$543 Cheap Flights from Rochester (ROC) to Santiago (SCL)

View $543 flight on Mon, Feb 16, 2026Opens in a new window

Popular airlines from Greater Rochester Intl. Airport (ROC) to Santiago Intl. Airport (SCL)

Cheap Flights from Rochester to Santiago (ROC-SCL)

Prices were available within the past 7 days and start at $543 for one-way flights and $764 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Tue, Nov 4 - Mon, Nov 10
ROC
Rochester
SCL
Santiago
$764 Roundtrip, found 21 hours ago
$764
Roundtrip
found 21 hours ago
Select Delta flight, departing Tue, Nov 4 from Rochester to Santiago, returning Mon, Nov 10, priced at $764 found 21 hours ago
United
Thu, Jan 8 - Mon, Jan 26
ROC
Rochester
SCL
Santiago
$769 Roundtrip, found 3 days ago
$769
Roundtrip
found 3 days ago
Select United flight, departing Thu, Jan 8 from Rochester to Santiago, returning Mon, Jan 26, priced at $769 found 3 days ago
Delta
Mon, Nov 3 - Mon, Nov 10
ROC
Rochester
SCL
Santiago
$771 Roundtrip, found 21 hours ago
$771
Roundtrip
found 21 hours ago
Select Delta flight, departing Mon, Nov 3 from Rochester to Santiago, returning Mon, Nov 10, priced at $771 found 21 hours ago
Delta
Sun, Jan 11 - Thu, Jan 22
ROC
Rochester
SCL
Santiago
$773 Roundtrip, found 5 days ago
$773
Roundtrip
found 5 days ago
Select Delta flight, departing Sun, Jan 11 from Rochester to Santiago, returning Thu, Jan 22, priced at $773 found 5 days ago
JetBlue Airways
Mon, Oct 27 - Thu, Nov 6
ROC
Rochester
SCL
Santiago
$774 Roundtrip, found 18 hours ago
$774
Roundtrip
found 18 hours ago
Select JetBlue Airways flight, departing Mon, Oct 27 from Rochester to Santiago, returning Thu, Nov 6, priced at $774 found 18 hours ago
Delta
Sun, Dec 7 - Tue, Dec 23
ROC
Rochester
SCL
Santiago
$775 Roundtrip, found 5 days ago
$775
Roundtrip
found 5 days ago
Select Delta flight, departing Sun, Dec 7 from Rochester to Santiago, returning Tue, Dec 23, priced at $775 found 5 days ago
Delta
Mon, Feb 16 - Mon, Feb 23
ROC
Rochester
SCL
Santiago
$777 Roundtrip, found 5 days ago
$777
Roundtrip
found 5 days ago
Select Delta flight, departing Mon, Feb 16 from Rochester to Santiago, returning Mon, Feb 23, priced at $777 found 5 days ago
LATAM Airlines Group
Mon, Oct 27 - Thu, Nov 6
ROC
Rochester
SCL
Santiago
$779 Roundtrip, found 18 hours ago
$779
Roundtrip
found 18 hours ago
Select LATAM Airlines Group flight, departing Mon, Oct 27 from Rochester to Santiago, returning Thu, Nov 6, priced at $779 found 18 hours ago
JetBlue Airways
Mon, Oct 27 - Thu, Nov 6
ROC
Rochester
SCL
Santiago
$781 Roundtrip, found 18 hours ago
$781
Roundtrip
found 18 hours ago
Select JetBlue Airways flight, departing Mon, Oct 27 from Rochester to Santiago, returning Thu, Nov 6, priced at $781 found 18 hours ago
American Airlines
Sat, Feb 7 - Mon, Feb 16
ROC
Rochester
SCL
Santiago
$809 Roundtrip, found 1 hour ago
$809
Roundtrip
found 1 hour ago
Select American Airlines flight, departing Sat, Feb 7 from Rochester to Santiago, returning Mon, Feb 16, priced at $809 found 1 hour ago

Alternative airports near Santiago

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Arturo Merino Benitez SCL. Cheapest and Closest option available. Average driving time to city center is 17 minutes. Flights from $791
SCL
Arturo Merino Benitez
CheapestClosest
Average driving time to city center17 min
Flights from $791

Frequently asked questions

How much does a flight from Greater Rochester Intl. Airport (ROC) to Arturo Merino Benitez Airport (SCL) cost?
Secure a cheap one-way flight from $543 or cheap return flight from $764 from Greater Rochester Intl. Airport (ROC) to Arturo Merino Benitez Airport (SCL) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Greater Rochester Intl. Airport (ROC) to Arturo Merino Benitez Airport (SCL)?
The cheapest month to fly from ROC to SCL is November, when there's less demand. Off-peak season is often when you'll find lower airfares between these airports.
What is the cheapest airline that flies from Greater Rochester Intl. Airport (ROC) to Arturo Merino Benitez Airport (SCL)?
To find the cheapest airline flying from ROC to SCL, use Expedia's filter tool. Customize your search based on your travel needs, such as preferred carriers and seat class. You can then sort your results by "Price (lowest to highest)" to see the cheapest flights first.
How many flights per day from Greater Rochester Intl. Airport (ROC) to Arturo Merino Benitez Airport (SCL)?
Direct flights from Greater Rochester Intl. Airport (ROC) to Arturo Merino Benitez Airport (SCL) aren't available daily, so you'll need to take a flight with a layover. Explore your options with Expedia's filter tool. Enter your travel dates and pick either "1 Stop" or "2+ Stops."
What day of the week has the most flights from ROC to SCL?
Friday is typically the busiest day for flights, while Tuesday tends to be the quietest.* Keep in mind that flight schedules can change based on a number of factors, including the carrier and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Greater Rochester Intl. Airport (ROC) to Arturo Merino Benitez Airport (SCL)?
To reach Arturo Merino Benitez Airport (SCL) on schedule, pick a flight that leaves Greater Rochester Intl. Airport (ROC) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Greater Rochester Intl. Airport (ROC) to Arturo Merino Benitez Airport (SCL) last-minute?
Booking your plane ticket from ROC to SCL just before your trip is generally more expensive. But if you're flexible with your itinerary, you could grab a cheap last-minute fare.
Is it cheaper to book a ROC to SCL flight and hotel package?
Compared with arranging flights and hotels separately, booking a ROC to SCL flight and hotel package with Expedia could result in significant savings. What's more, having everything in one convenient place takes the hassle out of travel planning. Simply secure your flights and choose from our extensive range of hotels, then tailor your trip with extras like tours and car rentals.
Can I cancel or change the date of my flight from Greater Rochester Intl. Airport (ROC) to Arturo Merino Benitez Airport (SCL)?
Typically, you can modify or cancel your ROC to SCL flight. However, additional charges may apply, especially if your booking was made over 24 hours ago. Check your itinerary for the airline's guidelines and fees on flight changes, or if you want more information, head to our Customer Service portal.

Travel information

Origin airport
Greater Rochester Intl.
Destination airport
Arturo Merino Benitez
Airlines serving
Air Canada, American Airlines, Copa, Delta, LATAM Airlines Group, United
Roundtrip price
$764
Distance
5304 mi

Book with confidence

Rochester to Santiago Flights

The cheapest times to fly from Rochester to Santiago

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Rochester to Santiago are during the month of November. You can find some of the cheapest flights from Rochester to Santiago with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Rochester to Santiago

Sunday is one of the best days to book for cheap flights from Rochester to Santiago: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Rochester to Santiago

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Rochester to Santiago in 2025. You can also book with separate airlines for your outbound and return journeys, from $543 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Rochester to Santiago flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Rochester to Santiago airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Rochester to Santiago Flights

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*Available to One Key members.