$521 Cheap Flights from Harrisburg (MDT) to Palermo (PMO)

View $521 flight on Wed, Nov 19, 2025Opens in a new window

Popular airlines from Harrisburg Intl. Airport (MDT) to Punta Raisi Airport (PMO)

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Cheap Flights from Harrisburg to Palermo (MDT-PMO)

Prices were available within the past 7 days and start at $521 for one-way flights and $897 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

British Airways
Mon, Apr 20 - Mon, May 11
MDT
Harrisburg
PMO
Palermo
$897 Roundtrip, found 4 days ago
$897
Roundtrip
found 4 days ago
Select British Airways flight, departing Mon, Apr 20 from Harrisburg to Palermo, returning Mon, May 11, priced at $897 found 4 days ago
British Airways
Mon, Apr 20 - Mon, May 11
MDT
Harrisburg
PMO
Palermo
$1,016 Roundtrip, found 4 days ago
$1,016
Roundtrip
found 4 days ago
Select British Airways flight, departing Mon, Apr 20 from Harrisburg to Palermo, returning Mon, May 11, priced at $1,016 found 4 days ago
KLM
Mon, Oct 20 - Tue, Oct 28
MDT
Harrisburg
PMO
Palermo
$1,110 Roundtrip, found 5 days ago
$1,110
Roundtrip
found 5 days ago
Select KLM flight, departing Mon, Oct 20 from Harrisburg to Palermo, returning Tue, Oct 28, priced at $1,110 found 5 days ago
Air France
Wed, Oct 22 - Tue, Oct 28
MDT
Harrisburg
PMO
Palermo
$1,185 Roundtrip, found 5 days ago
$1,185
Roundtrip
found 5 days ago
Select Air France flight, departing Wed, Oct 22 from Harrisburg to Palermo, returning Tue, Oct 28, priced at $1,185 found 5 days ago
Lufthansa
Tue, Apr 21 - Tue, May 12
MDT
Harrisburg
PMO
Palermo
$1,256 Roundtrip, found 4 days ago
$1,256
Roundtrip
found 4 days ago
Select Lufthansa flight, departing Tue, Apr 21 from Harrisburg to Palermo, returning Tue, May 12, priced at $1,256 found 4 days ago
Lufthansa
Tue, Apr 21 - Tue, May 12
MDT
Harrisburg
PMO
Palermo
$1,260 Roundtrip, found 4 days ago
$1,260
Roundtrip
found 4 days ago
Select Lufthansa flight, departing Tue, Apr 21 from Harrisburg to Palermo, returning Tue, May 12, priced at $1,260 found 4 days ago
British Airways
Sat, Nov 22 - Sun, Nov 30
MDT
Harrisburg
PMO
Palermo
$1,286 Roundtrip, found 2 days ago
$1,286
Roundtrip
found 2 days ago
Select British Airways flight, departing Sat, Nov 22 from Harrisburg to Palermo, returning Sun, Nov 30, priced at $1,286 found 2 days ago
Lufthansa
Wed, Nov 19 - Fri, Nov 28
MDT
Harrisburg
PMO
Palermo
$1,329 Roundtrip, found 1 day ago
$1,329
Roundtrip
found 1 day ago
Select Lufthansa flight, departing Wed, Nov 19 from Harrisburg to Palermo, returning Fri, Nov 28, priced at $1,329 found 1 day ago
KLM
Mon, Oct 20 - Mon, Oct 27
MDT
Harrisburg
PMO
Palermo
$1,421 Roundtrip, found 5 days ago
$1,421
Roundtrip
found 5 days ago
Select KLM flight, departing Mon, Oct 20 from Harrisburg to Palermo, returning Mon, Oct 27, priced at $1,421 found 5 days ago
United
Sun, Oct 19 - Sun, Oct 26
MDT
Harrisburg
PMO
Palermo
$2,516 Roundtrip, found 5 days ago
$2,516
Roundtrip
found 5 days ago
Select United flight, departing Sun, Oct 19 from Harrisburg to Palermo, returning Sun, Oct 26, priced at $2,516 found 5 days ago

Frequently asked questions

How much does a flight from Harrisburg Intl. Airport (MDT) to Punta Raisi Airport (PMO) cost?
Snag a cheap one-way flight from $521 or cheap return flight from $897 from Harrisburg Intl. Airport (MDT) to Punta Raisi Airport (PMO) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Harrisburg Intl. Airport (MDT) to Punta Raisi Airport (PMO)?
Flying in April may help you find better deals, as it's the cheapest month for flights between MDT and PMO. You'll typically find the lowest prices during the off-season.
What is the cheapest airline that flies from Harrisburg Intl. Airport (MDT) to Punta Raisi Airport (PMO)?
Expedia's filter tool lets you easily compare airlines, flight times and fares all in one place. Select your preferences, then sort by "Price (lowest to highest)" to find the carrier with the cheapest MDT to PMO flight.
How many flights per day from Harrisburg Intl. Airport (MDT) to Punta Raisi Airport (PMO)?
Nonstop flights from Harrisburg Intl. Airport (MDT) to Punta Raisi Airport (PMO) aren't available daily, so you'll need to take a flight with a layover. Explore your options with our filter tool. Enter your dates and click on either "1 Stop" or "2+ Stops."
What day of the week has the most flights from MDT to PMO?
Friday is typically the busiest day for flights, while Tuesday is often the quietest.* Keep in mind that flight schedules can vary based on a number of factors, including the airline and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Harrisburg Intl. Airport (MDT) to Punta Raisi Airport (PMO)?
To avoid potential delays on the Harrisburg Intl. Airport (MDT) to Punta Raisi Airport (PMO) route, fly before 3 PM. Departures after this time have a 22% higher chance of being canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Harrisburg Intl. Airport (MDT) to Punta Raisi Airport (PMO) last-minute?
Waiting until just before your trip to book a ticket from MDT to PMO generally means paying more. Although you may find some last-minute discounts, they aren't always guaranteed. Keep your travel plans flexible to maximize your chances of getting a bargain.
Is it cheaper to book a MDT to PMO flight and hotel package?
Compared with arranging hotels and flights separately, booking a MDT to PMO flight and hotel package with Expedia could result in significant savings. Better yet, having everything in one place will take the hassle out of planning your trip. Simply secure your flights and choose from our wide range of hotels, then tailor your trip with extras like activities and car rentals.
Can I cancel or change the date of my flight from Harrisburg Intl. Airport (MDT) to Punta Raisi Airport (PMO)?
If you booked your MDT to PMO flight in the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of fare you have, additional charges may apply for changes beyond that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, go to our Customer Service portal if you want more information.

Travel information

Origin airport
Harrisburg Intl.
Destination airport
Punta Raisi
Airlines serving
American Airlines, British Airways, Lufthansa
Roundtrip price
$896
Distance
4587 mi

Book with confidence

Harrisburg to Palermo Flights

The cheapest times to fly from Harrisburg to Palermo

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Harrisburg to Palermo are during the month of April. You can find some of the cheapest flights from Harrisburg to Palermo with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Harrisburg to Palermo

Sunday is one of the best days to book for cheap flights from Harrisburg to Palermo: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Harrisburg to Palermo

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Harrisburg to Palermo in 2025. You can also book with separate airlines for your outbound and return journeys, from $521 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Harrisburg to Palermo flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Harrisburg to Palermo airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Harrisburg to Palermo Flights

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*Available to One Key members.