)

Cheap Flights from Panama City to Chicago (ECP-MDW)

Prices were available within the past 7 days and start at $140 for one-way flights and $287 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Southwest Airlines
Wed, Oct 15 - Wed, Oct 22
ECP
Panama City
MDW
Chicago
$287 Roundtrip, found 22 hours ago
$287
Roundtrip
found 22 hours ago
Select Southwest Airlines flight, departing Wed, Oct 15 from Panama City to Chicago, returning Wed, Oct 22, priced at $287 found 22 hours ago
Delta
Tue, Sep 23 - Tue, Sep 30
ECP
Panama City
MDW
Chicago
$287 Roundtrip, just found
$287
Roundtrip
just found
Select Delta flight, departing Tue, Sep 23 from Panama City to Chicago, returning Tue, Sep 30, priced at $287 just found
Southwest Airlines
Wed, Sep 24 - Sat, Sep 27
ECP
Panama City
MDW
Chicago
$287 Roundtrip, found 1 day ago
$287
Roundtrip
found 1 day ago
Select Southwest Airlines flight, departing Wed, Sep 24 from Panama City to Chicago, returning Sat, Sep 27, priced at $287 found 1 day ago
Delta
Tue, Jan 6 - Wed, Jan 7
ECP
Panama City
MDW
Chicago
$290 Roundtrip, found 8 hours ago
$290
Roundtrip
found 8 hours ago
Select Delta flight, departing Tue, Jan 6 from Panama City to Chicago, returning Wed, Jan 7, priced at $290 found 8 hours ago
Delta
Wed, Oct 22 - Sat, Nov 8
ECP
Panama City
MDW
Chicago
$291 Roundtrip, found 12 hours ago
$291
Roundtrip
found 12 hours ago
Select Delta flight, departing Wed, Oct 22 from Panama City to Chicago, returning Sat, Nov 8, priced at $291 found 12 hours ago
Southwest Airlines
Thu, Dec 18 - Tue, Dec 23
ECP
Panama City
MDW
Chicago
$292 Roundtrip, found 4 hours ago
$292
Roundtrip
found 4 hours ago
Select Southwest Airlines flight, departing Thu, Dec 18 from Panama City to Chicago, returning Tue, Dec 23, priced at $292 found 4 hours ago
Delta
Sat, Nov 1 - Mon, Nov 10
ECP
Panama City
MDW
Chicago
$295 Roundtrip, found 22 hours ago
$295
Roundtrip
found 22 hours ago
Select Delta flight, departing Sat, Nov 1 from Panama City to Chicago, returning Mon, Nov 10, priced at $295 found 22 hours ago
Delta
Sat, Oct 11 - Sat, Oct 25
ECP
Panama City
MDW
Chicago
$296 Roundtrip, found 12 hours ago
$296
Roundtrip
found 12 hours ago
Select Delta flight, departing Sat, Oct 11 from Panama City to Chicago, returning Sat, Oct 25, priced at $296 found 12 hours ago
Delta
Wed, Sep 24 - Sat, Sep 27
ECP
Panama City
MDW
Chicago
$296 Roundtrip, found 1 day ago
$296
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, Sep 24 from Panama City to Chicago, returning Sat, Sep 27, priced at $296 found 1 day ago
Southwest Airlines
Sat, Sep 27 - Sat, Oct 4
ECP
Panama City
MDW
Chicago
$297 Roundtrip, just found
$297
Roundtrip
just found
Select Southwest Airlines flight, departing Sat, Sep 27 from Panama City to Chicago, returning Sat, Oct 4, priced at $297 just found

Alternative airports near Chicago

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to O'Hare Intl. ORD. Cheapest option available. Average driving time to city center is 23 minutes. Flights from $421
ORD
O'Hare Intl.
Cheapest
Average driving time to city center23 min
Flights from $421
Flights from Panama City (ECP) to Chicago (MDW)
Origin airport
Northwest Florida Beaches Intl.
Destination airport
Midway Intl.
Airlines serving
Delta, Southwest Airlines
Roundtrip price
$286
Distance
797 mi
Average flight time
3 hours 30 mins

Panama City to Chicago Flights

The cheapest times to fly from Panama City to Chicago

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Panama City to Chicago are during the month of October. You can find some of the cheapest flights from Panama City to Chicago with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Panama City to Chicago

Sunday is one of the best days to book for cheap flights from Panama City to Chicago: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Panama City to Chicago

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Panama City to Chicago in 2025. You can also book with separate airlines for your outbound and return journeys, from $140 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Panama City to Chicago flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Panama City to Chicago airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Northwest Florida Beaches Intl. Airport (ECP) to Midway Intl. Airport (MDW) cost?
Grab a cheap one-way flight from $140 or cheap return flight from $287 from Northwest Florida Beaches Intl. Airport (ECP) to Midway Intl. Airport (MDW) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Northwest Florida Beaches Intl. Airport (ECP) to Midway Intl. Airport (MDW)?
Traveling in October is a great way to save, as it's the cheapest month for flights between ECP and MDW. You'll usually find the lowest prices during the off-season.
Which airlines fly direct from Northwest Florida Beaches Intl. Airport (ECP) to Midway Intl. Airport (MDW)?
While Panama City, FL (ECP-Northwest Florida Beaches Intl.) doesn't offer any direct flights to Midway Intl. Airport (MDW), other airports have nonstop options. Jetting off from Northwest Florida Regional Airport (VPS) will get you to Chicago without any detours.
What is the cheapest airline that flies from Northwest Florida Beaches Intl. Airport (ECP) to Midway Intl. Airport (MDW)?
Use the filter tool on Expedia to compare different airlines and find the most affordable carrier that'll take you from ECP to MDW. Then, sort your results by "Price (lowest to highest)" to snap up a great deal.
How many flights per day from Northwest Florida Beaches Intl. Airport (ECP) to Midway Intl. Airport (MDW)?
Direct flights from Northwest Florida Beaches Intl. Airport (ECP) to Midway Intl. Airport (MDW) aren't available daily, so you'll need to take a flight with a layover. Explore your options with Expedia's filters. Enter your travel dates and select either "1 Stop" or "2+ Stops."
What day of the week has the most flights from ECP to MDW?
Typically you'll find the largest variety of flight choices on a Friday. Tuesdays are often the quietest.* But this can change depending on the season, airline and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Northwest Florida Beaches Intl. Airport (ECP) to Midway Intl. Airport (MDW)?
To land at Midway Intl. Airport (MDW) on schedule, opt for a flight that leaves Northwest Florida Beaches Intl. Airport (ECP) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Northwest Florida Beaches Intl. Airport (ECP) to Midway Intl. Airport (MDW) last-minute?
Booking your plane ticket from ECP to MDW right before your journey is usually more expensive. But if you're flexible with your schedule, you could snag a cheap last-minute fare.
Is it cheaper to book an ECP to MDW flight and hotel package?
You'll typically save money by securing an ECP to MDW flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it's easy to manage it all in one convenient place. Once you've selected your preferred accommodations and flights, consider adding extras such as car rentals, activities and tours.
Can I cancel or change the date of my flight from Northwest Florida Beaches Intl. Airport (ECP) to Midway Intl. Airport (MDW)?
In most instances, you're able to reschedule or cancel your ECP to MDW flight. However, there may be additional fees, especially if you booked more than 24 hours ago. Check your itinerary for the airline's fees and rules on flight changes, or if you want further information, go to our Customer Service portal.

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*Available to One Key members.