$400 Cheap Flights from Minneapolis (MSP) to Santiago (SCL)

View $400 flight on Fri, Mar 6, 2026Opens in a new window

Popular airlines from Minneapolis - St. Paul Intl. Airport (MSP) to Santiago Intl. Airport (SCL)

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Cheap Flights from Minneapolis to Santiago (MSP-SCL)

Prices were available within the past 7 days and start at $400 for one-way flights and $783 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Air Canada
Tue, Nov 18 - Thu, Nov 27
MSP
Minneapolis
SCL
Santiago
$783 Roundtrip, found 1 hour ago
$783
Roundtrip
found 1 hour ago
Select Air Canada flight, departing Tue, Nov 18 from Minneapolis to Santiago, returning Thu, Nov 27, priced at $783 found 1 hour ago
Air Canada
Mon, Jan 26 - Sat, Feb 14
MSP
Minneapolis
SCL
Santiago
$828 Roundtrip, found 1 hour ago
$828
Roundtrip
found 1 hour ago
Select Air Canada flight, departing Mon, Jan 26 from Minneapolis to Santiago, returning Sat, Feb 14, priced at $828 found 1 hour ago
Air Canada
Sun, Feb 1 - Thu, Feb 5
MSP
Minneapolis
SCL
Santiago
$833 Roundtrip, found 1 hour ago
$833
Roundtrip
found 1 hour ago
Select Air Canada flight, departing Sun, Feb 1 from Minneapolis to Santiago, returning Thu, Feb 5, priced at $833 found 1 hour ago
Air Canada
Tue, Dec 30 - Thu, Jan 22
MSP
Minneapolis
SCL
Santiago
$873 Roundtrip, found 1 hour ago
$873
Roundtrip
found 1 hour ago
Select Air Canada flight, departing Tue, Dec 30 from Minneapolis to Santiago, returning Thu, Jan 22, priced at $873 found 1 hour ago
American Airlines
Thu, Mar 5 - Thu, Mar 19
MSP
Minneapolis
SCL
Santiago
$914 Roundtrip, just found
$914
Roundtrip
just found
Select American Airlines flight, departing Thu, Mar 5 from Minneapolis to Santiago, returning Thu, Mar 19, priced at $914 just found
Delta
Thu, Mar 5 - Thu, Mar 19
MSP
Minneapolis
SCL
Santiago
$914 Roundtrip, just found
$914
Roundtrip
just found
Select Delta flight, departing Thu, Mar 5 from Minneapolis to Santiago, returning Thu, Mar 19, priced at $914 just found
United
Thu, Mar 5 - Thu, Mar 19
MSP
Minneapolis
SCL
Santiago
$914 Roundtrip, just found
$914
Roundtrip
just found
Select United flight, departing Thu, Mar 5 from Minneapolis to Santiago, returning Thu, Mar 19, priced at $914 just found
Air Canada
Tue, Dec 30 - Tue, Jan 20
MSP
Minneapolis
SCL
Santiago
$918 Roundtrip, found 1 day ago
$918
Roundtrip
found 1 day ago
Select Air Canada flight, departing Tue, Dec 30 from Minneapolis to Santiago, returning Tue, Jan 20, priced at $918 found 1 day ago
American Airlines
Thu, Mar 5 - Thu, Mar 19
MSP
Minneapolis
SCL
Santiago
$919 Roundtrip, just found
$919
Roundtrip
just found
Select American Airlines flight, departing Thu, Mar 5 from Minneapolis to Santiago, returning Thu, Mar 19, priced at $919 just found
Copa
Wed, Nov 19 - Mon, Nov 24
MSP
Minneapolis
SCL
Santiago
$929 Roundtrip, found 6 days ago
$929
Roundtrip
found 6 days ago
Select Copa flight, departing Wed, Nov 19 from Minneapolis to Santiago, returning Mon, Nov 24, priced at $929 found 6 days ago

Find the cheapest month to fly from Minneapolis (MSP) to Santiago (SCL)

May is typically the cheapest month to fly

From $755 - $1,368 per traveler.

Alternative airports near Santiago

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Arturo Merino Benitez SCL. Cheapest and Closest option available. Average driving time to city center is 17 minutes. Flights from $783
SCL
Arturo Merino Benitez
CheapestClosest
Average driving time to city center17 min
Flights from $783

Frequently asked questions

How much does a flight from Minneapolis - St. Paul Intl. Airport (MSP) to Arturo Merino Benitez Airport (SCL) cost?
Lock in a cheap one-way flight from $400 or cheap return flight from $783 from Minneapolis - St. Paul Intl. Airport (MSP) to Arturo Merino Benitez Airport (SCL) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Minneapolis - St. Paul Intl. Airport (MSP) to Arturo Merino Benitez Airport (SCL)?
Flying in November is a great way to save, as it's the cheapest month for flights between MSP and SCL. You'll often find the lowest fares during the off-season.
What is the cheapest airline that flies from Minneapolis - St. Paul Intl. Airport (MSP) to Arturo Merino Benitez Airport (SCL)?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that'll take you from MSP to SCL. Then, sort your results by "Price (lowest to highest)" to score a great deal.
How many flights per day from Minneapolis - St. Paul Intl. Airport (MSP) to Arturo Merino Benitez Airport (SCL)?
You'll need to take a flight with a layover if you're traveling from Minneapolis - St. Paul Intl. Airport (MSP) to Arturo Merino Benitez Airport (SCL). Direct flights don't operate daily on this route. However, just filter your search to include one or two stops to find an option that works for you.
What day of the week has the most flights from MSP to SCL?
Generally you'll find the greatest selection of flight options on a Friday. Tuesdays are often the quietest.* But this can vary depending on the time of year, airline and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Minneapolis - St. Paul Intl. Airport (MSP) to Arturo Merino Benitez Airport (SCL)?
To land at Arturo Merino Benitez Airport (SCL) on time, choose a flight that leaves from Minneapolis - St. Paul Intl. Airport (MSP) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Minneapolis - St. Paul Intl. Airport (MSP) to Arturo Merino Benitez Airport (SCL) last-minute?
Booking your plane ticket from MSP to SCL right before your journey is generally more expensive. But if there's some wiggle room with your travel times and dates, you could bag a cheap last-minute fare.
Is it cheaper to book a MSP to SCL flight and hotel package?
Securing a MSP to SCL flight and hotel package is typically cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your trip all in one place. Choose from our wide range of hotels and then add activities, car rentals and flights to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Minneapolis - St. Paul Intl. Airport (MSP) to Arturo Merino Benitez Airport (SCL)?
Generally, it's possible to reschedule or cancel your MSP to SCL flight. However, if the booking was made more than 24 hours ago, additional charges may apply. Check your airline's policies in your itinerary to see what changes are allowed and if any costs are involved. You'll also find more details on our Customer Service portal.

Travel information

Origin airport
Minneapolis - St. Paul Intl.
Destination airport
Arturo Merino Benitez
Airlines serving
Air Canada, American Airlines, Copa, Delta, LATAM Airlines Group, United
Roundtrip price
$782
Distance
5588 mi

Book with confidence

Minneapolis to Santiago Flights

The cheapest times to fly from Minneapolis to Santiago

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Minneapolis to Santiago are during the month of November. You can find some of the cheapest flights from Minneapolis to Santiago with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Minneapolis to Santiago

Sunday is one of the best days to book for cheap flights from Minneapolis to Santiago: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Minneapolis to Santiago

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Minneapolis to Santiago in 2025. You can also book with separate airlines for your outbound and return journeys, from $400 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Minneapolis to Santiago flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Minneapolis to Santiago airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Minneapolis to Santiago Flights

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*Available to One Key members.