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$55 Cheap Flights from Myrtle Beach (MYR) to Syracuse (SYR)

View $55 flight on Thu, Nov 5, 2026Opens in a new window

Popular airlines from Myrtle Beach Intl. Airport (MYR) to Hancock Intl. Airport (SYR)

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Cheap Flights from Myrtle Beach to Syracuse (MYR-SYR)

Prices were available within the past 7 days and start at $55 for one-way flights and $111 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Allegiant Air
Thu, Nov 5 - Thu, Nov 12
MYR
Myrtle Beach
SYR
Syracuse
$111 Roundtrip, just found
$111
Roundtrip
just found
Select Allegiant Air flight, departing Thu, Nov 5 from Myrtle Beach to Syracuse, returning Thu, Nov 12, priced at $111 just found
Allegiant Air
Thu, Oct 22 - Sun, Oct 25
MYR
Myrtle Beach
SYR
Syracuse
$116 Roundtrip, found 1 hour ago
$116
Roundtrip
found 1 hour ago
Select Allegiant Air flight, departing Thu, Oct 22 from Myrtle Beach to Syracuse, returning Sun, Oct 25, priced at $116 found 1 hour ago
Allegiant Air
Thu, Nov 5 - Thu, Nov 12
MYR
Myrtle Beach
SYR
Syracuse
$117 Roundtrip, found 1 day ago
$117
Roundtrip
found 1 day ago
Select Allegiant Air flight, departing Thu, Nov 5 from Myrtle Beach to Syracuse, returning Thu, Nov 12, priced at $117 found 1 day ago
Allegiant Air
Thu, Oct 29 - Sun, Nov 1
MYR
Myrtle Beach
SYR
Syracuse
$122 Roundtrip, found 3 days ago
$122
Roundtrip
found 3 days ago
Select Allegiant Air flight, departing Thu, Oct 29 from Myrtle Beach to Syracuse, returning Sun, Nov 1, priced at $122 found 3 days ago
Allegiant Air
Thu, Nov 5 - Thu, Nov 12
MYR
Myrtle Beach
SYR
Syracuse
$130 Roundtrip, found 4 days ago
$130
Roundtrip
found 4 days ago
Select Allegiant Air flight, departing Thu, Nov 5 from Myrtle Beach to Syracuse, returning Thu, Nov 12, priced at $130 found 4 days ago
Allegiant Air
Thu, Oct 8 - Sun, Oct 11
MYR
Myrtle Beach
SYR
Syracuse
$134 Roundtrip, found 1 hour ago
$134
Roundtrip
found 1 hour ago
Select Allegiant Air flight, departing Thu, Oct 8 from Myrtle Beach to Syracuse, returning Sun, Oct 11, priced at $134 found 1 hour ago
Allegiant Air
Thu, Oct 22 - Thu, Oct 29
MYR
Myrtle Beach
SYR
Syracuse
$135 Roundtrip, found 3 hours ago
$135
Roundtrip
found 3 hours ago
Select Allegiant Air flight, departing Thu, Oct 22 from Myrtle Beach to Syracuse, returning Thu, Oct 29, priced at $135 found 3 hours ago
American Airlines
Thu, Sep 10 - Sat, Sep 12
MYR
Myrtle Beach
SYR
Syracuse
$261 Roundtrip, found 2 days ago
$261
Roundtrip
found 2 days ago
Select American Airlines flight, departing Thu, Sep 10 from Myrtle Beach to Syracuse, returning Sat, Sep 12, priced at $261 found 2 days ago
Delta
Thu, Sep 10 - Sat, Sep 12
MYR
Myrtle Beach
SYR
Syracuse
$310 Roundtrip, found 2 days ago
$310
Roundtrip
found 2 days ago
Select Delta flight, departing Thu, Sep 10 from Myrtle Beach to Syracuse, returning Sat, Sep 12, priced at $310 found 2 days ago
United
Wed, Sep 16 - Mon, Sep 21
MYR
Myrtle Beach
SYR
Syracuse
$349 Roundtrip, found 2 days ago
$349
Roundtrip
found 2 days ago
Select United flight, departing Wed, Sep 16 from Myrtle Beach to Syracuse, returning Mon, Sep 21, priced at $349 found 2 days ago

Alternative airports near Syracuse

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Hancock Intl. SYR. Cheapest and Closest option available. Average driving time to city center is 9 minutes. Flights from $438
SYR
Hancock Intl.
CheapestClosest
Average driving time to city center9 min
Flights from $438

What you need to know for your flight from Myrtle Beach Intl. to Hancock Intl.

North Myrtle Beach (MYR) to Syracuse (SYR) at a glance

Travel between North Myrtle Beach (MYR) and Syracuse (SYR) with a selection of airlines catering to this domestic short-haul route. Discover various options, from full-service airlines to budget-friendly choices, allowing you to find the perfect itinerary that aligns with your travel plans, budget, and schedule as you experience the sights and neighborhoods of Syracuse. Get ready to explore key flight details from Myrtle Beach International Airport (MYR) to Hancock International Airport (SYR).

  • Fastest flight duration: around 3 hours in-flight, plus roughly 1h 15m layover with one stop
  • Route distance: roughly 700 miles (1,130 km)
  • Flights per week: around 10 departures on average
  • Typical fares (one-way): economy tickets often range from $100–$425, depending on seasonality and how far ahead you book

Flights from Myrtle Beach International Airport (MYR) to Hancock International Airport (SYR)

According to recent traveler bookings, here are the top airlines favored for flights from North Myrtle Beach to Syracuse, typically featuring one-stop services. Popular layover options include Charlotte-Douglas International Airport (CLT) with about a 1h 15m layover, LaGuardia Airport (LGA) also around 1h 15m, and Ronald Reagan Washington National Airport (DCA) with a 1h 30m layover. This allows you to easily compare prices, total travel times, and cabin classes to find the best itinerary.

  • American Airlines: This major airline provides comprehensive service with one-stop flights, boasting one-way fares that typically fall between $100 and $410. It accounts for about 64% of departures on this route, featuring an in-flight duration of 3 hours and an overall travel time of approximately 4h 30m (including layover).
  • Delta: Another full-service airline, Delta offers one-stop options with one-way ticket prices generally ranging from $120 to $450. It represents around 32% of the flights on this route, with a flying time of 3 hours and a total journey duration of about 4h 30m (including a layover).
  • United: United Airlines also provides one-stop service, with one-way fares that typically range from $120 to $295. This airline covers roughly 4% of the departures for this route, with an in-flight time of 3 hours and a total travel duration of nearly 4h 30m (including layover).

Best time to fly from North Myrtle Beach (MYR) to Syracuse (SYR)

The most popular months for travelers flying from North Myrtle Beach to Syracuse are January, February, and April, when peak temperatures in Syracuse reach up to 45°F in April. If you prefer quieter travel, consider October, the least busy and relatively cheaper time to visit with fewer crowds and temperatures around 51.8°F. For better deals, August usually offers the lowest average one-way fare around $187. Flight availability peaks in February, with approximately 12 flights per week, making it easier to find convenient departure times. November has the fewest flights, with approximately 8 flights per week.

  • Cheapest time to fly: August usually offers good deals with average one-way fare around $187, roughly 19% cheaper than the yearly average.
  • More budget-friendly months to fly: May and July typically offer average one-way fares of around $190.
  • Most flight options: February has the highest number of flights from North Myrtle Beach to Syracuse, with approximately 12 flights per week, giving you more flexibility in scheduling your trip.
calendar iconMonthtemperature iconTemperaturecrowd level iconDemandflights iconWeekly Flightsprice iconAverage one-way Fare
January23.9°F (-4.5°C)High9$251
February25.3°F (-3.7°C)High12$236
March33.3°F (0.7°C)Average9$243
April45.0°F (7.2°C)High10$281
May57.4°F (14.1°C)Average9$189
June64.8°F (18.2°C)Average9$229
July70.5°F (21.4°C)Average11$190
August68.9°F (20.5°C)Average9$187
September62.4°F (16.9°C)Average9$214
October51.8°F (11.0°C)Low9$234
November39.6°F (4.2°C)Low8$243
December31.3°F (-0.4°C)Low9$274

*Average one-way fare is based on Expedia flight booking data from January 2025 to April 2026 for the specified route and travel class and may change depending on availability, dates, and demand.

Alternative routes from North Myrtle Beach (MYR) to Syracuse (SYR)

  • North Myrtle Beach to Syracuse (CRE-SYR): Located approximately 15 miles from Myrtle Beach International Airport (MYR), Grand Strand Airport (CRE) serves as a convenient departure point.
  • Myrtle Beach to Rome (MYR-RME): Griffiss International Airport (RME), situated about 36 miles from Hancock International Airport (SYR), offers a viable option for travelers heading to Rome.
  • North Myrtle Beach to Rome (CRE-RME): With Grand Strand Airport (CRE) just 15 miles from Myrtle Beach International Airport (MYR) and Griffiss International Airport (RME) around 36 miles from Hancock International Airport (SYR), this route provides ample travel choices.

How to find the best prices for flights from North Myrtle Beach (MYR) to Syracuse (SYR)

Getting some of the best deals on flights from North Myrtle Beach to Syracuse is all about timing and flexibility. Here are some key tips to help you save:

  1. Best times to book and fly: cheaper fares are usually available when booking 2-8 weeks in advance, which coincides with the typical booking window for most travelers. Evening (6 PM-12 AM) departures often have lower prices, while morning (5 AM-12 PM) flights are the most popular. Additionally, flying on Saturday generally offers cheaper rates, although Friday remains the busiest travel day.
  2. Set up price alerts: stay updated on price changes by using Expedia's Price Tracker. Receive alerts when fares drop for your selected route.
  3. Bundle and save: bundle your flight and hotel to save on Expedia, or unlock a hotel deal after booking your flight.*
  4. Compare flight options: use Expedia's search tool to compare airlines, routes, direct vs. non-direct flights, and flight times. You can also sort by price to find the most affordable options.
  5. Stay flexible with dates: being open to different travel days can sometimes help you find better prices on flights and hotels.
  6. Think about luggage: nowadays, it's important to check the airline's baggage policies to find the best value. That may be paying for an additional carry-on bag or booking a ticket with checked luggage included. Either way, double-check your allowance before confirming your booking to avoid excess baggage fees at the airport.

*Members only. Savings vary and are not available on all bundles. Select hotels.

Arriving at Hancock International Airport from Myrtle Beach International Airport

Syracuse welcomes travelers from North Myrtle Beach with a range of transport options based on price, convenience, and proximity. Syracuse city center is approximately a 10-minute drive (covering about 8 miles) from Hancock International Airport, depending on traffic. Here's how to reach Syracuse efficiently:

  • Hotel transfer: Transfers offer a convenient way to reach your hotel in Syracuse, with options including free hotel shuttles and private rides, which can be arranged in advance with your hotel.
  • Car rental: Renting a car from Hancock International Airport is a great option if you plan to explore and sightsee beyond the city. Browse cheap car rentals at Hancock International Airport on Expedia.
  • Taxi/ride-hailing: Taxis and ride-hailing services may be available from designated pickup areas outside the terminal, check locally on arrival.
  • Public transportation: From Hancock International Airport, travelers will find Syracuse Airport Bus Stop, a bus station, just about 0.1 miles away on foot, while the Syracuse Regional Transportation Center, a train station, is located approximately 5.8 miles away by car. Additionally, Syracuse Seaport, a seaport, is about 8.4 miles from the airport, also accessible by car.

Frequently asked questions

How much does a flight from Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Syracuse, NY (SYR-Hancock Intl.) cost?
You can find cheap one-way flights from $55 and cheap return flights from $111 Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Syracuse, NY (SYR-Hancock Intl.) with Expedia. One-way flights generally range between $235 and $703, and roundtrip flights usually range from $329 to $1001. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Syracuse, NY (SYR-Hancock Intl.) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Syracuse, NY (SYR-Hancock Intl.)?
The cheapest month to fly from MYR to SYR is November when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you're able to. Use the calendar view in your search to see which months have low fares on this route.
Which airlines fly direct from Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Syracuse, NY (SYR-Hancock Intl.)?
Enter MYR to SYR and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Syracuse, NY (SYR-Hancock Intl.)?
American Airlines is one of the cheapest airlines offering connecting flights from Myrtle Beach Intl. (MYR) to Hancock Intl. (SYR), with round-trip tickets starting from around $210 with a layover in Charlotte-Douglas Intl. (CLT). Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.*Prices based on flights available on Expedia in the last year.
How do I find cheap flights from Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Syracuse, NY (SYR-Hancock Intl.)?
To find a cheap flight from Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Syracuse, NY (SYR-Hancock Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Syracuse, NY (SYR-Hancock Intl.)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
What is the earliest flight from Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Syracuse, NY (SYR-Hancock Intl.)?
The earliest flight from Myrtle Beach International Airport (MYR) to Hancock International Airport (SYR) usually departs at around 5:00 AM, operated by American Airlines. This service is seasonal, active in November. An early flight can help you maximize your time in Syracuse. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Syracuse, NY (SYR-Hancock Intl.)?
The most popular departure times for flights from Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Syracuse, NY (SYR-Hancock Intl.) are in the early afternoon, from 12pm to 3pm. About 27% of passengers prefer this time window. Many major carriers, including American Airlines and Delta Airlines, offer flights during this window. This timing is great for those who want to enjoy a leisurely morning before heading to Syracuse.
How long does it take to fly from Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Syracuse, NY (SYR-Hancock Intl.)?
Flying from MYR to SYR with a connection usually takes about 4 hours 30 minutes, traveling roughly 669 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Syracuse, NY (SYR-Hancock Intl.)?
You can fly first class between MYR and SYR. First class cabins are available on:

  • American Airlines
  • Delta Air Lines
  • United Airlines

How do I earn miles on a Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Syracuse, NY (SYR-Hancock Intl.) flight with Expedia?
It's easy to earn miles on a Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Syracuse, NY (SYR-Hancock Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Syracuse from MYR (MYR)?
From MYR (MYR), you can fly into Hancock Intl. (SYR) to reach Syracuse. Some flights may connect through major hubs like Charlotte-Douglas Intl. (CLT), Liberty Intl. (EWR), Hartsfield-Jackson Atlanta Intl. (ATL) before reaching Syracuse. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Syracuse, NY (SYR-Hancock Intl.) at the last minute?
Typically, booking a last minute flight from Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Syracuse, NY (SYR-Hancock Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Syracuse, NY (SYR-Hancock Intl.) flight and hotel package?
Securing a Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Syracuse, NY (SYR-Hancock Intl.) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Syracuse, NY (SYR-Hancock Intl.)?
If you booked your Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Syracuse, NY (SYR-Hancock Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Myrtle Beach Intl.
Destination airport
Hancock Intl.
Airlines serving
Allegiant Air, American Airlines, Delta, United
Roundtrip price
$111
Distance
669 mi
Average flight time
1 hour 49 mins

Book with confidence

Myrtle Beach to Syracuse Flights

The cheapest times to fly from Myrtle Beach to Syracuse

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Myrtle Beach to Syracuse are during the month of November. You can find some of the cheapest flights from Myrtle Beach to Syracuse with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Myrtle Beach to Syracuse

Sunday is one of the best days to book for cheap flights from Myrtle Beach to Syracuse: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Myrtle Beach to Syracuse

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Myrtle Beach to Syracuse in 2026. You can also book with separate airlines for your outbound and return journeys, from $55 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Myrtle Beach to Syracuse flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Myrtle Beach to Syracuse airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Myrtle Beach to Syracuse Flights

*Flight schedules are subject to change.

*Available to One Key members.

 

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