$284 Cheap Flights from Panama City (PTY) to Manaus (MAO)

View $284 flight on Wed, Dec 17, 2025Opens in a new window

Popular airlines from Tocumen Intl. Airport (PTY) to Manaus (MAO-Eduardo Gomes Intl.)

  • notification illustration

    Be in the know

    Get alerts if flight prices drop or rise*
  • deals illustration

    Book smarter

    Save up to 30% on select hotels after you book a flight*
  • trophy illustration

    Earn twice

    Earn your airline miles on top of our OneKeyCash
    Learn about One Key

Cheap Flights from Panama City to Manaus (PTY-MAO)

Prices were available within the past 7 days and start at $284 for one-way flights and $539 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Copa
Mon, Feb 2 - Tue, Feb 17
PTY
Panama City
MAO
Manaus
$539 Roundtrip, found 5 days ago
$539
Roundtrip
found 5 days ago
Select Copa flight, departing Mon, Feb 2 from Panama City to Manaus, returning Tue, Feb 17, priced at $539 found 5 days ago
Copa
Tue, Feb 3 - Tue, Feb 17
PTY
Panama City
MAO
Manaus
$545 Roundtrip, found 4 hours ago
$545
Roundtrip
found 4 hours ago
Select Copa flight, departing Tue, Feb 3 from Panama City to Manaus, returning Tue, Feb 17, priced at $545 found 4 hours ago
avianca
Wed, May 13 - Wed, May 20
PTY
Panama City
MAO
Manaus
$571 Roundtrip, found 5 days ago
$571
Roundtrip
found 5 days ago
Select avianca flight, departing Wed, May 13 from Panama City to Manaus, returning Wed, May 20, priced at $571 found 5 days ago
avianca
Wed, Dec 31 - Thu, Jan 22
PTY
Panama City
MAO
Manaus
$573 Roundtrip, found 4 hours ago
$573
Roundtrip
found 4 hours ago
Select avianca flight, departing Wed, Dec 31 from Panama City to Manaus, returning Thu, Jan 22, priced at $573 found 4 hours ago
Copa
Thu, Feb 5 - Tue, Feb 17
PTY
Panama City
MAO
Manaus
$576 Roundtrip, found 5 days ago
$576
Roundtrip
found 5 days ago
Select Copa flight, departing Thu, Feb 5 from Panama City to Manaus, returning Tue, Feb 17, priced at $576 found 5 days ago
avianca
Wed, Dec 31 - Mon, Jan 19
PTY
Panama City
MAO
Manaus
$601 Roundtrip, found 4 hours ago
$601
Roundtrip
found 4 hours ago
Select avianca flight, departing Wed, Dec 31 from Panama City to Manaus, returning Mon, Jan 19, priced at $601 found 4 hours ago
Copa
Wed, Jan 14 - Mon, Jan 19
PTY
Panama City
MAO
Manaus
$607 Roundtrip, found 6 days ago
$607
Roundtrip
found 6 days ago
Select Copa flight, departing Wed, Jan 14 from Panama City to Manaus, returning Mon, Jan 19, priced at $607 found 6 days ago
Copa
Fri, Feb 6 - Sat, Feb 21
PTY
Panama City
MAO
Manaus
$611 Roundtrip, found 4 hours ago
$611
Roundtrip
found 4 hours ago
Select Copa flight, departing Fri, Feb 6 from Panama City to Manaus, returning Sat, Feb 21, priced at $611 found 4 hours ago
avianca
Wed, Feb 11 - Sat, Feb 21
PTY
Panama City
MAO
Manaus
$620 Roundtrip, found 2 days ago
$620
Roundtrip
found 2 days ago
Select avianca flight, departing Wed, Feb 11 from Panama City to Manaus, returning Sat, Feb 21, priced at $620 found 2 days ago
Copa
Tue, Jan 13 - Mon, Jan 19
PTY
Panama City
MAO
Manaus
$655 Roundtrip, found 6 days ago
$655
Roundtrip
found 6 days ago
Select Copa flight, departing Tue, Jan 13 from Panama City to Manaus, returning Mon, Jan 19, priced at $655 found 6 days ago

Alternative airports near Manaus

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Eduardo Gomes Intl. MAO. Cheapest and Closest option available. Average driving time to city center is 15 minutes. Flights from $767
MAO
Eduardo Gomes Intl.
CheapestClosest
Average driving time to city center15 min
Flights from $767
Flights from Panama City (PTY) to Manaus (MAO)
Origin airport
Tocumen Intl.
Destination airport
Eduardo Gomes Intl.
Airlines serving
Copa, avianca
Roundtrip price
$539
Distance
1572 mi
Average flight time
4 hours 3 mins

Panama City to Manaus Flights

The cheapest times to fly from Panama City to Manaus

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Panama City to Manaus are during the month of February. You can find some of the cheapest flights from Panama City to Manaus with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Panama City to Manaus

Sunday is one of the best days to book for cheap flights from Panama City to Manaus: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Panama City to Manaus

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Panama City to Manaus in 2026. You can also book with separate airlines for your outbound and return journeys, from $284 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Panama City to Manaus flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Panama City to Manaus airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Tocumen Intl. Airport (PTY) to Eduardo Gomes Intl. Airport (MAO) cost?
Secure a cheap one-way flight from $284 or cheap return flight from $539 from Tocumen Intl. Airport (PTY) to Eduardo Gomes Intl. Airport (MAO) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Tocumen Intl. Airport (PTY) to Eduardo Gomes Intl. Airport (MAO)?
February is the least expensive month to fly from PTY to MAO. Timing your trip outside of the busy season is often the key to landing a great deal.
Which airlines fly direct from Tocumen Intl. Airport (PTY) to Eduardo Gomes Intl. Airport (MAO)?
Take a nonstop flight with Copa Airlines and fly straight from Tocumen Intl. Airport (PTY) to Eduardo Gomes Intl. Airport (MAO).
What is the cheapest airline that flies from Tocumen Intl. Airport (PTY) to Eduardo Gomes Intl. Airport (MAO)?
To find the cheapest airline that'll fly you from PTY to MAO, use Expedia's filter tool. Tailor your search based on what's important to you, such as preferred carriers and seat class. You can then sort your results by "Price (lowest to highest)" to see the cheapest flights first.
How many flights per day from Tocumen Intl. Airport (PTY) to Eduardo Gomes Intl. Airport (MAO)?
On average you can take your pick of 5 direct flights per week from Tocumen Intl. Airport (PTY) to Eduardo Gomes Intl. Airport (MAO). For more flexibility, consider flights with layovers. Just enter your dates on Expedia and then filter your search to include one or two stops.
What are the most popular departure times for flights from Tocumen Intl. Airport (PTY) to Eduardo Gomes Intl. Airport (MAO)?
Flights between PTY and MAO are their busiest at 9 PM. If you're after a quieter experience and possibly cheaper tickets, choose a time when demand is lower.
What day of the week has the most flights from PTY to MAO?
If you travel on a Friday, you'll get the widest range of choices for flights from Tocumen Intl. Airport (PTY) to Eduardo Gomes Intl. Airport (MAO).
What is the earliest flight from Tocumen Intl. Airport (PTY) to Eduardo Gomes Intl. Airport (MAO)?
Take the earliest flight at around 9:31PM UTC-5, departing from Tocumen Intl. Airport (PTY). You'll be flying for around 3h 54m, arriving at Eduardo Gomes Intl. Airport (MAO) at approximately 2:25AM UTC-4.
How long does it take to fly from Tocumen Intl. Airport (PTY) to Eduardo Gomes Intl. Airport (MAO)?
Flights from PTY to MAO have an average travel time of 3 hours and 54 minutes. The distance between these two airports is 1,550 mi.
What airline has the least delays from PTY to MAO?
Consider traveling with Copa Airlines if you'd like to go straight from Tocumen Intl. Airport (PTY) to Eduardo Gomes Intl. Airport (MAO) without any interruptions. This airline has the best track record for punctuality, with an on-time score of 95%. Want to be updated if anything changes? You can keep an eye on your flight status using the Expedia App.
What is the best time to fly from Tocumen Intl. Airport (PTY) to Eduardo Gomes Intl. Airport (MAO)?
Select a flight from Tocumen Intl. Airport (PTY) to Eduardo Gomes Intl. Airport (MAO) that takes off before 3 PM to reduce the risk of cancellations and delays. Later departures are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for Manaus from Tocumen Intl. Airport (PTY)?
If you're flying on a direct flight from Tocumen Intl. Airport (PTY) to Manaus, Eduardo Gomes Intl. Airport (MAO) is the only airport you can land at.
Is it cheaper to buy a plane ticket from Tocumen Intl. Airport (PTY) to Eduardo Gomes Intl. Airport (MAO) last-minute?
Booking your ticket from PTY to MAO just before your trip is generally more expensive. However, if there's some wiggle room with your itinerary, you could score a cheap last-minute fare.
Is it cheaper to book a PTY to MAO flight and hotel package?
Securing a PTY to MAO flight and hotel package is generally cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your travels in one place. Select from our wide range of hotels and then add flights, car rentals and activities to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Tocumen Intl. Airport (PTY) to Eduardo Gomes Intl. Airport (MAO)?
If you booked your PTY to MAO flight in the last 24 hours, you may be able to modify or cancel it at no cost. Depending on the airline and the type of ticket you have, additional charges may apply for changes after that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal for more information.

Explore a world of travel with Expedia

*Available to One Key members.