$518 Cheap Flights from Mobile (MOB) to Santiago (SCL)

View $518 flight on Mon, Dec 29, 2025Opens in a new window

Popular airlines from Mobile Regional Airport (MOB) to Santiago Intl. Airport (SCL)

Cheap Flights from Mobile to Santiago (MOB-SCL)

Prices were available within the past 7 days and start at $518 for one-way flights and $754 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

United
Thu, Jan 8 - Wed, Jan 28
MOB
Mobile
SCL
Santiago
$754 Roundtrip, found 2 days ago
$754
Roundtrip
found 2 days ago
Select United flight, departing Thu, Jan 8 from Mobile to Santiago, returning Wed, Jan 28, priced at $754 found 2 days ago
American Airlines
Sun, Nov 30 - Mon, Dec 29
MOB
Mobile
SCL
Santiago
$756 Roundtrip, found 1 day ago
$756
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sun, Nov 30 from Mobile to Santiago, returning Mon, Dec 29, priced at $756 found 1 day ago
United
Thu, Jan 8 - Tue, Jan 27
MOB
Mobile
SCL
Santiago
$758 Roundtrip, found 2 days ago
$758
Roundtrip
found 2 days ago
Select United flight, departing Thu, Jan 8 from Mobile to Santiago, returning Tue, Jan 27, priced at $758 found 2 days ago
United
Sun, Jan 18 - Wed, Feb 4
MOB
Mobile
SCL
Santiago
$776 Roundtrip, found 2 days ago
$776
Roundtrip
found 2 days ago
Select United flight, departing Sun, Jan 18 from Mobile to Santiago, returning Wed, Feb 4, priced at $776 found 2 days ago
Delta
Thu, Feb 26 - Mon, Mar 16
MOB
Mobile
SCL
Santiago
$778 Roundtrip, found 2 days ago
$778
Roundtrip
found 2 days ago
Select Delta flight, departing Thu, Feb 26 from Mobile to Santiago, returning Mon, Mar 16, priced at $778 found 2 days ago
Delta
Sun, Jan 25 - Mon, Feb 9
MOB
Mobile
SCL
Santiago
$781 Roundtrip, found 2 days ago
$781
Roundtrip
found 2 days ago
Select Delta flight, departing Sun, Jan 25 from Mobile to Santiago, returning Mon, Feb 9, priced at $781 found 2 days ago
United
Sun, Nov 30 - Mon, Dec 29
MOB
Mobile
SCL
Santiago
$786 Roundtrip, found 1 day ago
$786
Roundtrip
found 1 day ago
Select United flight, departing Sun, Nov 30 from Mobile to Santiago, returning Mon, Dec 29, priced at $786 found 1 day ago
American Airlines
Sun, Nov 30 - Mon, Dec 29
MOB
Mobile
SCL
Santiago
$788 Roundtrip, found 1 day ago
$788
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sun, Nov 30 from Mobile to Santiago, returning Mon, Dec 29, priced at $788 found 1 day ago
Delta
Wed, Dec 3 - Tue, Dec 30
MOB
Mobile
SCL
Santiago
$793 Roundtrip, found 1 day ago
$793
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, Dec 3 from Mobile to Santiago, returning Tue, Dec 30, priced at $793 found 1 day ago
American Airlines
Sun, Nov 30 - Mon, Dec 29
MOB
Mobile
SCL
Santiago
$796 Roundtrip, found 1 day ago
$796
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sun, Nov 30 from Mobile to Santiago, returning Mon, Dec 29, priced at $796 found 1 day ago
Flights from Mobile (MOB) to Santiago (SCL)
Origin airport
Mobile Regional
Destination airport
Arturo Merino Benitez
Airlines serving
Air Canada, American Airlines, Delta, United
Roundtrip price
$753
Distance
4571 mi

Mobile to Santiago Flights

The cheapest times to fly from Mobile to Santiago

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Mobile to Santiago are during the month of January. You can find some of the cheapest flights from Mobile to Santiago with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Mobile to Santiago

Sunday is one of the best days to book for cheap flights from Mobile to Santiago: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Mobile to Santiago

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Mobile to Santiago in 2025. You can also book with separate airlines for your outbound and return journeys, from $518 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Mobile to Santiago flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Mobile to Santiago airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Mobile Regional Airport (MOB) to Arturo Merino Benitez Airport (SCL) cost?
Lock in a cheap one-way flight from $518 or cheap return flight from $754 from Mobile Regional Airport (MOB) to Arturo Merino Benitez Airport (SCL) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Mobile Regional Airport (MOB) to Arturo Merino Benitez Airport (SCL)?
The cheapest month to fly from MOB to SCL is January, when demand is low. Off-peak season is usually when airlines offer better prices between these airports.
What is the cheapest airline that flies from Mobile Regional Airport (MOB) to Arturo Merino Benitez Airport (SCL)?
To find the cheapest airline flying from MOB to SCL, use Expedia's filter tool. Customize your search based on what matters most to you, such as preferred carriers and ideal departure window. You can then sort your results by "Price (lowest to highest)" to see the most affordable options first.
How many flights per day from Mobile Regional Airport (MOB) to Arturo Merino Benitez Airport (SCL)?
You'll need to catch a flight with a layover when traveling from Mobile Regional Airport (MOB) to Arturo Merino Benitez Airport (SCL). Direct flights don't operate daily on this route. However, simply filter your search to include one or two stops to discover the best option for your trip.
What day of the week has the most flights from MOB to SCL?
Friday is usually the busiest day for flights, while Tuesday tends to be the quietest.* Just remember that flight schedules can change based on a number of factors, including the time of year and carrier.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Mobile Regional Airport (MOB) to Arturo Merino Benitez Airport (SCL)?
Opt for a flight from Mobile Regional Airport (MOB) to Arturo Merino Benitez Airport (SCL) that takes off before 3 PM to reduce the risk of delays and cancellations. Departures after this hour have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Mobile Regional Airport (MOB) to Arturo Merino Benitez Airport (SCL) last-minute?
Holding off until right before your break to book a ticket from MOB to SCL generally means paying more. Although you may find some last-minute discounts, they're not always guaranteed. Keep your travel plans flexible for a better chance of getting a bargain.
Is it cheaper to book a MOB to SCL flight and hotel package?
You'll typically save money by booking a MOB to SCL flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it's simple to manage it all in one place. After choosing your preferred accommodations and flights, you can add extras like activities, car rentals and tours.
Can I cancel or change the date of my flight from Mobile Regional Airport (MOB) to Arturo Merino Benitez Airport (SCL)?
If you reserved your MOB to SCL flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you purchased, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you want more information.

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*Available to One Key members.