$151 Cheap Flights from Medford (MFR) to Indianapolis (IND)

View $151 flight on Sun, Aug 31, 2025Opens in a new window

Popular airlines from Rogue Valley Intl. Airport (MFR) to Indianapolis Intl. Airport (IND)

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Cheap Flights from Medford to Indianapolis (MFR-IND)

Prices were available within the past 7 days and start at $151 for one-way flights and $294 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Wed, Sep 17 - Wed, Sep 24
MFR
Medford
IND
Indianapolis
$294 Roundtrip, found 2 hours ago
$294
Roundtrip
found 2 hours ago
Select Delta flight, departing Wed, Sep 17 from Medford to Indianapolis, returning Wed, Sep 24, priced at $294 found 2 hours ago
Delta
Wed, Aug 20 - Mon, Aug 25
MFR
Medford
IND
Indianapolis
$304 Roundtrip, found 20 hours ago
$304
Roundtrip
found 20 hours ago
Select Delta flight, departing Wed, Aug 20 from Medford to Indianapolis, returning Mon, Aug 25, priced at $304 found 20 hours ago
Delta
Fri, Oct 31 - Wed, Nov 5
MFR
Medford
IND
Indianapolis
$306 Roundtrip, found 3 days ago
$306
Roundtrip
found 3 days ago
Select Delta flight, departing Fri, Oct 31 from Medford to Indianapolis, returning Wed, Nov 5, priced at $306 found 3 days ago
Delta
Fri, Oct 31 - Wed, Nov 5
MFR
Medford
IND
Indianapolis
$311 Roundtrip, found 3 days ago
$311
Roundtrip
found 3 days ago
Select Delta flight, departing Fri, Oct 31 from Medford to Indianapolis, returning Wed, Nov 5, priced at $311 found 3 days ago
Delta
Tue, Oct 21 - Mon, Oct 27
MFR
Medford
IND
Indianapolis
$322 Roundtrip, found 2 days ago
$322
Roundtrip
found 2 days ago
Select Delta flight, departing Tue, Oct 21 from Medford to Indianapolis, returning Mon, Oct 27, priced at $322 found 2 days ago
Delta
Fri, Oct 24 - Mon, Oct 27
MFR
Medford
IND
Indianapolis
$332 Roundtrip, found 2 days ago
$332
Roundtrip
found 2 days ago
Select Delta flight, departing Fri, Oct 24 from Medford to Indianapolis, returning Mon, Oct 27, priced at $332 found 2 days ago
Alaska Airlines
Tue, Aug 12 - Sun, Aug 31
MFR
Medford
IND
Indianapolis
$339 Roundtrip, found 4 days ago
$339
Roundtrip
found 4 days ago
Select Alaska Airlines flight, departing Tue, Aug 12 from Medford to Indianapolis, returning Sun, Aug 31, priced at $339 found 4 days ago
Hawaiian Airlines
Fri, Sep 19 - Tue, Sep 23
MFR
Medford
IND
Indianapolis
$352 Roundtrip, found 2 hours ago
$352
Roundtrip
found 2 hours ago
Select Hawaiian Airlines flight, departing Fri, Sep 19 from Medford to Indianapolis, returning Tue, Sep 23, priced at $352 found 2 hours ago
United
Wed, Sep 24 - Sat, Sep 27
MFR
Medford
IND
Indianapolis
$368 Roundtrip, found 1 day ago
$368
Roundtrip
found 1 day ago
Select United flight, departing Wed, Sep 24 from Medford to Indianapolis, returning Sat, Sep 27, priced at $368 found 1 day ago
American Airlines
Wed, Sep 24 - Sat, Sep 27
MFR
Medford
IND
Indianapolis
$379 Roundtrip, found 1 day ago
$379
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Sep 24 from Medford to Indianapolis, returning Sat, Sep 27, priced at $379 found 1 day ago

Find the cheapest month to fly from Medford (MFR) to Indianapolis (IND)

September is typically the cheapest month to fly

From $235 - $596 per traveler.

Graph displaying average flight prices per month

Alternative airports near Indianapolis

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Indianapolis Intl. IND. Cheapest and Closest option available. Average driving time to city center is 19 minutes. Flights from $505
IND
Indianapolis Intl.
CheapestClosest
Average driving time to city center19 min
Flights from $505
Flights from Medford (MFR) to Indianapolis (IND)
Origin airport
Rogue Valley Intl.
Destination airport
Indianapolis Intl.
Airlines serving
Alaska Airlines, American Airlines, Delta, Hawaiian Airlines, United
Roundtrip price
$293
Distance
1899 mi

Medford to Indianapolis Flights

The cheapest times to fly from Medford to Indianapolis

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Medford to Indianapolis are during the month of September. You can find some of the cheapest flights from Medford to Indianapolis with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Medford to Indianapolis

Sunday is one of the best days to book for cheap flights from Medford to Indianapolis: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Medford to Indianapolis

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Medford to Indianapolis in 2025. You can also book with separate airlines for your outbound and return journeys, from $151 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Medford to Indianapolis flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Medford to Indianapolis airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Rogue Valley Intl. Airport (MFR) to Indianapolis Intl. Airport (IND) cost?
Discover the latest flight deals from MFR to IND by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from MFR to IND?
The cheapest flights from MFR to IND are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from MFR to IND?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that'll take you from MFR to IND. Sort your results by "Price (lowest to highest)" to snap up a great deal.
How many flights per day from Rogue Valley Intl. Airport (MFR) to Indianapolis Intl. Airport (IND)?
Nonstop flights from Rogue Valley Intl. Airport (MFR) to Indianapolis Intl. Airport (IND) aren't available daily, so you'll have to take a flight with a layover. Explore your options with Expedia's filter tool. Enter your travel dates and choose either "1 Stop" or "2+ Stops."
What day of the week has the most flights from MFR to IND?
Friday is typically the busiest day for flights, while Tuesday is often the quietest.* Remember that flight schedules can change depending on a range of factors, such as the carrier and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Rogue Valley Intl. Airport (MFR) to Indianapolis Intl. Airport (IND)?
To land at Indianapolis Intl. Airport (IND) without delays, pick a flight that leaves from Rogue Valley Intl. Airport (MFR) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Rogue Valley Intl. Airport (MFR) to Indianapolis Intl. Airport (IND) last-minute?
Waiting until just before your departure to book your flight from MFR to IND often results in higher prices. Although you may find some last-minute discounts, there's no guarantee. Be flexible with your itinerary for the best chance of snagging a bargain.
Is it cheaper to book a MFR to IND flight and hotel package?
Booking a MFR to IND flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Pick from our impressive range of accommodations and then add flights, activities and car rentals to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Rogue Valley Intl. Airport (MFR) to Indianapolis Intl. Airport (IND)?
It's usually possible to cancel or reschedule your MFR to IND flight. However, if the booking was made more than 24 hours ago, additional charges may apply. Check your airline's policies in your itinerary to see what changes are possible and whether any costs are involved. You'll also find more information on our Customer Service portal.

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*Available to One Key members.