$165 Cheap Flights from Medford (MFR) to Indianapolis (IND)

View $165 flight on Tue, Dec 9, 2025Opens in a new window

Popular airlines from Rogue Valley Intl. Airport (MFR) to Indianapolis Intl. Airport (IND)

    notification illustration

    Be in the know

    Get alerts if flight prices drop or rise*
    deals illustration

    Book smarter

    Save up to 30% on select hotels after you book a flight*
    trophy illustration

    Earn twice

    Earn your airline miles on top of our OneKeyCash
    Learn about One Key

Cheap Flights from Medford to Indianapolis (MFR-IND)

Prices were available within the past 7 days and start at $165 for one-way flights and $274 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Tue, Jan 6 - Wed, Jan 21
MFR
Medford
IND
Indianapolis
$274 Roundtrip, found 3 days ago
$274
Roundtrip
found 3 days ago
Select Delta flight, departing Tue, Jan 6 from Medford to Indianapolis, returning Wed, Jan 21, priced at $274 found 3 days ago
Delta
Tue, Dec 2 - Sat, Dec 6
MFR
Medford
IND
Indianapolis
$283 Roundtrip, found 4 days ago
$283
Roundtrip
found 4 days ago
Select Delta flight, departing Tue, Dec 2 from Medford to Indianapolis, returning Sat, Dec 6, priced at $283 found 4 days ago
Delta
Tue, Jan 6 - Thu, Jan 22
MFR
Medford
IND
Indianapolis
$284 Roundtrip, found 3 days ago
$284
Roundtrip
found 3 days ago
Select Delta flight, departing Tue, Jan 6 from Medford to Indianapolis, returning Thu, Jan 22, priced at $284 found 3 days ago
Delta
Tue, Dec 9 - Tue, Dec 16
MFR
Medford
IND
Indianapolis
$290 Roundtrip, just found
$290
Roundtrip
just found
Select Delta flight, departing Tue, Dec 9 from Medford to Indianapolis, returning Tue, Dec 16, priced at $290 just found
Delta
Tue, Dec 2 - Mon, Dec 8
MFR
Medford
IND
Indianapolis
$293 Roundtrip, found 4 days ago
$293
Roundtrip
found 4 days ago
Select Delta flight, departing Tue, Dec 2 from Medford to Indianapolis, returning Mon, Dec 8, priced at $293 found 4 days ago
Delta
Thu, Jan 8 - Thu, Jan 22
MFR
Medford
IND
Indianapolis
$294 Roundtrip, found 3 days ago
$294
Roundtrip
found 3 days ago
Select Delta flight, departing Thu, Jan 8 from Medford to Indianapolis, returning Thu, Jan 22, priced at $294 found 3 days ago
Alaska Airlines
Tue, Nov 18 - Wed, Nov 26
MFR
Medford
IND
Indianapolis
$322 Roundtrip, found 3 days ago
$322
Roundtrip
found 3 days ago
Select Alaska Airlines flight, departing Tue, Nov 18 from Medford to Indianapolis, returning Wed, Nov 26, priced at $322 found 3 days ago
Hawaiian Airlines
Tue, Nov 18 - Tue, Nov 25
MFR
Medford
IND
Indianapolis
$322 Roundtrip, found 23 hours ago
$322
Roundtrip
found 23 hours ago
Select Hawaiian Airlines flight, departing Tue, Nov 18 from Medford to Indianapolis, returning Tue, Nov 25, priced at $322 found 23 hours ago
American Airlines
Tue, Dec 9 - Tue, Dec 16
MFR
Medford
IND
Indianapolis
$371 Roundtrip, just found
$371
Roundtrip
just found
Select American Airlines flight, departing Tue, Dec 9 from Medford to Indianapolis, returning Tue, Dec 16, priced at $371 just found
United
Tue, Dec 9 - Tue, Dec 16
MFR
Medford
IND
Indianapolis
$371 Roundtrip, just found
$371
Roundtrip
just found
Select United flight, departing Tue, Dec 9 from Medford to Indianapolis, returning Tue, Dec 16, priced at $371 just found

Find the cheapest month to fly from Medford (MFR) to Indianapolis (IND)

September is typically the cheapest month to fly

From $278 - $561 per traveler.

Alternative airports near Indianapolis

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Indianapolis Intl. IND. Cheapest and Closest option available. Average driving time to city center is 19 minutes. Flights from $474
IND
Indianapolis Intl.
CheapestClosest
Average driving time to city center19 min
Flights from $474

Frequently asked questions

How much does a flight from Rogue Valley Intl. Airport (MFR) to Indianapolis Intl. Airport (IND) cost?
Lock in a cheap one-way flight from $165 or cheap return flight from $274 from Rogue Valley Intl. Airport (MFR) to Indianapolis Intl. Airport (IND) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Rogue Valley Intl. Airport (MFR) to Indianapolis Intl. Airport (IND)?
The cheapest month to fly from MFR to IND is January, when demand is low. Off-peak months are typically when better flight deals are available between these airports.
What is the cheapest airline that flies from Rogue Valley Intl. Airport (MFR) to Indianapolis Intl. Airport (IND)?
Use the filter tool on Expedia to compare different airlines and find the cheapest carrier that'll take you from MFR to IND. Then, sort your results by "Price (lowest to highest)" to snag a good deal.
How many flights per day from Rogue Valley Intl. Airport (MFR) to Indianapolis Intl. Airport (IND)?
Nonstop flights from Rogue Valley Intl. Airport (MFR) to Indianapolis Intl. Airport (IND) aren't available daily, so you'll have to take a flight with a layover. Explore your options with Expedia's filter tool. Enter your travel dates and choose either "1 Stop" or "2+ Stops."
What day of the week has the most flights from MFR to IND?
Friday is typically the busiest day for flights, while Tuesday is often the quietest.* Remember that flight schedules can change depending on a range of factors, such as the carrier and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Rogue Valley Intl. Airport (MFR) to Indianapolis Intl. Airport (IND)?
To land at Indianapolis Intl. Airport (IND) without delays, pick a flight that leaves from Rogue Valley Intl. Airport (MFR) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Rogue Valley Intl. Airport (MFR) to Indianapolis Intl. Airport (IND) last-minute?
Waiting until just before your departure to book your flight from MFR to IND often results in higher prices. Although you may find some last-minute discounts, there's no guarantee. Be flexible with your itinerary for the best chance of snagging a bargain.
Is it cheaper to book a MFR to IND flight and hotel package?
Booking a MFR to IND flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Pick from our impressive range of accommodations and then add flights, activities and car rentals to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Rogue Valley Intl. Airport (MFR) to Indianapolis Intl. Airport (IND)?
It's usually possible to cancel or reschedule your MFR to IND flight. However, if the booking was made more than 24 hours ago, additional charges may apply. Check your airline's policies in your itinerary to see what changes are possible and whether any costs are involved. You'll also find more information on our Customer Service portal.

Travel information

Origin airport
Rogue Valley Intl.
Destination airport
Indianapolis Intl.
Airlines serving
Alaska Airlines, American Airlines, Delta, Hawaiian Airlines, United
Roundtrip price
$273
Distance
1899 mi

Book with confidence

Medford to Indianapolis Flights

The cheapest times to fly from Medford to Indianapolis

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Medford to Indianapolis are during the month of January. You can find some of the cheapest flights from Medford to Indianapolis with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Medford to Indianapolis

Sunday is one of the best days to book for cheap flights from Medford to Indianapolis: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Medford to Indianapolis

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Medford to Indianapolis in 2025. You can also book with separate airlines for your outbound and return journeys, from $165 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Medford to Indianapolis flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Medford to Indianapolis airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Medford to Indianapolis Flights

Explore a world of travel with Expedia

*Available to One Key members.