$271 Cheap Flights from Harrisburg (MDT) to Key West (EYW)

View $271 flight on Thu, Jan 29, 2026Opens in a new window

Popular airlines from Harrisburg Intl. Airport (MDT) to Key West Intl. Airport (EYW)

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Cheap Flights from Harrisburg to Key West (MDT-EYW)

Prices were available within the past 7 days and start at $271 for one-way flights and $259 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Wed, Jan 28 - Thu, Feb 5
MDT
Harrisburg
EYW
Key West
$259 Roundtrip, found 3 hours ago
$259
Roundtrip
found 3 hours ago
Select American Airlines flight, departing Wed, Jan 28 from Harrisburg to Key West, returning Thu, Feb 5, priced at $259 found 3 hours ago
American Airlines
Thu, Jan 1 - Tue, Jan 6
MDT
Harrisburg
EYW
Key West
$264 Roundtrip, found 19 hours ago
$264
Roundtrip
found 19 hours ago
Select American Airlines flight, departing Thu, Jan 1 from Harrisburg to Key West, returning Tue, Jan 6, priced at $264 found 19 hours ago
Delta
Wed, Jan 14 - Tue, Jan 27
MDT
Harrisburg
EYW
Key West
$271 Roundtrip, found 7 hours ago
$271
Roundtrip
found 7 hours ago
Select Delta flight, departing Wed, Jan 14 from Harrisburg to Key West, returning Tue, Jan 27, priced at $271 found 7 hours ago
American Airlines
Fri, Nov 14 - Tue, Nov 18
MDT
Harrisburg
EYW
Key West
$274 Roundtrip, found 5 days ago
$274
Roundtrip
found 5 days ago
Select American Airlines flight, departing Fri, Nov 14 from Harrisburg to Key West, returning Tue, Nov 18, priced at $274 found 5 days ago
American Airlines
Thu, Jan 1 - Wed, Jan 7
MDT
Harrisburg
EYW
Key West
$281 Roundtrip, found 6 days ago
$281
Roundtrip
found 6 days ago
Select American Airlines flight, departing Thu, Jan 1 from Harrisburg to Key West, returning Wed, Jan 7, priced at $281 found 6 days ago
Delta
Mon, Dec 8 - Sat, Dec 13
MDT
Harrisburg
EYW
Key West
$281 Roundtrip, found 6 days ago
$281
Roundtrip
found 6 days ago
Select Delta flight, departing Mon, Dec 8 from Harrisburg to Key West, returning Sat, Dec 13, priced at $281 found 6 days ago
Delta
Tue, Feb 17 - Tue, Feb 24
MDT
Harrisburg
EYW
Key West
$283 Roundtrip, found 2 hours ago
$283
Roundtrip
found 2 hours ago
Select Delta flight, departing Tue, Feb 17 from Harrisburg to Key West, returning Tue, Feb 24, priced at $283 found 2 hours ago
Delta
Sun, Nov 16 - Wed, Dec 3
MDT
Harrisburg
EYW
Key West
$284 Roundtrip, found 1 day ago
$284
Roundtrip
found 1 day ago
Select Delta flight, departing Sun, Nov 16 from Harrisburg to Key West, returning Wed, Dec 3, priced at $284 found 1 day ago
American Airlines
Thu, Jan 1 - Wed, Jan 7
MDT
Harrisburg
EYW
Key West
$286 Roundtrip, found 6 days ago
$286
Roundtrip
found 6 days ago
Select American Airlines flight, departing Thu, Jan 1 from Harrisburg to Key West, returning Wed, Jan 7, priced at $286 found 6 days ago
United
Sun, Jan 4 - Sat, Jan 17
MDT
Harrisburg
EYW
Key West
$361 Roundtrip, found 22 hours ago
$361
Roundtrip
found 22 hours ago
Select United flight, departing Sun, Jan 4 from Harrisburg to Key West, returning Sat, Jan 17, priced at $361 found 22 hours ago

Find the cheapest month to fly from Harrisburg (MDT) to Key West (EYW)

September is typically the cheapest month to fly

From $258 - $558 per traveler.

Alternative airports near Key West

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Key West Intl. EYW. Cheapest and Closest option available. Average driving time to city center is 8 minutes. Flights from $444
EYW
Key West Intl.
CheapestClosest
Average driving time to city center8 min
Flights from $444

Frequently asked questions

How much does a flight from Harrisburg Intl. Airport (MDT) to Key West Intl. Airport (EYW) cost?
Snag a cheap one-way flight from $271 or cheap return flight from $259 from Harrisburg Intl. Airport (MDT) to Key West Intl. Airport (EYW) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Harrisburg Intl. Airport (MDT) to Key West Intl. Airport (EYW)?
The cheapest month to fly from MDT to EYW is January, when there's less demand. Off-peak season is often when airlines offer lower prices between these airports.
What is the cheapest airline that flies from Harrisburg Intl. Airport (MDT) to Key West Intl. Airport (EYW)?
Expedia's filter tool lets you easily compare airlines, flight times and baggage options all in one place. Customize the search to your preferences, then sort by "Price (lowest to highest)" to see which carrier offers the cheapest MDT to EYW flight.
How many flights per day from Harrisburg Intl. Airport (MDT) to Key West Intl. Airport (EYW)?
There are no daily nonstop flights from Harrisburg Intl. Airport (MDT) to Key West Intl. Airport (EYW). But you can book flights with layovers. Filter your search results on Expedia to include one or more stops, and you'll be on your way in no time.
What day of the week has the most flights from MDT to EYW?
Friday is usually the busiest day for flights, while Tuesday is often the quietest.* Keep in mind that flight schedules can vary based on various factors, including the time of year and carrier.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Harrisburg Intl. Airport (MDT) to Key West Intl. Airport (EYW)?
Opt for a flight from Harrisburg Intl. Airport (MDT) to Key West Intl. Airport (EYW) that takes off before 3 PM to reduce the risk of cancellations. Later departures have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Harrisburg Intl. Airport (MDT) to Key West Intl. Airport (EYW) last-minute?
Booking your plane ticket from MDT to EYW right before your getaway is typically more expensive. However, if there's some wiggle room with your travel dates and times, you could land a cheap last-minute fare.
Is it cheaper to book a MDT to EYW flight and hotel package?
Opting for a MDT to EYW flight and hotel package is generally cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your trip all in one place. Select from our extensive range of stays and then add activities, flights and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Harrisburg Intl. Airport (MDT) to Key West Intl. Airport (EYW)?
In most instances, you can cancel or reschedule your MDT to EYW flight. However, additional fees may apply, especially if you made your booking more than 24 hours ago. Check your itinerary for the airline's fees and policies on flight changes, or if you'd like more details, visit our Customer Service portal.

Travel information

Origin airport
Harrisburg Intl.
Destination airport
Key West Intl.
Airlines serving
American Airlines, Delta, United
Roundtrip price
$258
Distance
1118 mi

Book with confidence

Harrisburg to Key West Flights

The cheapest times to fly from Harrisburg to Key West

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Harrisburg to Key West are during the month of January. You can find some of the cheapest flights from Harrisburg to Key West with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Harrisburg to Key West

Sunday is one of the best days to book for cheap flights from Harrisburg to Key West: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Harrisburg to Key West

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Harrisburg to Key West in 2025. You can also book with separate airlines for your outbound and return journeys, from $271 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Harrisburg to Key West flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Harrisburg to Key West airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Harrisburg to Key West Flights

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*Available to One Key members.