$98 Cheap Flights from Myrtle Beach (MYR) to Chicago (MDW)

View $98 flight on Fri, Sep 19, 2025Opens in a new window

Popular airlines from Myrtle Beach Intl. Airport (MYR) to Chicago Midway Airport (MDW)

  • Plan, book, fly with confidence

  • trending down icon
    Be in the know
    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon
    Book smarter
    Save up to 30% on select hotels after you book a flight*
  • one key icon
    Earn twice
    Earn your airline miles on top of our OneKeyCash
    Learn about One Key

Cheap Flights from Myrtle Beach to Chicago (MYR-MDW)

Prices were available within the past 7 days and start at $98 for one-way flights and $195 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Southwest Airlines
Fri, Aug 29 - Mon, Sep 1
MYR
Myrtle Beach
MDW
Chicago
$195 Roundtrip, found 10 hours ago
$195
Roundtrip
found 10 hours ago
Select Southwest Airlines flight, departing Fri, Aug 29 from Myrtle Beach to Chicago, returning Mon, Sep 1, priced at $195 found 10 hours ago
Southwest Airlines
Sat, Jul 26 - Sat, Aug 2
MYR
Myrtle Beach
MDW
Chicago
$197 Roundtrip, found 1 day ago
$197
Roundtrip
found 1 day ago
Select Southwest Airlines flight, departing Sat, Jul 26 from Myrtle Beach to Chicago, returning Sat, Aug 2, priced at $197 found 1 day ago
Southwest Airlines
Tue, Jul 29 - Sat, Aug 2
MYR
Myrtle Beach
MDW
Chicago
$200 Roundtrip, found 4 days ago
$200
Roundtrip
found 4 days ago
Select Southwest Airlines flight, departing Tue, Jul 29 from Myrtle Beach to Chicago, returning Sat, Aug 2, priced at $200 found 4 days ago
Southwest Airlines
Sat, Aug 23 - Mon, Aug 25
MYR
Myrtle Beach
MDW
Chicago
$205 Roundtrip, found 1 day ago
$205
Roundtrip
found 1 day ago
Select Southwest Airlines flight, departing Sat, Aug 23 from Myrtle Beach to Chicago, returning Mon, Aug 25, priced at $205 found 1 day ago
Southwest Airlines
Thu, Aug 21 - Mon, Aug 25
MYR
Myrtle Beach
MDW
Chicago
$206 Roundtrip, found 1 day ago
$206
Roundtrip
found 1 day ago
Select Southwest Airlines flight, departing Thu, Aug 21 from Myrtle Beach to Chicago, returning Mon, Aug 25, priced at $206 found 1 day ago
Southwest Airlines
Wed, Aug 13 - Sun, Aug 17
MYR
Myrtle Beach
MDW
Chicago
$207 Roundtrip, found 11 hours ago
$207
Roundtrip
found 11 hours ago
Select Southwest Airlines flight, departing Wed, Aug 13 from Myrtle Beach to Chicago, returning Sun, Aug 17, priced at $207 found 11 hours ago
Southwest Airlines
Sat, Jul 26 - Sat, Aug 2
MYR
Myrtle Beach
MDW
Chicago
$208 Roundtrip, found 1 day ago
$208
Roundtrip
found 1 day ago
Select Southwest Airlines flight, departing Sat, Jul 26 from Myrtle Beach to Chicago, returning Sat, Aug 2, priced at $208 found 1 day ago
Southwest Airlines
Wed, Aug 13 - Sun, Aug 17
MYR
Myrtle Beach
MDW
Chicago
$212 Roundtrip, found 11 hours ago
$212
Roundtrip
found 11 hours ago
Select Southwest Airlines flight, departing Wed, Aug 13 from Myrtle Beach to Chicago, returning Sun, Aug 17, priced at $212 found 11 hours ago
Delta
Thu, Aug 21 - Mon, Aug 25
MYR
Myrtle Beach
MDW
Chicago
$215 Roundtrip, found 1 day ago
$215
Roundtrip
found 1 day ago
Select Delta flight, departing Thu, Aug 21 from Myrtle Beach to Chicago, returning Mon, Aug 25, priced at $215 found 1 day ago
Frontier Airlines
Sun, Jul 27 - Fri, Aug 15
MYR
Myrtle Beach
MDW
Chicago
$219 Roundtrip, found 9 hours ago
$219
Roundtrip
found 9 hours ago
Select Frontier Airlines flight, departing Sun, Jul 27 from Myrtle Beach to Chicago, returning Fri, Aug 15, priced at $219 found 9 hours ago

Find the cheapest month to fly from Myrtle Beach (MYR) to Chicago (MDW)

September is typically the cheapest month to fly

From $145 - $457 per traveler.

Graph displaying average flight prices per month

Flights from Myrtle Beach (MYR) to Chicago (MDW)
Origin airport
Myrtle Beach Intl.
Destination airport
Midway Intl.
Airlines serving
Delta, Frontier Airlines, Southwest Airlines
Roundtrip price
$195
Distance
737 mi
Average flight time
1 hour 10 mins

Myrtle Beach to Chicago Flights

The cheapest times to fly from Myrtle Beach to Chicago

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Myrtle Beach to Chicago are during the month of August. You can find some of the cheapest flights from Myrtle Beach to Chicago with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Myrtle Beach to Chicago

Sunday is one of the best days to book for cheap flights from Myrtle Beach to Chicago: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Myrtle Beach to Chicago

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Myrtle Beach to Chicago in 2025. You can also book with separate airlines for your outbound and return journeys, from $98 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Myrtle Beach to Chicago flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Myrtle Beach to Chicago airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Myrtle Beach Intl. Airport (MYR) to Midway Intl. Airport (MDW) cost?
You'll find cheap return fares from Myrtle Beach Intl. Airport (MYR) to Midway Intl. Airport (MDW) starting at $163. Grab a seat and be on your way. This information is based on the cheapest price found on Expedia for this return journey departing within the next three months. This airfare is for a Southwest Airlines and Spirit Airlines flight leaving MYR on July 23 2025 and touching down at MDW. The price was last updated on June 26 2025 and has not changed since.
What is the cheapest month to fly from MYR to MDW?
Secure a low fare by booking your nonstop flight from MYR to MDW in September. You can find a one-way Southwest Airlines flight for $98 leaving on September 30 2025. This price is based on the cheapest direct flight found on Expedia for this route in the next 330 days. The price was last updated on June 26 2025 and remains unchanged.
Which airlines fly direct from Myrtle Beach Intl. Airport (MYR) to Midway Intl. Airport (MDW)?
Take a nonstop flight with Southwest Airlines and journey straight from Myrtle Beach Intl. Airport (MYR) to Midway Intl. Airport (MDW).
What is the cheapest airline that flies from MYR to MDW?
Currently, the cheapest carrier offering one-way flights from MYR to MDW is Southwest Airlines. You can book a seat on this route from $98. This fare is based on the lowest price found on Expedia departing within the next three months. The flight takes off from MYR on September 20 2025. Prices were last updated on June 26 2025 and have not changed since.
How many flights per day from Myrtle Beach Intl. Airport (MYR) to Midway Intl. Airport (MDW)?
On average, Myrtle Beach Intl. Airport (MYR) has 6 direct flights to Midway Intl. Airport (MDW) per week. If you're looking for more options, use Expedia's filters to find flights with one or more stops. Fit in a quick visit to another city or just break up your journey.
What are the most popular departure times for flights from Myrtle Beach Intl. Airport (MYR) to Midway Intl. Airport (MDW)?
The 4 PM departures from MYR to MDW are the most sought after. These flights can come with a higher price due to their popularity. If you're looking to save, choose a less crowded time to fly.
What day of the week has the most flights from MYR to MDW?
If you depart on a Friday, you'll get the greatest range of choices for flights from Myrtle Beach Intl. Airport (MYR) to Midway Intl. Airport (MDW).
What is the earliest flight from Myrtle Beach Intl. Airport (MYR) to Midway Intl. Airport (MDW)?
Catch the earliest flight at around 3:35PM UTC-5, heading out of Myrtle Beach Intl. Airport (MYR). You'll be flying for roughly 2h 15m, landing at Midway Intl. Airport (MDW) at approximately 4:50PM UTC-6.
How long does it take to fly from Myrtle Beach Intl. Airport (MYR) to Midway Intl. Airport (MDW)?
It takes approximately 2 hours and 15 minutes to cover the 740 mi from MYR to MDW.
What is the best time to fly from Myrtle Beach Intl. Airport (MYR) to Midway Intl. Airport (MDW)?
To land at Midway Intl. Airport (MDW) on time, book a flight that leaves from Myrtle Beach Intl. Airport (MYR) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for Chicago from Myrtle Beach Intl. Airport (MYR)?
Midway Intl. Airport (MDW) is the only airport in Chicago with direct flights from Myrtle Beach Intl. Airport (MYR). Consider your options and find affordable fares on Expedia.
Is it cheaper to buy a plane ticket from Myrtle Beach Intl. Airport (MYR) to Midway Intl. Airport (MDW) last-minute?
Last-minute fares from MYR to MDW are generally more expensive. For the lowest rates, start searching for flights early. That said, if you're flexible with your travel dates, it's possible to land a cheap ticket right before your trip.
Is it cheaper to book a MYR to MDW flight and hotel package?
Opting for a MYR to MDW flight and hotel package is typically cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your trip in one place. Choose from our impressive range of hotels and then add flights, car rentals and activities to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Myrtle Beach Intl. Airport (MYR) to Midway Intl. Airport (MDW)?
It's generally possible to cancel or reschedule your MYR to MDW flight. However, if the booking was made more than 24 hours ago, additional charges may apply. Check your airline's policies in your itinerary to see what changes are possible and if any costs are involved. You'll also find further details on our Customer Service portal.

Explore a world of travel with Expedia

*Available to One Key members.