$79 Cheap Flights from Islip (ISP) to Buffalo (BUF)

View $79 flight on Wed, Oct 22, 2025Opens in a new window

Popular airlines from MacArthur Airport (ISP) to Buffalo Niagara Intl. Airport (BUF)

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Cheap Flights from Islip to Buffalo (ISP-BUF)

Prices were available within the past 7 days and start at $79 for one-way flights and $178 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frontier Airlines
Sun, Nov 2 - Thu, Nov 13
ISP
Islip
BUF
Buffalo
$178 Roundtrip, found 1 hour ago
$178
Roundtrip
found 1 hour ago
Select Frontier Airlines flight, departing Sun, Nov 2 from Islip to Buffalo, returning Thu, Nov 13, priced at $178 found 1 hour ago
Southwest Airlines
Mon, Dec 8 - Wed, Dec 10
ISP
Islip
BUF
Buffalo
$185 Roundtrip, found 2 days ago
$185
Roundtrip
found 2 days ago
Select Southwest Airlines flight, departing Mon, Dec 8 from Islip to Buffalo, returning Wed, Dec 10, priced at $185 found 2 days ago
Southwest Airlines
Mon, Nov 3 - Fri, Nov 7
ISP
Islip
BUF
Buffalo
$187 Roundtrip, found 4 days ago
$187
Roundtrip
found 4 days ago
Select Southwest Airlines flight, departing Mon, Nov 3 from Islip to Buffalo, returning Fri, Nov 7, priced at $187 found 4 days ago
Southwest Airlines
Mon, Nov 3 - Fri, Nov 7
ISP
Islip
BUF
Buffalo
$193 Roundtrip, found 4 days ago
$193
Roundtrip
found 4 days ago
Select Southwest Airlines flight, departing Mon, Nov 3 from Islip to Buffalo, returning Fri, Nov 7, priced at $193 found 4 days ago
Frontier Airlines
Sun, Nov 2 - Fri, Nov 14
ISP
Islip
BUF
Buffalo
$194 Roundtrip, found 1 hour ago
$194
Roundtrip
found 1 hour ago
Select Frontier Airlines flight, departing Sun, Nov 2 from Islip to Buffalo, returning Fri, Nov 14, priced at $194 found 1 hour ago
Southwest Airlines
Sat, Oct 25 - Tue, Oct 28
ISP
Islip
BUF
Buffalo
$200 Roundtrip, found 2 days ago
$200
Roundtrip
found 2 days ago
Select Southwest Airlines flight, departing Sat, Oct 25 from Islip to Buffalo, returning Tue, Oct 28, priced at $200 found 2 days ago
Southwest Airlines
Thu, Dec 4 - Sun, Dec 7
ISP
Islip
BUF
Buffalo
$204 Roundtrip, found 3 days ago
$204
Roundtrip
found 3 days ago
Select Southwest Airlines flight, departing Thu, Dec 4 from Islip to Buffalo, returning Sun, Dec 7, priced at $204 found 3 days ago
Southwest Airlines
Sat, Oct 25 - Tue, Oct 28
ISP
Islip
BUF
Buffalo
$205 Roundtrip, found 2 days ago
$205
Roundtrip
found 2 days ago
Select Southwest Airlines flight, departing Sat, Oct 25 from Islip to Buffalo, returning Tue, Oct 28, priced at $205 found 2 days ago
Frontier Airlines
Thu, Oct 9 - Sat, Oct 11
ISP
Islip
BUF
Buffalo
$210 Roundtrip, found 3 hours ago
$210
Roundtrip
found 3 hours ago
Select Frontier Airlines flight, departing Thu, Oct 9 from Islip to Buffalo, returning Sat, Oct 11, priced at $210 found 3 hours ago
JetBlue Airways
Fri, Oct 31 - Tue, Nov 18
ISP
Islip
BUF
Buffalo
$257 Roundtrip, found 1 hour ago
$257
Roundtrip
found 1 hour ago
Select JetBlue Airways flight, departing Fri, Oct 31 from Islip to Buffalo, returning Tue, Nov 18, priced at $257 found 1 hour ago

Frequently asked questions

How much does a flight from MacArthur Airport (ISP) to Buffalo Niagara Intl. Airport (BUF) cost?
Lock in a cheap one-way flight from $79 or cheap return flight from $178 from MacArthur Airport (ISP) to Buffalo Niagara Intl. Airport (BUF) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from MacArthur Airport (ISP) to Buffalo Niagara Intl. Airport (BUF)?
Flying in November may help you find better deals, as it's the cheapest month for flights between ISP and BUF. You'll usually find the lowest fares during off-peak months.
Which airlines fly direct from MacArthur Airport (ISP) to Buffalo Niagara Intl. Airport (BUF)?
Although Islip, NY (ISP-MacArthur) doesn't have any direct flights to Buffalo Niagara Intl. Airport (BUF), other airports have nonstop routes. Traveling from John F. Kennedy Intl. Airport (JFK) will get you to Buffalo without any layovers.
What is the cheapest airline that flies from MacArthur Airport (ISP) to Buffalo Niagara Intl. Airport (BUF)?
Use the filter tool on Expedia to compare different airlines and find the most affordable carrier that'll fly you from ISP to BUF. Then, sort your results by "Price (lowest to highest)" to score a great deal.
How many flights per day from MacArthur Airport (ISP) to Buffalo Niagara Intl. Airport (BUF)?
You'll have to catch a flight with a layover when traveling from MacArthur Airport (ISP) to Buffalo Niagara Intl. Airport (BUF). Direct flights don't operate daily on this route. However, simply filter your search to include one or more stops to discover the best option for your trip.
What day of the week has the most flights from ISP to BUF?
Generally you'll have the most choice when it comes to flights on a Friday. Tuesdays tend to be the quietest.* However, this can change based on the time of year, carrier and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from MacArthur Airport (ISP) to Buffalo Niagara Intl. Airport (BUF)?
To arrive at Buffalo Niagara Intl. Airport (BUF) on schedule, choose a flight that leaves from MacArthur Airport (ISP) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from MacArthur Airport (ISP) to Buffalo Niagara Intl. Airport (BUF) last-minute?
Last-minute fares from ISP to BUF are usually more expensive. For the best rates, start looking for flights as soon as possible. That being said, if you can play around with your travel dates, you may land a cheap fare right before your journey.
Is it cheaper to book an ISP to BUF flight and hotel package?
You'll typically save money by booking an ISP to BUF flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it's simple to manage it all in one convenient place. After selecting your preferred accommodations and flights, you can add extras like activities, tours and car rentals.
Can I cancel or change the date of my flight from MacArthur Airport (ISP) to Buffalo Niagara Intl. Airport (BUF)?
In most instances, you can reschedule or cancel your ISP to BUF flight. However, there may be additional fees, especially if your booking was made more than 24 hours ago. Check your itinerary for the airline's fees and policies on flight changes, or if you need more details, go to our Customer Service portal.

Travel information

Travel information

Origin airport
MacArthur
Destination airport
Buffalo Niagara Intl.
Airlines serving
Frontier Airlines, JetBlue Airways, Southwest Airlines
Roundtrip price
$178
Distance
325 mi

Book with confidence

Book with confidence

Islip to Buffalo Flights

The cheapest times to fly from Islip to Buffalo

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Islip to Buffalo are during the month of November. You can find some of the cheapest flights from Islip to Buffalo with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Islip to Buffalo

Sunday is one of the best days to book for cheap flights from Islip to Buffalo: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Islip to Buffalo

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Islip to Buffalo in 2025. You can also book with separate airlines for your outbound and return journeys, from $79 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Islip to Buffalo flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Islip to Buffalo airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Islip to Buffalo Flights

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