$239 Cheap Flights from Key West (EYW) to Roanoke (ROA)

View $239 flight on Fri, Dec 19, 2025Opens in a new window

Popular airlines from Key West Intl. Airport (EYW) to Roanoke Regional Airport (ROA)

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Cheap Flights from Key West to Roanoke (EYW-ROA)

Prices were available within the past 7 days and start at $239 for one-way flights and $249 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Fri, Oct 31 - Mon, Nov 17
EYW
Key West
ROA
Roanoke
$249 Roundtrip, found 3 days ago
$249
Roundtrip
found 3 days ago
Select Delta flight, departing Fri, Oct 31 from Key West to Roanoke, returning Mon, Nov 17, priced at $249 found 3 days ago
Delta
Wed, Oct 8 - Tue, Oct 28
EYW
Key West
ROA
Roanoke
$254 Roundtrip, found 3 days ago
$254
Roundtrip
found 3 days ago
Select Delta flight, departing Wed, Oct 8 from Key West to Roanoke, returning Tue, Oct 28, priced at $254 found 3 days ago
Delta
Fri, Oct 24 - Tue, Nov 11
EYW
Key West
ROA
Roanoke
$266 Roundtrip, found 3 days ago
$266
Roundtrip
found 3 days ago
Select Delta flight, departing Fri, Oct 24 from Key West to Roanoke, returning Tue, Nov 11, priced at $266 found 3 days ago
Delta
Mon, Oct 6 - Sat, Oct 25
EYW
Key West
ROA
Roanoke
$271 Roundtrip, found 5 days ago
$271
Roundtrip
found 5 days ago
Select Delta flight, departing Mon, Oct 6 from Key West to Roanoke, returning Sat, Oct 25, priced at $271 found 5 days ago
Delta
Mon, Nov 3 - Mon, Nov 17
EYW
Key West
ROA
Roanoke
$274 Roundtrip, found 3 days ago
$274
Roundtrip
found 3 days ago
Select Delta flight, departing Mon, Nov 3 from Key West to Roanoke, returning Mon, Nov 17, priced at $274 found 3 days ago
Delta
Thu, Oct 30 - Mon, Nov 3
EYW
Key West
ROA
Roanoke
$294 Roundtrip, found 15 hours ago
$294
Roundtrip
found 15 hours ago
Select Delta flight, departing Thu, Oct 30 from Key West to Roanoke, returning Mon, Nov 3, priced at $294 found 15 hours ago
American Airlines
Thu, Oct 30 - Mon, Nov 3
EYW
Key West
ROA
Roanoke
$299 Roundtrip, found 15 hours ago
$299
Roundtrip
found 15 hours ago
Select American Airlines flight, departing Thu, Oct 30 from Key West to Roanoke, returning Mon, Nov 3, priced at $299 found 15 hours ago
American Airlines
Thu, Oct 9 - Mon, Oct 13
EYW
Key West
ROA
Roanoke
$304 Roundtrip, found 5 days ago
$304
Roundtrip
found 5 days ago
Select American Airlines flight, departing Thu, Oct 9 from Key West to Roanoke, returning Mon, Oct 13, priced at $304 found 5 days ago
American Airlines
Wed, Nov 19 - Mon, Dec 8
EYW
Key West
ROA
Roanoke
$319 Roundtrip, found 3 days ago
$319
Roundtrip
found 3 days ago
Select American Airlines flight, departing Wed, Nov 19 from Key West to Roanoke, returning Mon, Dec 8, priced at $319 found 3 days ago
United
Mon, Oct 27 - Tue, Nov 4
EYW
Key West
ROA
Roanoke
$567 Roundtrip, found 1 day ago
$567
Roundtrip
found 1 day ago
Select United flight, departing Mon, Oct 27 from Key West to Roanoke, returning Tue, Nov 4, priced at $567 found 1 day ago

Alternative airports near Roanoke

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Roanoke Regional ROA. Cheapest and Closest option available. Average driving time to city center is 9 minutes. Flights from $801
ROA
Roanoke Regional
CheapestClosest
Average driving time to city center9 min
Flights from $801

Frequently asked questions

How much does a flight from Key West Intl. Airport (EYW) to Roanoke Regional Airport (ROA) cost?
Get a cheap one-way flight from $239 or cheap return flight from $249 from Key West Intl. Airport (EYW) to Roanoke Regional Airport (ROA) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Key West Intl. Airport (EYW) to Roanoke Regional Airport (ROA)?
The cheapest month to fly from EYW to ROA is October, when there's less demand. Off-peak months are usually when you'll find lower airfares between these airports.
What is the cheapest airline that flies from Key West Intl. Airport (EYW) to Roanoke Regional Airport (ROA)?
Expedia's filter tool lets you easily compare airlines, flight times and fares all in one place. Select your preferences, then sort by "Price (lowest to highest)" to see which carrier offers the cheapest EYW to ROA flight.
How many flights per day from Key West Intl. Airport (EYW) to Roanoke Regional Airport (ROA)?
You'll have to book a flight with a layover if you're traveling from Key West Intl. Airport (EYW) to Roanoke Regional Airport (ROA). Direct flights don't operate daily on this route. However, just filter your search to include one or more stops to find the best option for your trip.
What day of the week has the most flights from EYW to ROA?
Friday is usually the busiest day for flights, while Tuesday tends to be the quietest.* Remember that flight schedules can vary depending on a range of factors, including the time of year and airline.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Key West Intl. Airport (EYW) to Roanoke Regional Airport (ROA)?
Opt for a flight from Key West Intl. Airport (EYW) to Roanoke Regional Airport (ROA) that takes off before 3 PM to reduce the risk of cancellations. Departures later than this have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Key West Intl. Airport (EYW) to Roanoke Regional Airport (ROA) last-minute?
Last-minute bookings from EYW to ROA are generally more expensive. To secure the best prices, start searching for flights well in advance. That said, if you can play around with your travel dates, you may find a cheap fare right before your journey.
Is it cheaper to book an EYW to ROA flight and hotel package?
You'll typically save money by booking an EYW to ROA flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's easy to manage it all in one convenient place. Once you've selected your ideal accommodations and flights, you can add extras such as tours, car rentals and activities.
Can I cancel or change the date of my flight from Key West Intl. Airport (EYW) to Roanoke Regional Airport (ROA)?
You can usually reschedule or cancel your EYW to ROA flight. However, if the booking was made more than 24 hours ago, additional fees may apply. Refer to your airline's policies in your itinerary to see what changes are possible and whether any costs are involved. You'll also find more information on our Customer Service portal.

Travel information

Travel information

Origin airport
Key West Intl.
Destination airport
Roanoke Regional
Airlines serving
American Airlines, Delta, United
Roundtrip price
$248
Distance
888 mi

Book with confidence

Book with confidence

Key West to Roanoke Flights

The cheapest times to fly from Key West to Roanoke

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Key West to Roanoke are during the month of October. You can find some of the cheapest flights from Key West to Roanoke with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Key West to Roanoke

Sunday is one of the best days to book for cheap flights from Key West to Roanoke: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Key West to Roanoke

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Key West to Roanoke in 2025. You can also book with separate airlines for your outbound and return journeys, from $239 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Key West to Roanoke flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Key West to Roanoke airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Key West to Roanoke Flights

Explore a world of travel with Expedia

Explore a world of travel with Expedia

*Available to One Key members.