$445 Cheap Flights from Medellín (MDE) to Manzanillo (ZLO)

View $445 flight on Wed, Nov 5, 2025Opens in a new window

Popular airlines from Jose Maria Cordova Intl. Airport (MDE) to Manzanillo, Colima (ZLO-Playa de Oro Intl.)

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Cheap Flights from Medellín to Manzanillo (MDE-ZLO)

Prices were available within the past 7 days and start at $445 for one-way flights and for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frequently asked questions

How much does a flight from Jose Maria Cordova Intl. Airport (MDE) to Playa de Oro Intl. Airport (ZLO) cost?
Lock in a cheap one-way flight from $445 or cheap return flight from Jose Maria Cordova Intl. Airport (MDE) to Playa de Oro Intl. Airport (ZLO) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Jose Maria Cordova Intl. Airport (MDE) to Playa de Oro Intl. Airport (ZLO)?
is the cheapest month to fly from MDE to ZLO. Traveling outside of peak seasons is often the key to finding better fares.
What is the cheapest airline that flies from Jose Maria Cordova Intl. Airport (MDE) to Playa de Oro Intl. Airport (ZLO)?
Use the filter tool on Expedia to compare different airlines and find the cheapest carrier that'll take you from MDE to ZLO. Then, sort your results by "Price (lowest to highest)" to snap up the best deal available.
How many flights per day from Jose Maria Cordova Intl. Airport (MDE) to Playa de Oro Intl. Airport (ZLO)?
You'll have to book a flight with a layover when traveling from Jose Maria Cordova Intl. Airport (MDE) to Playa de Oro Intl. Airport (ZLO). Direct flights don't operate daily on this route. However, simply filter your search to include one or more stops to find the best option for your trip.
What day of the week has the most flights from MDE to ZLO?
Friday is usually the busiest day for flights, while Tuesday is often the quietest.* Keep in mind that flight schedules can vary depending on a range of factors, including the carrier and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Jose Maria Cordova Intl. Airport (MDE) to Playa de Oro Intl. Airport (ZLO)?
To reach Playa de Oro Intl. Airport (ZLO) without delays, book a flight that leaves Jose Maria Cordova Intl. Airport (MDE) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Jose Maria Cordova Intl. Airport (MDE) to Playa de Oro Intl. Airport (ZLO) last-minute?
Last-minute bookings from MDE to ZLO are generally more expensive. For the best rates, start searching for flights as early as possible. That said, if you can play around with your travel dates, it's possible to land a cheap fare right before your journey.
Is it cheaper to book a MDE to ZLO flight and hotel package?
Compared with arranging hotels and flights separately, booking a MDE to ZLO flight and hotel package with Expedia could result in significant savings. Better yet, having it all in one place takes the hassle out of planning your trip. Just pick your flights and select from our extensive range of stays, then tailor your trip with extras like activities, tours and car rentals.
Can I cancel or change the date of my flight from Jose Maria Cordova Intl. Airport (MDE) to Playa de Oro Intl. Airport (ZLO)?
If you booked your MDE to ZLO flight within the last 24 hours, you may be able to cancel or modify it without any fees. Depending on the airline and the type of fare you have, additional charges may apply for changes beyond that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, visit our Customer Service portal if you'd like more information.

Travel information

Origin airport
José María Córdova Intl.
Destination airport
Playa de Oro Intl.
Distance
2153 mi

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Medellín to Manzanillo Flights

The cheapest times to fly from Medellín to Manzanillo

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Medellín to Manzanillo are during the month of . You can find some of the cheapest flights from Medellín to Manzanillo with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Medellín to Manzanillo

Sunday is one of the best days to book for cheap flights from Medellín to Manzanillo: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Medellín to Manzanillo

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Medellín to Manzanillo in 2025. You can also book with separate airlines for your outbound and return journeys, from $445 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Medellín to Manzanillo flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Medellín to Manzanillo airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Medellín to Manzanillo Flights

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*Available to One Key members.